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Which antibiotic decreases activity of CYP450 enzymes? - ANSWER ✓
erythromycin
Which antibiotics can cause bleeding? - ANSWER ✓ Penicillins, cephalasporins,
and fluoroquinolones
What antibiotics are metabolized by the liver? - ANSWER ✓ macrolides (-
thromycin) and nitroimidazoles (metronidazole)
What antibiotics cause a disulfiram response? - ANSWER ✓ cephalosporins and
metronidazole
Which antibiotic decreases enterohepatic circulation? - ANSWER ✓ penicillins,
long-term tetracyclines, and macrolides
Which antibiotics are nephrotoxic? - ANSWER ✓ Vancomycin and
aminoglycosides
Which antibiotics are ototoxic? - ANSWER ✓ Aminoglycosides and Vancomycin
Which antibiotics and hepatotoxic and can cause jaundice? - ANSWER ✓
macrolides and sulfonamides
, What natural products can cause bleeding? - ANSWER ✓ garlic or large amounts
of ginger.
How much water should people taking antibiotics drink? - ANSWER ✓ 6-8
glasses a day
What is Echinacea? How does it work? Who should not use it? - ANSWER ✓ It is
a natural product used to treat infection. It works by stimulating the immune
system. People with type I diabetes, or autoimmune disorders or transplant patients
should not take it.
St. Johns Wort can cause - ANSWER ✓ photosensitivity
define selective toxicity - ANSWER ✓ selectively finding and destroying
pathogens without damaging the host
describe the 3 ways in which selective toxicity is achieved - ANSWER ✓
disruption of bacterial cell wall (human cells do not have cell walls), inhibition of
enzymes unique to bacteria, disruption of protein synthesis in microbes
(mammalian ribosomes are different from bacterial).
How do penicillins and cephalosporins work? - ANSWER ✓ By weakening the
cell wall and promoting lysis and death
How do sulfonamides work? - ANSWER ✓ inhibit folic acid synthesis
How do aminoglycosides work? - ANSWER ✓ Lethal inhibition of protein
synthesis. This is the only group that causes lethal inhibition of protein synthesis
bacteriocidal vs bacteriostatic - ANSWER ✓ cidal: kills bacteria
static: inhibits growth
entero refers to - ANSWER ✓ small intestine
Pencillins can be grouped with... - ANSWER ✓ Cephalosporins and Carbapenems
can be grouped with...