Drug Class : ACE Inhibitor ( Angiotensin Converting Enzyme Inhibitors)
ACE Inhibitors basically reduces the peripheral resistance and
work load (preload and afterload).
Examples:
• Captopril
• Enalapril
• Lisinopril
Mechanism Of Action:
• Inhibits the ACE, enzyme that converts the Angiotensin Ⅰà
Angiotensin Ⅱ.
• Low Angiotensin Ⅱ means less vasoconstriction.
• Less amount of aldosterone secretion.
• Leads to low blood pressure and blood volume.
Adverse Effects:
Mnemonic: CAPT
• Cough( dry, persistent )
• Angioedema
• Proteinuria
• Taste change
Contradictions:
• Pregnancy
• History of Angioedema with ACE inhibitor
Clinical USES:
• Used to treat hypertension.
• Used to treat chronic heart failure(CHF).
ACE Inhibitors basically reduces the peripheral resistance and
work load (preload and afterload).
Examples:
• Captopril
• Enalapril
• Lisinopril
Mechanism Of Action:
• Inhibits the ACE, enzyme that converts the Angiotensin Ⅰà
Angiotensin Ⅱ.
• Low Angiotensin Ⅱ means less vasoconstriction.
• Less amount of aldosterone secretion.
• Leads to low blood pressure and blood volume.
Adverse Effects:
Mnemonic: CAPT
• Cough( dry, persistent )
• Angioedema
• Proteinuria
• Taste change
Contradictions:
• Pregnancy
• History of Angioedema with ACE inhibitor
Clinical USES:
• Used to treat hypertension.
• Used to treat chronic heart failure(CHF).
