8/21/25, 8:53
AM
N300 PHARM FINAL EXAM QUESTIONS AND
ANSWERS WITH COMPLETE SOLUTIONS
VERIFIED UPDATE 2025/2026
Terms in this set (73)
DMARDS purpose restrict immune system response: treatment of
RA, prevents organ rejection, slows worstening
of dx, manage IBD
DMARDS NI liver enzyems + CBC, risk for infection, screen for TB
+ Hep B, no live vax, 3 month to work, no preggo
Methotrexate SE + NI GI ulcerations, take w food, no vitamins (decreases TE)
Sulfasalazine SE + NI GI
Hydroxychloroquine SE + Retinal damage, blindness, baseline eye exam + every 6
NI months
Etanercept SE + NI SubQ irritation, SJS, HF, ensure solution is clear
Cyclosporine SE + NI nephro tox, extra hair growth, gingival hyperplasia, take
w milk or juice
Prednisone MOA inhibits prostoglandin synthesis
Prednisone TE Take while waiting for DMARDs to work, RA flare up
Prednisone SE 8 S's
Colchicine MOA inhibits Cox1 + Cox2
Colchicine TE aborts acute gout attacks
Colchicine SE BIG P + Rhabdo
Colchicine Contra kidney dx, other anti coag, HTN meds
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AM
Allopurinol MOA inhibits production of uric acid
Allopurinol TE used for chronic gout >3-4 episodes/year
Allopurinol SE Hypersensitivity, kidney damage, dont start med until
acute episode resolves
Allopurinol Contra warfrin, caution kidney + liver dx
Duloxetine MOA SNRI
Duloxetine TE fibromalgia + nerve pain
Duloxetine SE SNRI S/E
Pregabalin MOA increase GABA, cannot get high from it
Pregabalin TE nerve pain + fibromyalgia
Pregabalin SE sedatio, dizziness, blurred vision, angioedema, rhabdo
Pregabalin Contra other CNS depressants, ACE+ ARB (higher risk for
angioedema)
Calcium citrate use + TE maintain MS function, increase Ca levels, less
osteoporosis
Calcium citrate SE hypercalcemia
Calcium citrate contra Iv calcium, IV dijoxin
Calcium citrate NI chew tablet, Iv room temp, EKG, H2O
Raloxifene use + TE decrease bone reabsorbtion, protects breast + endo
cancer
Raloxifene SE blood clots, hot flashes, hep, not for males
Raloxifene NI + contra liver dx, hx of blood clots, males, stop 3 days prior to
surgery
Alendronate + calcium inhibits bone reabsorbition, osteoporosis
salmon use + TE
alendronate SE esophagitis, GI upset, osteonecrosis of the jaw
alendronate contra + NI no oranges + caffiene, take in AM, for men, see dentist
Calcitonin- salmon SE naseau, nasal spray
2/
5
AM
N300 PHARM FINAL EXAM QUESTIONS AND
ANSWERS WITH COMPLETE SOLUTIONS
VERIFIED UPDATE 2025/2026
Terms in this set (73)
DMARDS purpose restrict immune system response: treatment of
RA, prevents organ rejection, slows worstening
of dx, manage IBD
DMARDS NI liver enzyems + CBC, risk for infection, screen for TB
+ Hep B, no live vax, 3 month to work, no preggo
Methotrexate SE + NI GI ulcerations, take w food, no vitamins (decreases TE)
Sulfasalazine SE + NI GI
Hydroxychloroquine SE + Retinal damage, blindness, baseline eye exam + every 6
NI months
Etanercept SE + NI SubQ irritation, SJS, HF, ensure solution is clear
Cyclosporine SE + NI nephro tox, extra hair growth, gingival hyperplasia, take
w milk or juice
Prednisone MOA inhibits prostoglandin synthesis
Prednisone TE Take while waiting for DMARDs to work, RA flare up
Prednisone SE 8 S's
Colchicine MOA inhibits Cox1 + Cox2
Colchicine TE aborts acute gout attacks
Colchicine SE BIG P + Rhabdo
Colchicine Contra kidney dx, other anti coag, HTN meds
1/
5
, 8/21/25, 8:53
AM
Allopurinol MOA inhibits production of uric acid
Allopurinol TE used for chronic gout >3-4 episodes/year
Allopurinol SE Hypersensitivity, kidney damage, dont start med until
acute episode resolves
Allopurinol Contra warfrin, caution kidney + liver dx
Duloxetine MOA SNRI
Duloxetine TE fibromalgia + nerve pain
Duloxetine SE SNRI S/E
Pregabalin MOA increase GABA, cannot get high from it
Pregabalin TE nerve pain + fibromyalgia
Pregabalin SE sedatio, dizziness, blurred vision, angioedema, rhabdo
Pregabalin Contra other CNS depressants, ACE+ ARB (higher risk for
angioedema)
Calcium citrate use + TE maintain MS function, increase Ca levels, less
osteoporosis
Calcium citrate SE hypercalcemia
Calcium citrate contra Iv calcium, IV dijoxin
Calcium citrate NI chew tablet, Iv room temp, EKG, H2O
Raloxifene use + TE decrease bone reabsorbtion, protects breast + endo
cancer
Raloxifene SE blood clots, hot flashes, hep, not for males
Raloxifene NI + contra liver dx, hx of blood clots, males, stop 3 days prior to
surgery
Alendronate + calcium inhibits bone reabsorbition, osteoporosis
salmon use + TE
alendronate SE esophagitis, GI upset, osteonecrosis of the jaw
alendronate contra + NI no oranges + caffiene, take in AM, for men, see dentist
Calcitonin- salmon SE naseau, nasal spray
2/
5
