COMSAE EXAM QUESTIONS AND ANSWERS
(COMSAE form D & 6/18/19)
drug for UC/Crohns - -sulfasalazine
-pulmonary effects of CF - -chronic bronchitis & bronchiectasis
-osteoporosis affects what parts of bone? - -(spongy and ) trabecular bone mass loss
-imipramine: Class, AE's? - -TCA
SE: Tri-Cs
convulsions
coma
cardiotox
antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension- block
alpha1)
-loratidine vs ranitidine - -loratidine: 2nd gen H1 blocker, doesnt cross BBB --> less
sedating
ranitidine: H2 receptor antagonist (like cimetidine)
-cells w RBCs inside - -entaemoba histolytica
-intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous tortuous
vessels - -AVM arteriovenous malformation
-cavernous hemangioma - -benign tumor of liver, A/W VHL
-anti-HepBs Ab= recovered or immunized - -
-proctalgia fugax - -levator ani syndrome
-fasciculus is UMN or LMN lesion? - -LMN
-ectopic gastric tissue - -meckels diverticulum
can also have ectopic pancreatic tissue
remnant of vitelline duct
, -antibodies in hashimotos attacks - -thyroid peroxidase or antithyroglobulin
enlarged non tender thyroid
-2 factors that influence starling curve - -x axis- preload (EDV)
y axis- stroke volume or CO
-treatment for fibromyalgia - -TCA, SNRIs anticonvulsants
-possible complication of pagets bone disease - -osteocarcoma
-what does Hct tell you? - -ratio of volume of RBCs compared to total blood volume
-probenecid - -inhibits reabsoprtion of uric acid in PCT
- also inhibits secretion of PCN
- can ppt uric acid calculi
-2 causes of SCID - -ADA deficiency
(adenosine deaminase required for degradation of adenosim and deoxyadenosine
- in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID
hypoplastic thymus
-lithiums effects on urination - -inhibits vasopression/ADH --> increased urinary
frequency
-infertility drug that can result in multiple fetuses - -clomiphene (clones- multiple babies)
antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback)
upregulates LH and FSH release from pituitary --> ovulation
used to treat PCOS but can cause ovarian enlargement, multiple fetuses
-tx for tinea - -azoles
-beta blockers for asthma - -none- even beta 1s can be nonselective at higher doses
-what kind of teratogenic effects are seen w ACE/ARBs - -fetal renal agenesis
-stones bones groans moans psych overtones - -high Ca or PTH
-PTH is made by what cells? Fx? - -chief cells of parathyroid gland
PO4- proximal tubule
ca- DCT
(COMSAE form D & 6/18/19)
drug for UC/Crohns - -sulfasalazine
-pulmonary effects of CF - -chronic bronchitis & bronchiectasis
-osteoporosis affects what parts of bone? - -(spongy and ) trabecular bone mass loss
-imipramine: Class, AE's? - -TCA
SE: Tri-Cs
convulsions
coma
cardiotox
antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension- block
alpha1)
-loratidine vs ranitidine - -loratidine: 2nd gen H1 blocker, doesnt cross BBB --> less
sedating
ranitidine: H2 receptor antagonist (like cimetidine)
-cells w RBCs inside - -entaemoba histolytica
-intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous tortuous
vessels - -AVM arteriovenous malformation
-cavernous hemangioma - -benign tumor of liver, A/W VHL
-anti-HepBs Ab= recovered or immunized - -
-proctalgia fugax - -levator ani syndrome
-fasciculus is UMN or LMN lesion? - -LMN
-ectopic gastric tissue - -meckels diverticulum
can also have ectopic pancreatic tissue
remnant of vitelline duct
, -antibodies in hashimotos attacks - -thyroid peroxidase or antithyroglobulin
enlarged non tender thyroid
-2 factors that influence starling curve - -x axis- preload (EDV)
y axis- stroke volume or CO
-treatment for fibromyalgia - -TCA, SNRIs anticonvulsants
-possible complication of pagets bone disease - -osteocarcoma
-what does Hct tell you? - -ratio of volume of RBCs compared to total blood volume
-probenecid - -inhibits reabsoprtion of uric acid in PCT
- also inhibits secretion of PCN
- can ppt uric acid calculi
-2 causes of SCID - -ADA deficiency
(adenosine deaminase required for degradation of adenosim and deoxyadenosine
- in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID
hypoplastic thymus
-lithiums effects on urination - -inhibits vasopression/ADH --> increased urinary
frequency
-infertility drug that can result in multiple fetuses - -clomiphene (clones- multiple babies)
antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback)
upregulates LH and FSH release from pituitary --> ovulation
used to treat PCOS but can cause ovarian enlargement, multiple fetuses
-tx for tinea - -azoles
-beta blockers for asthma - -none- even beta 1s can be nonselective at higher doses
-what kind of teratogenic effects are seen w ACE/ARBs - -fetal renal agenesis
-stones bones groans moans psych overtones - -high Ca or PTH
-PTH is made by what cells? Fx? - -chief cells of parathyroid gland
PO4- proximal tubule
ca- DCT
