8/26/25, 8:00
AM
NURS - 352 PHARMACOLOGY UNIT 2 EXAM
QUESTIONS AND ANSWERS WITH COMPLETE
SOLUTIONS LATEST UPDATE 2025/2026
Terms in this set (187)
Most disturbances of the Over secretion of acid, Alteration in GI
GI tract involve mucosa (inflammation or ulceration),
Alteration in GI peristalsis (diarrhea or
constipation), Nausea and vomiting
Peptic Ulcer Disease H. pylori, Gastric Acid Overproduction, NSAIDs,
(PUD) causes Smoking
- Antibiotics (only for H.Pylori)
- Anti-secretory Agents:
- H2 Blockers
Drug classes for PUD - PPIs
treatment
- Mucosal Protectants
- Antacids
Drug Class: Antibiotics for Triple-Therapy: 2 Antibiotics and a PPI
PUD
Drug Class: Anti-secretory H2 Blockers, PPIs
Agents
H2 Blockers MOA blocks H2 receptors in stomach
reducing acid secretions, volume, and pH level
H2 Blockers used for Hypersecretion of gastric acid, Gastric and
duodenal ulcers, Prophylaxis for stress ulcers,
1/
15
, 8/26/25, 8:00
AM
Gastro-esophageal Reflux Disease (GERD)
Drug Class: Anti-secretory Cimetidine*
Agents (H2 Blockers) (Tagamet)
famotidine
(Pepcid)
Take with water
May be taken with meals (To slow absorption)
Eliminate the use of substances that increase acid
production
- Smoking
H2 Blocker Education
- Spicy or fatty foods
- Emotional & physical stress
- Alcohol
Symptom relief
may take days
Ulcer healing may
take 4-8 weeks
Antacids decrease absorption (Take an hour apart)
Crosses the BBB
inhibits hepatic metabolism of the following drugs
- warfarin
H2 blockers adverse
- phenytoin
effects
- theophylline
- lidocaine
PPI (Proton Pump Inhibitor) Block the H+/K+ ATPase in the parietal cells preventing
MOA the generation of gastric acid
Hypersecretion of gastric acid, Gastric and
duodenal ulcers, Prophylaxis for stress ulcers,
2/
15
AM
NURS - 352 PHARMACOLOGY UNIT 2 EXAM
QUESTIONS AND ANSWERS WITH COMPLETE
SOLUTIONS LATEST UPDATE 2025/2026
Terms in this set (187)
Most disturbances of the Over secretion of acid, Alteration in GI
GI tract involve mucosa (inflammation or ulceration),
Alteration in GI peristalsis (diarrhea or
constipation), Nausea and vomiting
Peptic Ulcer Disease H. pylori, Gastric Acid Overproduction, NSAIDs,
(PUD) causes Smoking
- Antibiotics (only for H.Pylori)
- Anti-secretory Agents:
- H2 Blockers
Drug classes for PUD - PPIs
treatment
- Mucosal Protectants
- Antacids
Drug Class: Antibiotics for Triple-Therapy: 2 Antibiotics and a PPI
PUD
Drug Class: Anti-secretory H2 Blockers, PPIs
Agents
H2 Blockers MOA blocks H2 receptors in stomach
reducing acid secretions, volume, and pH level
H2 Blockers used for Hypersecretion of gastric acid, Gastric and
duodenal ulcers, Prophylaxis for stress ulcers,
1/
15
, 8/26/25, 8:00
AM
Gastro-esophageal Reflux Disease (GERD)
Drug Class: Anti-secretory Cimetidine*
Agents (H2 Blockers) (Tagamet)
famotidine
(Pepcid)
Take with water
May be taken with meals (To slow absorption)
Eliminate the use of substances that increase acid
production
- Smoking
H2 Blocker Education
- Spicy or fatty foods
- Emotional & physical stress
- Alcohol
Symptom relief
may take days
Ulcer healing may
take 4-8 weeks
Antacids decrease absorption (Take an hour apart)
Crosses the BBB
inhibits hepatic metabolism of the following drugs
- warfarin
H2 blockers adverse
- phenytoin
effects
- theophylline
- lidocaine
PPI (Proton Pump Inhibitor) Block the H+/K+ ATPase in the parietal cells preventing
MOA the generation of gastric acid
Hypersecretion of gastric acid, Gastric and
duodenal ulcers, Prophylaxis for stress ulcers,
2/
15
