Bio 325
BIO 325- Genetics Fischer Final Exam 2025
__________ is the basic unit of inheritance
gene
What are examples of a pure breeding line?
-A population of short plants whose parents were all short
-A population of tall plants with purple flowers that have produced the same
phenotype for several generations
Transgenic mice can be created by injecting DNA into __________ of a zygote
one pronucleus
The DNA that is injected may ____________ so that there are many tandem
copies.
concatamerize
The injected DNA integrates into the host chromosome at a __________ site
random
The injected zygote is placed into a ____________ ___________
receptive female
The pups that are whelped are tested by examining DNA isolated from a piece of
their _______
tail
Researchers create reproductive clones-- how?
somatic cell nuclear transfer
Huntington disease is caused by a dominant allele of the ______ with an expanded
number of ____________ repeats within the coding region.
HD gene; CAG triplet
Bio 325
, Bio 325
Transgenic farm animals and plants can provide a _______-________ and _____-
_______ alternative to cell culture for producing human proteins.
cost-effective; high-yield
Proteins produced in transgenic animals can be useful for ________ ___________.
Medical purposes
Bacterial proteins produced in plants can be useful as ________.
vaccines
The term __________ refers to the use of transgenic farm animals to produce
therapeutically useful proteins
pharming
One reason transgenic farm animals are used for producing proteins of therapeutic
use is the _______ __________ of protein that can be produced.
large quantities
Rare transgenic animals that produce high levels of a useful protein can be
replicated most effectively by ___________ __________.
reproductive cloning
AAVs have _____-_______ DNA genomes that become _________-_________
after infection of host cells
single-stranded; double-straded
The defective double-stranded AAV genomes containing the therapeutic gene
usually do not integrate into the ____ ____ _________, through they can still
produce the therapy proteins.
host cell chromosomes
Currently most human gene therapy relies on the use of using ______ _______ to
introduce DNA into cells.
viral vectors
Bio 325
BIO 325- Genetics Fischer Final Exam 2025
__________ is the basic unit of inheritance
gene
What are examples of a pure breeding line?
-A population of short plants whose parents were all short
-A population of tall plants with purple flowers that have produced the same
phenotype for several generations
Transgenic mice can be created by injecting DNA into __________ of a zygote
one pronucleus
The DNA that is injected may ____________ so that there are many tandem
copies.
concatamerize
The injected DNA integrates into the host chromosome at a __________ site
random
The injected zygote is placed into a ____________ ___________
receptive female
The pups that are whelped are tested by examining DNA isolated from a piece of
their _______
tail
Researchers create reproductive clones-- how?
somatic cell nuclear transfer
Huntington disease is caused by a dominant allele of the ______ with an expanded
number of ____________ repeats within the coding region.
HD gene; CAG triplet
Bio 325
, Bio 325
Transgenic farm animals and plants can provide a _______-________ and _____-
_______ alternative to cell culture for producing human proteins.
cost-effective; high-yield
Proteins produced in transgenic animals can be useful for ________ ___________.
Medical purposes
Bacterial proteins produced in plants can be useful as ________.
vaccines
The term __________ refers to the use of transgenic farm animals to produce
therapeutically useful proteins
pharming
One reason transgenic farm animals are used for producing proteins of therapeutic
use is the _______ __________ of protein that can be produced.
large quantities
Rare transgenic animals that produce high levels of a useful protein can be
replicated most effectively by ___________ __________.
reproductive cloning
AAVs have _____-_______ DNA genomes that become _________-_________
after infection of host cells
single-stranded; double-straded
The defective double-stranded AAV genomes containing the therapeutic gene
usually do not integrate into the ____ ____ _________, through they can still
produce the therapy proteins.
host cell chromosomes
Currently most human gene therapy relies on the use of using ______ _______ to
introduce DNA into cells.
viral vectors
Bio 325
