TEST BANK FOR HARRISON S PRINCIPLES OF INTERNAL MEDICINE SELF ASSESSMENT EXAM TEST WITH LATEST UPDATED (QUESTIONS AND ANSWERS)

TEST BANK FOR HARRISON S PRINCIPLES
OF INTERNAL MEDICINE SELF ASSESSMENT
EXAM TEST WITH LATEST UPDATED
(QUESTIONS AND ANSWERS)
Paroxysmal Cold Hemoglobinuria - ANSWER: A rare condition in children triggered
by viral infection, leading to self-limited hemolysis

6-Phosphate Dehydrogenase (G6PD) Gene - ANSWER: A mutation in this gene
causes G6PD deficiency, resulting in hemolysis when exposed to certain drugs

Septicemia - ANSWER: A condition identified by blood cultures, contributing to
intravascular hemolysis

Paroxysmal Nocturnal Hemoglobinuria (PNH) - ANSWER: Causes sudden and
severe hemoglobinuria within hours

Bite Cells - ANSWER: Abnormal cells seen in peripheral blood smear, indicating
G6PD deficiency

Anisocytosis - ANSWER: Abnormal variation in the size of red blood cells, indicative
of G6PD deficiency

Spherocytes - ANSWER: Abnormally round red blood cells seen in peripheral blood
smear, indicative of G6PD deficiency

Hemoglobinemia - ANSWER: The presence of free hemoglobin in the blood, leading
to jaundice and dark urine during a hemolytic attack

Hemoglobinuria - ANSWER: The presence of hemoglobin in the urine, leading to
jaundice and dark urine during a hemolytic attack

Lactate Dehydrogenase - ANSWER: An enzyme elevated in hemolytic attacks,
indicative of G6PD deficiency

Haptoglobin - ANSWER: A protein that is low or absent in hemolytic attacks,
indicative of G6PD deficiency #$%^&*&
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Autoimmune Hemolytic Anemia (AIHA) - ANSWER: Caused by warm IgG antibodies (*&^%^&
due to drug exposure, with a mortality rate of approximately 10%
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Direct Antiglobulin (Coombs) Test - ANSWER: A diagnostic test for AIHA, detecting (*&^%%^
antibodies on red blood cells &*()(*&^
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Rituximab - ANSWER: A second-line treatment for AIHA, reducing the rate of relapse ^%^&*(*
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