Questions and Answers A+ Graded
(2025)
Which .of .the .following .statements .is .not .true .about .receptors? .- .CORRECT
.ANSWER-Receptors .are .located .in .CNS .fluid.
On .occasion, .drugs .can .be .prescribed .for .their .side .effects. .Which .of .the
.following .OTC .drugs .is .a .good .example .of .using .the .side .effect .of .sedation .for
.therapeutic .use? .- .CORRECT .ANSWER-antihistamines
The .first .main .phase .of .the .pharmacokinetic .process .is .- .CORRECT .ANSWER-
absorption .of .drug .into .bloodstream
A .common .mechanism .in .which .a .substance .can .interact .with .a .drug .is .by
.inducing .the .enzymes .that .metabolize .the .drug. .A .common .enzyme .is .known
.by .which .of .the .following .names? .- .CORRECT .ANSWER-cytochrome .P-450
What .is .the .mathematical .method .of .describing .the .process .of .absorption,
.distribution, .metabolism, .and .elimination .of .a .drug? .- .CORRECT .ANSWER-
pharmacokinetic .modeling
Which .of .the .following .statements .best .describes .bioavailability? .- .CORRECT
.ANSWER-the .fraction .of .an .administered .dose .that .is .available .to .the .target
.tissue
How .can .the .length .of .time .required .to .achieve .a .drug's .therapeutic .level .be
.shortened? .- .CORRECT .ANSWER-Administer .a .loading .dose
What .is .the .elimination .process .of .most .drugs .in .which .a .constant .fraction .of
.the .drug .is .eliminated .per .unit .of .time? .- .CORRECT .ANSWER-first-order
What .term .is .used .to .describe .a .drug .which .binds .to .a .receptor .and .has .an
.action .similar .to .that .of .an .endogenous .chemical? .- .CORRECT .ANSWER-
agonist
, In .what .way .are .the .capillaries .in .the .central .nervous .system .(CNS) .different
.from .other .capillaries? .- .CORRECT .ANSWER-They .are .enveloped .by .glial .cells,
.which .are .additional .barriers .against .water-soluble .compounds.
What .term .is .used .to .describe .the .study .of .drugs .on .living .systems? .-
.CORRECT .ANSWER-pharmacology
An .all-inclusive .effect .on .the .whole .body .is .also .called .a(n) ._____ .effect. .-
.CORRECT .ANSWER-systemic
Metabolism .is .the .process .in .which .drugs .are .converted .to .other .compounds
.and .then .they .are .- .CORRECT .ANSWER-Excreted
Which .of .the .following .terms .is .used .to .describe .a .severe .response .to .a
.chemical .that .is .characterized .by .life-threatening .respiratory .distress .and
.shock? .- .CORRECT .ANSWER-anaphylactic .reaction
Which .of .the .following .is .the .medical .term .for .an .itching .sensation? .-
.CORRECT .ANSWER-pruritus
What .is .an .unusual .or .unexpected .response .to .a .drug .that .is .unrelated .to .the
.dose .given? .- .CORRECT .ANSWER-idiosyncratic .reaction
Which .of .the .following .terms .describes .the .stability .of .the .organism? .-
.CORRECT .ANSWER-homeostasis
By .what .process .can .one .drug .increase .the .metabolism .of .both .itself .and .other
.drugs? .- .CORRECT .ANSWER-induction
A .drug's .clearance .is .important .for .determining .the .- .CORRECT .ANSWER-
maintenance .dose
How .does .grapefruit .juice .interact .with .certain .drugs? .- .CORRECT .ANSWER-It
.contains .a .compound .that .can .inhibit .intestinal .cytochrome .P-450, .allowing
.more .drug .to .be .absorbed .into .the .bloodstream.
What .term .is .used .to .describe .a .drug .produced .by .recombinant .DNA
.technology? .- .CORRECT .ANSWER-bioengineered
What .is .the .best .example .of .a .drug .that .is .eliminated .by .a .zero-order
.pharmacokinetic .process? .- .CORRECT .ANSWER-Alcohol
A .drug .prescribed .to .prevent .the .occurrence .of .an .infection .or .disease .is
.referred .to .as .a(n) .- .CORRECT .ANSWER-prophylactic .drug
Which .route .of .administration .does .not .require .absorption? .- .CORRECT
.ANSWER-Intravenous