PHARMACOLOGY MODULE #1,#2 & #3
EXAM REVIEW, PHARMACOLOGY
MODULE 3, ADV PHARM 5334 UTA
EXAM 1 EXAM WITH CORRECT
QUESTIONS AND ANSWERS 2025
1. What are the four phases of pharmacokinetics? - CORRECT-ANSWERS- Absorption,
distribution, metabolism, excretion
2. Bioavailability - CORRECT-ANSWERSThe extent of drug that becomes available to the
body after absorption
3. "Free Drug" - CORRECT-ANSWERS- The drug that is not bound to protein that is free to
exert a therapeutic effect
4. Nicotine is a? What (3) effects does it have? - CORRECT-ANSWERS- A CYP 450 inducer
- Increase metabolism of drug and result in decreased effects and shortened half-
life
5. Grapefruit Juice is a? What (3) effects does it have? - CORRECT-ANSWERS- A CYP 450
Inhibitor
- Decreased metabolism
- Drug toxicity
, - Shorted half life
6. Kidneys - CORRECT-ANSWERSThe main organs responsible for drug excretion
7. Half-life - CORRECT-ANSWERSThe time required for one half of the drug to be removed
from the body
8. Peak Effect - CORRECT-ANSWERSThe time taken for the drug to reach maximum
therapeutic response
9. Peak Level - CORRECT-ANSWERS- The highest concentration of drug in blood
10. Drug Polymorphism - CORRECT-ANSWERSThe effect of a patient's age, gender, size,
body composition and other characteristics on the pharmacokinetics of a specific drug
11. Drug Polymorphism can be categorized into what (3) different factors. - CORRECT-
ANSWERS1. Environmental (diet & nutritional status)
12. 2. Cultural
13. 3. Genetic factors
14. How can high-fat diets affect absorption? How can malnutrition affect absorption? -
CORRECT-ANSWERS- High Fat Diets = increased absorption of many drugs
- Malnutrition = alter the ability to absorb or eliminate medication
,15. Drugs like Heroin and LSD are considered category ____? - CORRECT-ANSWERS-
Category I
16. The normal range for albumin is _____ - _____ grams/dL - CORRECT-ANSWERS- 4-6
grams/dl
17. If the gastric pH level is high, this means the stomach is more _______ than normal. -
CORRECT-ANSWERS- Alkaline
18. Prodrug - CORRECT-ANSWERS- A drug that is converted from an inactive form into an
active metabolite through biotransformation in the liver
19. Paradoxical Reaction - CORRECT-ANSWERS- The opposite reaction than what is expected
with the specific drug
20. The three names for Medications? - CORRECT-ANSWERS- Chemical, trade and generic
21. Chemical name of a drug refers to? - CORRECT-ANSWERS- The chemical structure
22. Trade name / brand name of a medication - CORRECT-ANSWERS- proprietary name
- more expensive than generic
- Shorter, easier name
23. Generic Medication - CORRECT-ANSWERS- Most commonly used
- most prescriptions are
24. Pharmacokinetics of Oral Medications (4 steps) - CORRECT-ANSWERS1. Drug is ingested
, 25. 2. Disintegrated
26. 3. Forms a dissolution
27. 4. Absorption can occur
28. What is absorption? - CORRECT-ANSWERS- The movement of a drug from its site of
administration into the bloodstream for distributions to tissues
29. A drug that is absorbed through the intestines must ______ pass through the _______
before it reaches the ________ circulation. - CORRECT-ANSWERS- A drug that is
absorbed through the intestines must first pass through the liver before it reaches the
systemic circulation
30. High first-pass effect - CORRECT-ANSWERS- A large portion is changed into an inactive
metabolite
31. Which routes of medication administration would be impacted by first pass effect? -
CORRECT-ANSWERS- Anything GI related can have first pass effect
- Oral and Rectal administration
32. Which routes will not be impacted by first-pass effect? - CORRECT-ANSWERS- Parenteral
and topical
33. What are the (3) basic routes of medication administration? - CORRECT-ANSWERS-
Enteral, Parenteral, and topical
EXAM REVIEW, PHARMACOLOGY
MODULE 3, ADV PHARM 5334 UTA
EXAM 1 EXAM WITH CORRECT
QUESTIONS AND ANSWERS 2025
1. What are the four phases of pharmacokinetics? - CORRECT-ANSWERS- Absorption,
distribution, metabolism, excretion
2. Bioavailability - CORRECT-ANSWERSThe extent of drug that becomes available to the
body after absorption
3. "Free Drug" - CORRECT-ANSWERS- The drug that is not bound to protein that is free to
exert a therapeutic effect
4. Nicotine is a? What (3) effects does it have? - CORRECT-ANSWERS- A CYP 450 inducer
- Increase metabolism of drug and result in decreased effects and shortened half-
life
5. Grapefruit Juice is a? What (3) effects does it have? - CORRECT-ANSWERS- A CYP 450
Inhibitor
- Decreased metabolism
- Drug toxicity
, - Shorted half life
6. Kidneys - CORRECT-ANSWERSThe main organs responsible for drug excretion
7. Half-life - CORRECT-ANSWERSThe time required for one half of the drug to be removed
from the body
8. Peak Effect - CORRECT-ANSWERSThe time taken for the drug to reach maximum
therapeutic response
9. Peak Level - CORRECT-ANSWERS- The highest concentration of drug in blood
10. Drug Polymorphism - CORRECT-ANSWERSThe effect of a patient's age, gender, size,
body composition and other characteristics on the pharmacokinetics of a specific drug
11. Drug Polymorphism can be categorized into what (3) different factors. - CORRECT-
ANSWERS1. Environmental (diet & nutritional status)
12. 2. Cultural
13. 3. Genetic factors
14. How can high-fat diets affect absorption? How can malnutrition affect absorption? -
CORRECT-ANSWERS- High Fat Diets = increased absorption of many drugs
- Malnutrition = alter the ability to absorb or eliminate medication
,15. Drugs like Heroin and LSD are considered category ____? - CORRECT-ANSWERS-
Category I
16. The normal range for albumin is _____ - _____ grams/dL - CORRECT-ANSWERS- 4-6
grams/dl
17. If the gastric pH level is high, this means the stomach is more _______ than normal. -
CORRECT-ANSWERS- Alkaline
18. Prodrug - CORRECT-ANSWERS- A drug that is converted from an inactive form into an
active metabolite through biotransformation in the liver
19. Paradoxical Reaction - CORRECT-ANSWERS- The opposite reaction than what is expected
with the specific drug
20. The three names for Medications? - CORRECT-ANSWERS- Chemical, trade and generic
21. Chemical name of a drug refers to? - CORRECT-ANSWERS- The chemical structure
22. Trade name / brand name of a medication - CORRECT-ANSWERS- proprietary name
- more expensive than generic
- Shorter, easier name
23. Generic Medication - CORRECT-ANSWERS- Most commonly used
- most prescriptions are
24. Pharmacokinetics of Oral Medications (4 steps) - CORRECT-ANSWERS1. Drug is ingested
, 25. 2. Disintegrated
26. 3. Forms a dissolution
27. 4. Absorption can occur
28. What is absorption? - CORRECT-ANSWERS- The movement of a drug from its site of
administration into the bloodstream for distributions to tissues
29. A drug that is absorbed through the intestines must ______ pass through the _______
before it reaches the ________ circulation. - CORRECT-ANSWERS- A drug that is
absorbed through the intestines must first pass through the liver before it reaches the
systemic circulation
30. High first-pass effect - CORRECT-ANSWERS- A large portion is changed into an inactive
metabolite
31. Which routes of medication administration would be impacted by first pass effect? -
CORRECT-ANSWERS- Anything GI related can have first pass effect
- Oral and Rectal administration
32. Which routes will not be impacted by first-pass effect? - CORRECT-ANSWERS- Parenteral
and topical
33. What are the (3) basic routes of medication administration? - CORRECT-ANSWERS-
Enteral, Parenteral, and topical
