Midterm Exam: NR565/ NR 565 Advanced Pharmacology Care
Study online at https://quizlet.com/_ff4b39
1. Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with
greater risk for those with diabetes and a risk score >7.5%: ASCVD Risk Score
2. Can be used in pregnancy/breastfeeding, as monotherapy or adjunct ther-
apy with a statin or fibrate: Ezetimibe Use
3. Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreas-
ing absorption from the small intestine, without affecting triglycerides: Eze-
timibe
4. Non-drug measures to lower LDL, including diet, exercise, weight control,
and smoking cessation: Lifestyle Changes for High Cholesterol
5. Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for
generally well-tolerated side effects: Minimizing Side Effects
6. Direct relaxant effect on vascular smooth muscles, dilation of coronary
vessels, reduction of preload and afterload, and promotion of vasodilation-
: Organic Nitrates Therapeutic Action
7. Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes,
including grapefruit juice, HIV protease inhibitors, macrolide antibiotics, azole
antifungal drugs, and some CCB: Ranolazine Contraindications
8. Avoid in children under 10: Statin Prescription Age
9. Promotes relaxation of coronary artery spasm, increasing cardiac oxygen
supply: CCB Role in Variant Angina
10. Aldosterone antagonist that promotes myocardial remodeling and fibrosis
to help with symptoms: HF Worsening Symptoms Medication
11. Promotes relaxation of peripheral arterioles, decreasing afterload and
reducing cardiac oxygen demand: CCB Stable Angina
12. Prescribe a BB to help with increased heart rate: Nitro Patches Side Effect
Response
13. When not used correctly, they lead to increased side effects, adverse
reactions, and toxicity: CYP450 Inhibitors and Reducers
14. In patients with infrequent flareups (less than three per year), NSAIDs are
the first line agent for relieving pain: Gouty Arthritis Treatment Decision
15. Prescribe a glucocorticoid (prednisone) or make dietary changes: Gouty
Arthritis NSAID Ineffectiveness
16. Considered for long term treatment if a person has three or more gouty
attacks per year: Colchicine Long Term Treatment
17. Should not be taken with statins or CYP3A4 inhibitors: Colchicine Con-
traindications
18. Nausea, vomiting, diarrhea, myelosuppression, myopathy, and rhabdomy-
olysis: Colchicine Adverse Effects
1/5
, Midterm Exam: NR565/ NR 565 Advanced Pharmacology Care
Study online at https://quizlet.com/_ff4b39
19. Can lead to severe cutaneous adverse reaction (SCAR) with symptoms like
rash, fever, eosinophilia, and liver and kidney function issues: Allopurinol Long
Term Effect
20. Should be co-administered with NSAIDs or colchicine: Febuxostat Co-Ad-
ministration
21. Erosion and irreversible joint damage, renal damage, and tophi formation-
: Untreated Gout Complications
22. Minimize risk of esophagitis by swallowing the pill whole with a full glass
of water, then sitting up for at least 30 min, and taking the med 30 min prior to
other intake: Alendronate Patient Education
23. Interferes with calcium, magnesium, and iron absorption: Ibandronate Di-
etary Supplement Interference
24. Alendronate is the first line treatment: Osteoporosis 1st Line Treatment
25. Safe to use in patients with renal dysfunction or who over produce uric
acid: Allopurinol Safety in Renal Dysfunction
26. Includes CBC with WBC differential, s/s of infection, malignancies, preg-
nancy rule out, ALT, AST, serum creatinine, comprehensive history and phys-
ical exam, and assessment of immunocompetence and liver and renal status-
: DMARDs Baseline Diagnostics
27. Includes chest x-ray with emphasis on pulmonary and GI status: Methotrex-
ate Baseline Data
28. Hydroxychloroquine: DMARD Requiring Ophthalmologic and Cardiac Exam
29. Risk for venous thromboembolic events (DVT, PE, stroke): Raloxifene Black
Box Warning
30. Reinforcing properties of drugs, physical and physiological dependence,
social factors, drug availability, individual vulnerability, impulsivity, low toler-
ance for frustration, and specific personality disorders: Controlled Substance
Addiction Predictors
31. Adjuvant analgesic for neuropathic pain, effective in diabetic neuropathy,
seizures, central neuropathy, postherpetic neuralgia, and fibromyalgia: Prega-
balin Chronic Pain Treatment
32. Sedation, drowsiness, dizziness, ataxia, blurred vision, and difficulty think-
ing: Pregabalin Adverse Effects
33. Linked to COX-2 inhibitors and NSAIDs: GI Bleeding Link
34. Start taking this medicine at the first sign of the attack for best results,
stop taking this medicine as soon as the pain is relieved or at the first sign of
nausea, vomiting, stomach pain, or diarrhea: Colchicine Patient Education
35. Methotrexate, leflunomide, and biologics like anti-TNF agents, rituximab,
and abatacept: RA High Risk Drugs in Pregnancy
2/5
Study online at https://quizlet.com/_ff4b39
1. Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with
greater risk for those with diabetes and a risk score >7.5%: ASCVD Risk Score
2. Can be used in pregnancy/breastfeeding, as monotherapy or adjunct ther-
apy with a statin or fibrate: Ezetimibe Use
3. Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreas-
ing absorption from the small intestine, without affecting triglycerides: Eze-
timibe
4. Non-drug measures to lower LDL, including diet, exercise, weight control,
and smoking cessation: Lifestyle Changes for High Cholesterol
5. Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for
generally well-tolerated side effects: Minimizing Side Effects
6. Direct relaxant effect on vascular smooth muscles, dilation of coronary
vessels, reduction of preload and afterload, and promotion of vasodilation-
: Organic Nitrates Therapeutic Action
7. Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes,
including grapefruit juice, HIV protease inhibitors, macrolide antibiotics, azole
antifungal drugs, and some CCB: Ranolazine Contraindications
8. Avoid in children under 10: Statin Prescription Age
9. Promotes relaxation of coronary artery spasm, increasing cardiac oxygen
supply: CCB Role in Variant Angina
10. Aldosterone antagonist that promotes myocardial remodeling and fibrosis
to help with symptoms: HF Worsening Symptoms Medication
11. Promotes relaxation of peripheral arterioles, decreasing afterload and
reducing cardiac oxygen demand: CCB Stable Angina
12. Prescribe a BB to help with increased heart rate: Nitro Patches Side Effect
Response
13. When not used correctly, they lead to increased side effects, adverse
reactions, and toxicity: CYP450 Inhibitors and Reducers
14. In patients with infrequent flareups (less than three per year), NSAIDs are
the first line agent for relieving pain: Gouty Arthritis Treatment Decision
15. Prescribe a glucocorticoid (prednisone) or make dietary changes: Gouty
Arthritis NSAID Ineffectiveness
16. Considered for long term treatment if a person has three or more gouty
attacks per year: Colchicine Long Term Treatment
17. Should not be taken with statins or CYP3A4 inhibitors: Colchicine Con-
traindications
18. Nausea, vomiting, diarrhea, myelosuppression, myopathy, and rhabdomy-
olysis: Colchicine Adverse Effects
1/5
, Midterm Exam: NR565/ NR 565 Advanced Pharmacology Care
Study online at https://quizlet.com/_ff4b39
19. Can lead to severe cutaneous adverse reaction (SCAR) with symptoms like
rash, fever, eosinophilia, and liver and kidney function issues: Allopurinol Long
Term Effect
20. Should be co-administered with NSAIDs or colchicine: Febuxostat Co-Ad-
ministration
21. Erosion and irreversible joint damage, renal damage, and tophi formation-
: Untreated Gout Complications
22. Minimize risk of esophagitis by swallowing the pill whole with a full glass
of water, then sitting up for at least 30 min, and taking the med 30 min prior to
other intake: Alendronate Patient Education
23. Interferes with calcium, magnesium, and iron absorption: Ibandronate Di-
etary Supplement Interference
24. Alendronate is the first line treatment: Osteoporosis 1st Line Treatment
25. Safe to use in patients with renal dysfunction or who over produce uric
acid: Allopurinol Safety in Renal Dysfunction
26. Includes CBC with WBC differential, s/s of infection, malignancies, preg-
nancy rule out, ALT, AST, serum creatinine, comprehensive history and phys-
ical exam, and assessment of immunocompetence and liver and renal status-
: DMARDs Baseline Diagnostics
27. Includes chest x-ray with emphasis on pulmonary and GI status: Methotrex-
ate Baseline Data
28. Hydroxychloroquine: DMARD Requiring Ophthalmologic and Cardiac Exam
29. Risk for venous thromboembolic events (DVT, PE, stroke): Raloxifene Black
Box Warning
30. Reinforcing properties of drugs, physical and physiological dependence,
social factors, drug availability, individual vulnerability, impulsivity, low toler-
ance for frustration, and specific personality disorders: Controlled Substance
Addiction Predictors
31. Adjuvant analgesic for neuropathic pain, effective in diabetic neuropathy,
seizures, central neuropathy, postherpetic neuralgia, and fibromyalgia: Prega-
balin Chronic Pain Treatment
32. Sedation, drowsiness, dizziness, ataxia, blurred vision, and difficulty think-
ing: Pregabalin Adverse Effects
33. Linked to COX-2 inhibitors and NSAIDs: GI Bleeding Link
34. Start taking this medicine at the first sign of the attack for best results,
stop taking this medicine as soon as the pain is relieved or at the first sign of
nausea, vomiting, stomach pain, or diarrhea: Colchicine Patient Education
35. Methotrexate, leflunomide, and biologics like anti-TNF agents, rituximab,
and abatacept: RA High Risk Drugs in Pregnancy
2/5
