PEDIATRIC COMAT EXAM STUDY
GUIDE NEWEST 2025/2026 WITH
QUESTIONS AND CORRECT ANSWERS |
ALREADY GRADED A+
increased unilateral tearing, clear conjunctiva, eye lash
crusting and fluorescein dye testing persisting and flowing
down eyelid Correct Answer NLD (nasolacrimal duct
obstruction) aka dacrostenosis
fluorescein dye testing showing discrete area of staining
Correct Answer corneal abrasion
bilateral clear eye discharge, ocular pruritis, eyelid edema,
and conjunctival injection Correct Answer allergic
conjunctivitis
purulent eye drainage, erythema, tenderness, swelling,
and warmth over lacrimal sac Correct Answer dacrocystitis
(infection of NLD)
bilateral cranial neuropathies and symmetric flaccid
paralysis leading to CO2 retention Correct Answer
botulism (preformed toxins in canned foods)
gram + spore forming anaerobic rod Correct Answer C
botulinum
,MOA of botulism Correct Answer prevents release of Ach
at NMJ
botulism tx Correct Answer equine serum heptavalent
botulinum antitoxin and supportive care
generalized muscle fatiguability that improves with rest
Correct Answer Myasthenia gravis
isolated protein concentration in CSF Correct Answer GBS
(Guillain barre syndrome)
ascending paralysis with decreased deep tendon reflexes
often following URI Correct Answer gullian barre
flaccid bullae with thick yellow fluid Correct Answer bullous
impetigo caused by staph aureus
cause of non bullous impetigo Correct Answer strep
pyogenes
bullous impetigo tx Correct Answer cephalexin
papules with honey crusted lesions Correct Answer non
bullous impetigo
non bullous impetigo tx Correct Answer topical muciprocin
Bullous Phemphigoid and pemphigus vulgaris tx Correct
Answer oral prednisone
,painless bloody stools around 2yo Correct Answer meckel
diverticulum
any number of joint abnormality, intermittent fevers,
anemia and pink macular rash that fades on
defervescence Correct Answer sJIA (systemic juvenile
idiopathic arthritis)
sJIA tx Correct Answer NSAIDs and methotrexate
refractory cases - IL1 and IL6 inhibitors
ANA and RF in sJIA Correct Answer negative both
less than 4 joint abnormality, asymmetric, involving large
weight bearing joints, and uveitis Correct Answer oJIA
(oligoarticular)
oJIA labs Correct Answer labs - positive ANA and
negative RF
less than 5 joint abnormalities in smaller joints, symmetric,
and uveitits Correct Answer pJIA (polyarticular juvenile
idiopathic arthritis)
pJIA labs Correct Answer labs - positive ANA and RF
conjunctivitis in first 24 hr life, 2-5 days and 5-14 days
causes Correct Answer 24 hr - chemical
2-5 days - gonococcal
5-14 - chlamydial
, chemical conjunctivitis tx Correct Answer supportive
gonococcal conjunctivitis tx Correct Answer ceftriaxone IV
chlamydial conjunctivitis tx Correct Answer oral
erythromycin
increased beta hCg and inhibin A and decreased AFP and
unconjugated estriol Correct Answer Down's
air-fluid level meaning Correct Answer SBO
pneumatosis intestinalis meaning Correct Answer
necrotizing enterocolitis
sentinel loop Correct Answer paralysis of intestinal motility
metabolic acidosis, hemolytic anemia, and increased
urinary 5-oxoproline Correct Answer glutathione
synthetase deficiency
glutathione synthetase deficiency tx Correct Answer
correct metabolic acidosis with sodium bicarb and long
term administration of antioxidants, vitamin C and E
deficiency of galactose 1 phosphate uridylytransferase
Correct Answer galactosemia (severe feeding intolerance
and lethargy after breast feeding)
deficiency in homogentisate oxidase Correct Answer
alkaptonuria (onchronosis, black urine, and arthritis)
GUIDE NEWEST 2025/2026 WITH
QUESTIONS AND CORRECT ANSWERS |
ALREADY GRADED A+
increased unilateral tearing, clear conjunctiva, eye lash
crusting and fluorescein dye testing persisting and flowing
down eyelid Correct Answer NLD (nasolacrimal duct
obstruction) aka dacrostenosis
fluorescein dye testing showing discrete area of staining
Correct Answer corneal abrasion
bilateral clear eye discharge, ocular pruritis, eyelid edema,
and conjunctival injection Correct Answer allergic
conjunctivitis
purulent eye drainage, erythema, tenderness, swelling,
and warmth over lacrimal sac Correct Answer dacrocystitis
(infection of NLD)
bilateral cranial neuropathies and symmetric flaccid
paralysis leading to CO2 retention Correct Answer
botulism (preformed toxins in canned foods)
gram + spore forming anaerobic rod Correct Answer C
botulinum
,MOA of botulism Correct Answer prevents release of Ach
at NMJ
botulism tx Correct Answer equine serum heptavalent
botulinum antitoxin and supportive care
generalized muscle fatiguability that improves with rest
Correct Answer Myasthenia gravis
isolated protein concentration in CSF Correct Answer GBS
(Guillain barre syndrome)
ascending paralysis with decreased deep tendon reflexes
often following URI Correct Answer gullian barre
flaccid bullae with thick yellow fluid Correct Answer bullous
impetigo caused by staph aureus
cause of non bullous impetigo Correct Answer strep
pyogenes
bullous impetigo tx Correct Answer cephalexin
papules with honey crusted lesions Correct Answer non
bullous impetigo
non bullous impetigo tx Correct Answer topical muciprocin
Bullous Phemphigoid and pemphigus vulgaris tx Correct
Answer oral prednisone
,painless bloody stools around 2yo Correct Answer meckel
diverticulum
any number of joint abnormality, intermittent fevers,
anemia and pink macular rash that fades on
defervescence Correct Answer sJIA (systemic juvenile
idiopathic arthritis)
sJIA tx Correct Answer NSAIDs and methotrexate
refractory cases - IL1 and IL6 inhibitors
ANA and RF in sJIA Correct Answer negative both
less than 4 joint abnormality, asymmetric, involving large
weight bearing joints, and uveitis Correct Answer oJIA
(oligoarticular)
oJIA labs Correct Answer labs - positive ANA and
negative RF
less than 5 joint abnormalities in smaller joints, symmetric,
and uveitits Correct Answer pJIA (polyarticular juvenile
idiopathic arthritis)
pJIA labs Correct Answer labs - positive ANA and RF
conjunctivitis in first 24 hr life, 2-5 days and 5-14 days
causes Correct Answer 24 hr - chemical
2-5 days - gonococcal
5-14 - chlamydial
, chemical conjunctivitis tx Correct Answer supportive
gonococcal conjunctivitis tx Correct Answer ceftriaxone IV
chlamydial conjunctivitis tx Correct Answer oral
erythromycin
increased beta hCg and inhibin A and decreased AFP and
unconjugated estriol Correct Answer Down's
air-fluid level meaning Correct Answer SBO
pneumatosis intestinalis meaning Correct Answer
necrotizing enterocolitis
sentinel loop Correct Answer paralysis of intestinal motility
metabolic acidosis, hemolytic anemia, and increased
urinary 5-oxoproline Correct Answer glutathione
synthetase deficiency
glutathione synthetase deficiency tx Correct Answer
correct metabolic acidosis with sodium bicarb and long
term administration of antioxidants, vitamin C and E
deficiency of galactose 1 phosphate uridylytransferase
Correct Answer galactosemia (severe feeding intolerance
and lethargy after breast feeding)
deficiency in homogentisate oxidase Correct Answer
alkaptonuria (onchronosis, black urine, and arthritis)
