, TESTBANK for Clinical Hematology and
Fundamentals of Hemostasis 6th Edition Denise M.
Harmening
Notes
1- The file is chapter after chapter.
2- We have shown you few pages sample.
3- The file contains all Appendix and Excel sheet
if it exists.
4- We have all what you need, we make update
at every time. There are many new editions
waiting you.
5- If you think you purchased the wrong file You
can contact us at every time, we can replace it
with true one.
Our email:
, Chapter 1: Morphology and Maturation of Human Blood Cells: Hematopoiesis
1. What is meant by medullary hematopoiesis?
A) Hematopoiesis in the spleen
B) Hematopoiesis in marrow
C) Hematopoiesis in liver
D) Hematopoiesis in thymus
Correct Answer: B
L.O.: 1-13
Taxonomy: 1
2. What percentage of erythrocytes is functional in peripheral blood after release from the bone
marrow?
A) 70%
B) 50%
C) 80%
D) 100%
Correct Answer: D
L.O.: 1-1, 1-13
Taxonomy: 1
3. The hematopoietic system consists of all the following except:
A) Thymus
B) Bone marrow
C) Kidneys
D) Spleen
Correct Answer: C
L.O.: 1-13
Taxonomy: 1
4. What is the sequence of maturity for the erythrocyte?
A) Pronormoblast, basophilic normoblast, polychromatophilic normoblast, orthochromatic
normoblast, reticulocyte, erythrocyte
B) Basophilic normoblast, pronormoblast, orthochromatic normoblast, reticulocyte, erythrocyte,
polychromatophilic normoblast
C) Orthochromatic normoblast, pronormoblast, reticulocyte, erythrocyte, basophilic normoblast,
polychromatophilic normoblast
D) Polychromatophilic normoblast, orthochromatic normoblast, pronormoblast, erythrocyte,
reticulocyte, basophilic normoblast
Correct Answer: A
L.O.: 1-8
Taxonomy: 3
Page 1
, Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
5. By increasing hematopoiesis, the hematopoietic system can respond to stimuli such as:
A) Homeostasis
B) Hypoxia
C) Clotting
D) Hyperplasia
Correct Answer: B
L.O.: 1-13
Taxonomy: 3
6. In which immature erythroid cell are nucleoli most visible?
A) Basophilic normoblast
B) Orthochromatic normoblast
C) Pronormoblast
D) Polychromatic normoblast
Correct Answer: C
L.O.: 1-8
Taxonomy: 1
7. What is the average diameter of a normal erythrocyte?
A) 3–5 µm
B) 2–4 µm
C) 8–10 µm
D) 7–8 µm
Correct Answer: D
L.O.: 1-2
Taxonomy: 1
8. Which of the following does not characterize the maturation of the granulocytic series?
A) Decrease in nuclear volume
B) Appearance and disappearance of primary granules
C) Nuclear chromatin clumping
D) Cytoplasmic color change from pink to blue
Correct Answer: D
L.O.: 1-10
Taxonomy: 2
Page 2
, Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
9. The sequence of maturity of the neutrophil is:
A) Myeloblast, promyelocyte, myelocyte, metamyelocyte, band neutrophil, segmented
neutrophil
B) Myeloblast, promyelocyte, metamyelocyte, myelocyte, band neutrophil, segmented
neutrophil
C) Myeloblast, promyelocyte, band neutrophil, metamyelocyte, myelocyte, segmented
neutrophil
D) Myeloblast, myelocyte, promyelocyte, metamyelocyte, band neutrophil, segmented
neutrophil
Correct Answer: A
L.O.: 1-9
Taxonomy: 3
10. The stage in granulocyte maturation where the nucleus appears kidney-shaped is evident in
what cell?
A) Promyelocyte
B) Band neutrophil
C) Metamyelocyte
D) Myelocyte
Correct Answer: C
L.O.: 1-10
Taxonomy: 1
11. What percentage of band neutrophils is present in normal adult peripheral blood?
A) 1%–4%
B) 2%–6%
C) 10%–12%
D) 4%–8%
Correct Answer: B
L.O.: 1-1, 1-2
Taxonomy: 1
12. The first sign of neutrophilic differentiation and appearance of secondary granules is evident
in what cell type?
A) Promyelocyte
B) Myelocyte
C) Segmented neutrophil
D) Metamyelocyte
Correct Answer: B
L.O.: 1-10
Page 3
, Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
Taxonomy: 2
13. Which cell in the granulocytic series is present in the greatest percentages in normal bone
marrow?
A) Band neutrophil
B) Promyelocyte
C) Metamyelocyte
D) Myelocyte
Correct Answer: A
L.O.: 1-9
Taxonomy: 1
14. Which characteristic is used to differentiate a large lymphocyte from a monocyte?
A) Distinct bluish-red granules
B) Blue-gray cytoplasm
C) Round nucleus
D) Indented cytoplasm from surrounding RBCs
Correct Answer: D
L.O.: 1-7
Taxonomy: 2
15. What color do the eosinophilic granules retain with the Wright's stain?
A) Bluish-purple
B) Reddish-orange
C) Clear
D) Purple-black
Correct Answer: B
L.O.: 1-2, 1-4
Taxonomy: 1
16. What stages do both basophils and eosinophils pass through in their sequence of maturity?
A) Promyelocyte, myelocyte, band cell, segmented cell
B) Myeloblast, promyelocyte, myelocyte, band cell, segmented cell
C) Myelocyte, metamyelocyte, band cell, segmented cell
D) Band cell, myelocyte, metamyelocyte, segmented cell
Correct Answer: C
L.O.: 1-9
Taxonomy: 2
Page 4
, Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
17. Which characteristic does not correspond with monocyte identification?
A) Scanty light blue cytoplasm
B) Digestive vacuoles
C) Lacy, delicate chromatin and indented nucleus
D) “Ground-glass” appearance of cytoplasm with evenly distributed fine granules
Correct Answer: A
L.O.: 1-6
Taxonomy: 2
18. What cell does the monocyte become upon entering the tissues?
A) Lymphocyte
B) Mast cell
C) Macrophage
D) Neutrophil
Correct Answer: C
L.O.: 1-6
Taxonomy: 1
19. The lymphoblast can be identified morphologically by what characteristics?
A) Small round nucleus, basophilic cytoplasm, nucleoli
B) Large round nucleus, basophilic cytoplasm, no nucleoli
C) Small eccentric nucleus, basophilic cytoplasm, nucleoli
D) Large round nucleus, basophilic cytoplasm, nucleoli
Correct Answer: D
L.O.: 1-5
Taxonomy: 2
20. What percentage of lymphocytes is present in normal adult peripheral blood?
A) 50%–70%
B) 20%–44%
C) 10%–30%
D) 5%–10%
Correct Answer: B
L.O.: 1-1, 1-2
Taxonomy: 1
Page 5
, Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
21. Where does T-cell differentiation take place?
A) Thymus
B) Bone marrow
C) Liver
D) Spleen
Correct Answer: A
L.O.: 1-5, 1-13
Taxonomy: 1
22. A cell that is described as having a horseshoe nucleus with condensed chromatin and pink
cytoplasm due to the presence of secondary granules is called:
A) Eosinophil
B) Band Neutrophil
C) Segmented Neutrophil
D) Basophil
Correct Answer: B
L.O.: 1-3
Taxonomy: 2
23. Ultimately, megakaryocytes lead to the formation of non-nucleated, cytoplasmic fragments
called:
A) Granulocytes
B) Thrombocytes
C) Lymphocytes
D) Monocytes
Correct Answer: B
L.O.: 1-13
Taxonomy: 1
24. What is the primary purpose of cytokines?
A) Oxygen supply to tissues
B) Phagocytosis in infections
C) Assisting in the growth of bone marrow cells
D) Cell-mediated immunity
Correct Answer: C
L.O.: 1-14
Taxonomy: 2
Page 6
, Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
25. Plasmacytes represent the end stage of what cell lineage?
A) B lymphocytes
B) T lymphocytes
C) Prolymphocytes
D) Lymphoblasts
Correct Answer: A
L.O.: 1-12
Taxonomy: 1
26. Which of the following is the largest hematopoietic cell in the bone marrow?
A) Pronormoblast
B) Myeloblast
C) Megakaryocyte
D) Plasma cell
Correct Answer: C
L.O.: 1-13
Taxonomy: 1
27. A segmented neutrophil is differentiated by:
A) Definite continuing lobe for the nucleus
B) Heavily clumped chromatin
C) Light pink cytoplasm
D) Nucleus lobes folded back over on itself
Correct Answer: D
L.O.: 1-3
Taxonomy: 2
Page 7
, Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
28. A cell that is observed to be large in size, round nucleus with prominent nucleoli, and very
slight basophilic cytoplasm with no or few granules is identified as:
A) Myelocyte
B) Metamyelocyte
C) Promyelocyte
D) Myeloblast
Correct Answer: D
L.O.: 1-11
Taxonomy: 3
29. Purple-black granules that are water soluble and unevenly distributed throughout a cell are
found in:
A) Basophils
B) Eosinophils
C) Neutrophils
D) Megakaryocytes
Correct Answer: A
L.O.: 1-4
Taxonomy: 1
30. Which cell can produce immunoglobulins?
A) T lymphocyte
B) Segmented Neutrophil
C) Megakaryocyte
D) Plasmacyte
Correct Answer: D
L.O.: 1-12
Taxonomy: 1
31. The first recognizable cell in granulopoiesis is:
A) Promyelocyte
B) Myeloblast
C) Lymphoblast
D) Promonocyte
Correct Answer: B
L.O.: 1-11
Taxonomy: 2
Page 8
Fundamentals of Hemostasis 6th Edition Denise M.
Harmening
Notes
1- The file is chapter after chapter.
2- We have shown you few pages sample.
3- The file contains all Appendix and Excel sheet
if it exists.
4- We have all what you need, we make update
at every time. There are many new editions
waiting you.
5- If you think you purchased the wrong file You
can contact us at every time, we can replace it
with true one.
Our email:
, Chapter 1: Morphology and Maturation of Human Blood Cells: Hematopoiesis
1. What is meant by medullary hematopoiesis?
A) Hematopoiesis in the spleen
B) Hematopoiesis in marrow
C) Hematopoiesis in liver
D) Hematopoiesis in thymus
Correct Answer: B
L.O.: 1-13
Taxonomy: 1
2. What percentage of erythrocytes is functional in peripheral blood after release from the bone
marrow?
A) 70%
B) 50%
C) 80%
D) 100%
Correct Answer: D
L.O.: 1-1, 1-13
Taxonomy: 1
3. The hematopoietic system consists of all the following except:
A) Thymus
B) Bone marrow
C) Kidneys
D) Spleen
Correct Answer: C
L.O.: 1-13
Taxonomy: 1
4. What is the sequence of maturity for the erythrocyte?
A) Pronormoblast, basophilic normoblast, polychromatophilic normoblast, orthochromatic
normoblast, reticulocyte, erythrocyte
B) Basophilic normoblast, pronormoblast, orthochromatic normoblast, reticulocyte, erythrocyte,
polychromatophilic normoblast
C) Orthochromatic normoblast, pronormoblast, reticulocyte, erythrocyte, basophilic normoblast,
polychromatophilic normoblast
D) Polychromatophilic normoblast, orthochromatic normoblast, pronormoblast, erythrocyte,
reticulocyte, basophilic normoblast
Correct Answer: A
L.O.: 1-8
Taxonomy: 3
Page 1
, Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
5. By increasing hematopoiesis, the hematopoietic system can respond to stimuli such as:
A) Homeostasis
B) Hypoxia
C) Clotting
D) Hyperplasia
Correct Answer: B
L.O.: 1-13
Taxonomy: 3
6. In which immature erythroid cell are nucleoli most visible?
A) Basophilic normoblast
B) Orthochromatic normoblast
C) Pronormoblast
D) Polychromatic normoblast
Correct Answer: C
L.O.: 1-8
Taxonomy: 1
7. What is the average diameter of a normal erythrocyte?
A) 3–5 µm
B) 2–4 µm
C) 8–10 µm
D) 7–8 µm
Correct Answer: D
L.O.: 1-2
Taxonomy: 1
8. Which of the following does not characterize the maturation of the granulocytic series?
A) Decrease in nuclear volume
B) Appearance and disappearance of primary granules
C) Nuclear chromatin clumping
D) Cytoplasmic color change from pink to blue
Correct Answer: D
L.O.: 1-10
Taxonomy: 2
Page 2
, Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
9. The sequence of maturity of the neutrophil is:
A) Myeloblast, promyelocyte, myelocyte, metamyelocyte, band neutrophil, segmented
neutrophil
B) Myeloblast, promyelocyte, metamyelocyte, myelocyte, band neutrophil, segmented
neutrophil
C) Myeloblast, promyelocyte, band neutrophil, metamyelocyte, myelocyte, segmented
neutrophil
D) Myeloblast, myelocyte, promyelocyte, metamyelocyte, band neutrophil, segmented
neutrophil
Correct Answer: A
L.O.: 1-9
Taxonomy: 3
10. The stage in granulocyte maturation where the nucleus appears kidney-shaped is evident in
what cell?
A) Promyelocyte
B) Band neutrophil
C) Metamyelocyte
D) Myelocyte
Correct Answer: C
L.O.: 1-10
Taxonomy: 1
11. What percentage of band neutrophils is present in normal adult peripheral blood?
A) 1%–4%
B) 2%–6%
C) 10%–12%
D) 4%–8%
Correct Answer: B
L.O.: 1-1, 1-2
Taxonomy: 1
12. The first sign of neutrophilic differentiation and appearance of secondary granules is evident
in what cell type?
A) Promyelocyte
B) Myelocyte
C) Segmented neutrophil
D) Metamyelocyte
Correct Answer: B
L.O.: 1-10
Page 3
, Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
Taxonomy: 2
13. Which cell in the granulocytic series is present in the greatest percentages in normal bone
marrow?
A) Band neutrophil
B) Promyelocyte
C) Metamyelocyte
D) Myelocyte
Correct Answer: A
L.O.: 1-9
Taxonomy: 1
14. Which characteristic is used to differentiate a large lymphocyte from a monocyte?
A) Distinct bluish-red granules
B) Blue-gray cytoplasm
C) Round nucleus
D) Indented cytoplasm from surrounding RBCs
Correct Answer: D
L.O.: 1-7
Taxonomy: 2
15. What color do the eosinophilic granules retain with the Wright's stain?
A) Bluish-purple
B) Reddish-orange
C) Clear
D) Purple-black
Correct Answer: B
L.O.: 1-2, 1-4
Taxonomy: 1
16. What stages do both basophils and eosinophils pass through in their sequence of maturity?
A) Promyelocyte, myelocyte, band cell, segmented cell
B) Myeloblast, promyelocyte, myelocyte, band cell, segmented cell
C) Myelocyte, metamyelocyte, band cell, segmented cell
D) Band cell, myelocyte, metamyelocyte, segmented cell
Correct Answer: C
L.O.: 1-9
Taxonomy: 2
Page 4
, Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
17. Which characteristic does not correspond with monocyte identification?
A) Scanty light blue cytoplasm
B) Digestive vacuoles
C) Lacy, delicate chromatin and indented nucleus
D) “Ground-glass” appearance of cytoplasm with evenly distributed fine granules
Correct Answer: A
L.O.: 1-6
Taxonomy: 2
18. What cell does the monocyte become upon entering the tissues?
A) Lymphocyte
B) Mast cell
C) Macrophage
D) Neutrophil
Correct Answer: C
L.O.: 1-6
Taxonomy: 1
19. The lymphoblast can be identified morphologically by what characteristics?
A) Small round nucleus, basophilic cytoplasm, nucleoli
B) Large round nucleus, basophilic cytoplasm, no nucleoli
C) Small eccentric nucleus, basophilic cytoplasm, nucleoli
D) Large round nucleus, basophilic cytoplasm, nucleoli
Correct Answer: D
L.O.: 1-5
Taxonomy: 2
20. What percentage of lymphocytes is present in normal adult peripheral blood?
A) 50%–70%
B) 20%–44%
C) 10%–30%
D) 5%–10%
Correct Answer: B
L.O.: 1-1, 1-2
Taxonomy: 1
Page 5
, Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
21. Where does T-cell differentiation take place?
A) Thymus
B) Bone marrow
C) Liver
D) Spleen
Correct Answer: A
L.O.: 1-5, 1-13
Taxonomy: 1
22. A cell that is described as having a horseshoe nucleus with condensed chromatin and pink
cytoplasm due to the presence of secondary granules is called:
A) Eosinophil
B) Band Neutrophil
C) Segmented Neutrophil
D) Basophil
Correct Answer: B
L.O.: 1-3
Taxonomy: 2
23. Ultimately, megakaryocytes lead to the formation of non-nucleated, cytoplasmic fragments
called:
A) Granulocytes
B) Thrombocytes
C) Lymphocytes
D) Monocytes
Correct Answer: B
L.O.: 1-13
Taxonomy: 1
24. What is the primary purpose of cytokines?
A) Oxygen supply to tissues
B) Phagocytosis in infections
C) Assisting in the growth of bone marrow cells
D) Cell-mediated immunity
Correct Answer: C
L.O.: 1-14
Taxonomy: 2
Page 6
, Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
25. Plasmacytes represent the end stage of what cell lineage?
A) B lymphocytes
B) T lymphocytes
C) Prolymphocytes
D) Lymphoblasts
Correct Answer: A
L.O.: 1-12
Taxonomy: 1
26. Which of the following is the largest hematopoietic cell in the bone marrow?
A) Pronormoblast
B) Myeloblast
C) Megakaryocyte
D) Plasma cell
Correct Answer: C
L.O.: 1-13
Taxonomy: 1
27. A segmented neutrophil is differentiated by:
A) Definite continuing lobe for the nucleus
B) Heavily clumped chromatin
C) Light pink cytoplasm
D) Nucleus lobes folded back over on itself
Correct Answer: D
L.O.: 1-3
Taxonomy: 2
Page 7
, Chapter 1: Morphology of Human Blood Cells: Hematopoiesis
28. A cell that is observed to be large in size, round nucleus with prominent nucleoli, and very
slight basophilic cytoplasm with no or few granules is identified as:
A) Myelocyte
B) Metamyelocyte
C) Promyelocyte
D) Myeloblast
Correct Answer: D
L.O.: 1-11
Taxonomy: 3
29. Purple-black granules that are water soluble and unevenly distributed throughout a cell are
found in:
A) Basophils
B) Eosinophils
C) Neutrophils
D) Megakaryocytes
Correct Answer: A
L.O.: 1-4
Taxonomy: 1
30. Which cell can produce immunoglobulins?
A) T lymphocyte
B) Segmented Neutrophil
C) Megakaryocyte
D) Plasmacyte
Correct Answer: D
L.O.: 1-12
Taxonomy: 1
31. The first recognizable cell in granulopoiesis is:
A) Promyelocyte
B) Myeloblast
C) Lymphoblast
D) Promonocyte
Correct Answer: B
L.O.: 1-11
Taxonomy: 2
Page 8
