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A 12-year-old Caucasian male patient with a history of asthma is
homozygous for the T2206C variant of FCER2. He is currently on
medium dose inhaled corticosteroid in combination with a LABA, as
needed SABA and daily montelukast. His serum eosinophils are
currently 400/µL. According to the data discussed in class, which of
the following treatment steps should be considered as a 'next
step'? Increase ICS to high dose
Discontinue montelukast
Add omalizumab or mepolizumab
Add theophylline
Give this one a try later!
Gln/Glu Add continuous infusion
at amino acid position 27
aminophylline
The parents should fill the
Add omalizumab
prescription for corticosteroids. This
or mepolizumab
patient is likely to have a good
response to daily ICS.
Don't know?
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