r
,Chapterr01:rIntroductionrtorPathophysiology
VanMeterrandrHubert:rGould’srPathophysiologyrforrtherHealthrProfessions,r7thrEdition
MULTIPLErCHOICE
1. Whichrofrtherfollowingrwouldrberthermostrlikelyrcauserofranria
trogenicrdisease?
a. Anrinheritedrdisorder
b. Arcombinationrofrspecificretiologicalrfactors
c. Anrunwantedreffectrofrarprescribedrdrug
d. Prolongedrexposurertortoxicrchemicalsrinrtherenvironment
ANS:r C
2. Thermanifestationsrofrardiseaserarerbestrdefinedrasrthe
a. subjectiverfeelingsrofrdiscomfortrduringrarchronicrillness.
b. signsrandrsymptomsrofrardisease.
c. factorsrthatrprecipitateranracuterepisoderofrarchronicrillness.
d. earlyrindicatorsrofrtherprodromalrstagerofrinfection.
ANS:r B
3. Therbestrdefinitionrofrthertermrprognosisrisrthe
a. precipitatingrfactorsrcausingranracuterepisode.
b. numberrofrremissionsrtorberexpectedrduringrthercourserofrarchronicrillness.
c. predictedroutcomerorrlikelihoodrofrrecoveryrfromrarspecificrdisease.
d. exacerbationsroccurringrduringrchronicrillness.
ANS:r C
4. Whichrofrtherfollowingrisrconsideredrarsystemicrsignrofrdisease?
a. Swellingrofrtherknee
b. Fever
c. Painrinrtherneck
d. Redrrashronrtherface
ANS:r B
5. Etiologyrisrdefinedrasrtherstudyrofrthe
a. causesrofrardisease.
b. courserofrardisease.
c. expectedrcomplicationsrofrardisease.
d. manifestationsrofrardisease.
ANS:r A
6. Artyperofrcellularradaptationrinrwhichrthererisrardecreaserinrcellrsizerisrreferredrtoras
a. hypertrophy.
b. metaplasia.
c. anaplasia.
d. atrophy.
ANS:r D
7. Archangerinrartissuermarkedrbyrcellsrthatrvaryrinrsizerandrshaperandrshowrincreasedrmitoticrfig
uresrwouldrbercalled
, a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS:r C
8. Ardeficitrofroxygenrinrthercellsrusuallyrduertorrespiratoryrorrcirculatoryrproblemsrisrcalled
a. apoptosis.
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS:r B
9. Whenrargrouprofrcellsrinrtherbodyrdies,rtherchangerisrcalled
a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS:r D
10. Rigorousrweightlifting/bodyrbuildingrregimensrmayrresultrinrtherskeletalrmusclercellsru
ndergoing
a. hypertrophy.
b. dysplasia.
c. atrophy.
d. regeneration.
ANS:r A
11. Thertermrcancerrrefersrto
a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignantrneoplasm.
ANS:r D
12. Torwhichrofrtherfollowingrdoesrthertermrapoptosisrrefer?
a. Increasedrraterofrmitosisrbyrcertainrcells
b. Ischemicrdamagertorcells
c. Liquefactionrofrnecroticrtissue
d. Preprogrammedrcellrself-destruction
ANS:r D
13. WhichrofrtherfollowingrstatementsrisrTRUE?
a. AlterationrofrDNArdoesrnotrchangercellrfunction.
b. Damagedrcellsrmayrberablertorrepairrthemselves.
c. Allrtypesrofrcellsrdieratrthersamerrate.
d. Mildrischemiarcausesrimmediatercellrdeath.
ANS:r B
14. Caseationrnecrosisrrefersrtoranrarearwhere
a. cellrproteinsrhaverbeenrdenatured.
, b. cellsrarerliquefiedrbyrenzymes.
c. deadrcellsrformrarthickrcheesyrsubstance.
d. bacterialrinvasionrhasroccurred.
ANS:r C
15. Routinerapplicationrofrsunrblockrtorskinrwouldrberanrexamplerof
a. anriatrogenicrcauserofrcancer.
b. arpreventivermeasure.
c. arprecipitatingrfactor.
d. arpredisposingrcondition.
ANS:r B
16. Arcircumstancerthatrcausesrarsuddenracuterepisoderofrarchronicrdiseasertoroccurrisrtermed
a. latentrstage.
b. predisposingrfactor.
c. incidence.
d. precipitatingrfactor.
ANS:r D
17. Thertermrhomeostasisrrefersrto
a. thercausativerfactorsrinrarparticularrdisease.
b. maintenancerofrarstablerinternalrenvironment.
c. arconditionrthatrtriggersranracuterepisode.
d. arcollectionrofrsignsrandrsymptoms.
ANS:r B
18. Whichrtermrisrusedrtordescriberarnewrandrsecondaryrorradditionalrproblemrthatrarisesrafterrtherori
ginalrdiseaserhasrbeenrestablished?
a. Symptoms
b. Occurrence
c. Manifestations
d. Complication
ANS:r D
19. Pathophysiologyrinvolvesrtherstudyrof
a. therstructurerofrtherhumanrbody.
b. therfunctionsrofrvariousrorgansrinrtherbody.
c. functionalrorrstructuralrchangesrresultingrfromrdiseaserprocesses.
d. variousrcellrstructuresrandrrelatedrfunctions.
ANS:r C
20. Whichrofrtherfollowingrisrtherbestrdefinitionrofrepidemiology?
a. Thersciencerofrtrackingrtheroccurrencerandrdistributionrofrdiseases
b. Therrelativernumberrofrdeathsrresultingrfromrarparticularrdisease
c. Identificationrofrarspecificrdiseaserthroughrevaluationrofrsignsrandrsymptoms
d. Therglobalrsearchrforremergingrdiseases
ANS:r A