1|Page
EVOLVE PHARMACOLOGY HESI LATEST 2025/ 2026 |
COMPLETE EXAM QUESTIONS WITH VERIFIED
DETAILED ANSWERS/ LATEST EXAM!!!
A client who has been taking phenazopyridine (Pyridium)
for symptoms of urethritis and cystitis comes to the clinic
because her urine is reddish-orange. Which question
should the practical nurse ask to determine if the
medication has been effective? - Answer-C) Have you had
any relief from urinary pain, burning, or urgency?
Feedback:
Phenazopyridine, an over-the-counter urinary analgesic,
acts on the mucosa of the urinary tract to relieve urinary
pain, burning, itching, or urgency (C) associated with
urethritis and cystitis. Although determining if the client is
forcing fluids (A), experiencing staining from Pyridium's
side effect (B), or having signs of a urinary infection (D)
are worthwhile assessments, the therapeutic response of
Pyridium is related to urinary discomforts only.
A male client who has been receiving an antineoplastic
drug has developed thrombocytopenia. What instructions
should the practical nurse (PN) reinforce? - Answer-D)
Shave with an electric razor.
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Feedback:
Thrombocytopenia is a common side effect of bone
marrow depression caused by several antineoplastic
agents. The client is experiencing a low platelet count and
should use an electric razor (D) to reduce his risk of
bleeding. (A, B, and C) are not indicated for a client who
needs to implement thrombocytopenia precautions.
The practical nurse (PN) is caring for a client who has
been taking prednisone (Deltasone) daily for a year. Which
adverse effect should the PN document in the client's
record? - Answer-B) Weight gain.
Feedback:
Long term use of prednisone causes fluid retention and
redistribution of fat deposition. Weight gain (B) and moon
face reflect adverse effects of long-term prednisone use
and should be documented. (A, C, and D) do not occur
with treatment using prednisone.
A female client with recurring headaches tells the practical
nurse (PN) that she has been taking at least 4 grams of
acetaminophen a day. Which laboratory studies should the
PN review for this client? - Answer-B) Hepatic enzymes.
Feedback:
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Liver toxicity can occur when doses of acetaminophen
exceed 4 grams a day, resulting in an elevation in hepatic
enzyme values (B). (A, C, and D) do not reveal findings
related to acetaminophen toxicity.
A client receives a prescription for an oral opioid analgesic
for post-operative pain. Which adverse effect should the
practical nurse (PN) monitor for with the client? - Answer-
A) Constipation.
Feedback:
Opioid analgesics slow peristalsis, which leads to
constipation (A), a common side effect of opiates. (B, C,
and D) are not associated with opioid analgesics.
Which action should the practical nurse implement when
administering a buccal medication? - Answer-D) Place the
medication between the upper molar teeth and cheek.
Feedback:
Buccal medications are placed between the upper molar
teeth and the cheek (D) for absorption by the capillaries of
the oral mucosa. The client should be cautioned against
swallowing, not (A). Buccal medications are not
administered with water (B). (C) describes sublingual
administration.
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What assessment is most important for the practical nurse
(PN) to obtain prior to initiating medication therapy with
phenelzine (Nardil) for a client with depression? - Answer-
C) Understanding of diet modification.
Feedback:
To prevent a potentially lethal hypertensive crisis, a
tyramine-free diet should be maintained during
antidepressant therapy with Nardil, a monoamine oxidase
inhibitor (MAOI). It is most important to determine if the
client understands diet modification (C) before Nardil is
initiated to prevent consumption of foods that interact with
Nardil. Although a client's activity level (A) and mood and
affect (B) should be monitored during antidepressant
therapy, it is most important that the client understand diet
modifications. The client's support system (D) and network
of family and friends is important, but the client should
understand the responsibility of dietary compliance with
the medication regimen.
The practical nurse (PN) is unable to arouse a client who
is receiving meperidine (Demerol) for postoperative pain.
The client is stuporous, has constricted pupils, and a
respiratory rate of 8 breaths/minute. Which PRN
EVOLVE PHARMACOLOGY HESI LATEST 2025/ 2026 |
COMPLETE EXAM QUESTIONS WITH VERIFIED
DETAILED ANSWERS/ LATEST EXAM!!!
A client who has been taking phenazopyridine (Pyridium)
for symptoms of urethritis and cystitis comes to the clinic
because her urine is reddish-orange. Which question
should the practical nurse ask to determine if the
medication has been effective? - Answer-C) Have you had
any relief from urinary pain, burning, or urgency?
Feedback:
Phenazopyridine, an over-the-counter urinary analgesic,
acts on the mucosa of the urinary tract to relieve urinary
pain, burning, itching, or urgency (C) associated with
urethritis and cystitis. Although determining if the client is
forcing fluids (A), experiencing staining from Pyridium's
side effect (B), or having signs of a urinary infection (D)
are worthwhile assessments, the therapeutic response of
Pyridium is related to urinary discomforts only.
A male client who has been receiving an antineoplastic
drug has developed thrombocytopenia. What instructions
should the practical nurse (PN) reinforce? - Answer-D)
Shave with an electric razor.
,2|Page
Feedback:
Thrombocytopenia is a common side effect of bone
marrow depression caused by several antineoplastic
agents. The client is experiencing a low platelet count and
should use an electric razor (D) to reduce his risk of
bleeding. (A, B, and C) are not indicated for a client who
needs to implement thrombocytopenia precautions.
The practical nurse (PN) is caring for a client who has
been taking prednisone (Deltasone) daily for a year. Which
adverse effect should the PN document in the client's
record? - Answer-B) Weight gain.
Feedback:
Long term use of prednisone causes fluid retention and
redistribution of fat deposition. Weight gain (B) and moon
face reflect adverse effects of long-term prednisone use
and should be documented. (A, C, and D) do not occur
with treatment using prednisone.
A female client with recurring headaches tells the practical
nurse (PN) that she has been taking at least 4 grams of
acetaminophen a day. Which laboratory studies should the
PN review for this client? - Answer-B) Hepatic enzymes.
Feedback:
,3|Page
Liver toxicity can occur when doses of acetaminophen
exceed 4 grams a day, resulting in an elevation in hepatic
enzyme values (B). (A, C, and D) do not reveal findings
related to acetaminophen toxicity.
A client receives a prescription for an oral opioid analgesic
for post-operative pain. Which adverse effect should the
practical nurse (PN) monitor for with the client? - Answer-
A) Constipation.
Feedback:
Opioid analgesics slow peristalsis, which leads to
constipation (A), a common side effect of opiates. (B, C,
and D) are not associated with opioid analgesics.
Which action should the practical nurse implement when
administering a buccal medication? - Answer-D) Place the
medication between the upper molar teeth and cheek.
Feedback:
Buccal medications are placed between the upper molar
teeth and the cheek (D) for absorption by the capillaries of
the oral mucosa. The client should be cautioned against
swallowing, not (A). Buccal medications are not
administered with water (B). (C) describes sublingual
administration.
, 4|Page
What assessment is most important for the practical nurse
(PN) to obtain prior to initiating medication therapy with
phenelzine (Nardil) for a client with depression? - Answer-
C) Understanding of diet modification.
Feedback:
To prevent a potentially lethal hypertensive crisis, a
tyramine-free diet should be maintained during
antidepressant therapy with Nardil, a monoamine oxidase
inhibitor (MAOI). It is most important to determine if the
client understands diet modification (C) before Nardil is
initiated to prevent consumption of foods that interact with
Nardil. Although a client's activity level (A) and mood and
affect (B) should be monitored during antidepressant
therapy, it is most important that the client understand diet
modifications. The client's support system (D) and network
of family and friends is important, but the client should
understand the responsibility of dietary compliance with
the medication regimen.
The practical nurse (PN) is unable to arouse a client who
is receiving meperidine (Demerol) for postoperative pain.
The client is stuporous, has constricted pupils, and a
respiratory rate of 8 breaths/minute. Which PRN
