CMN 568 Unit 3 2025 Complete Questions And
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What are the 3 characteristics of Asthma - (ANSWER)Bronchoconstriction
Airway Inflammation
Reversible airflow limitation
Which inhaled anticholinergic is best used for asthma pt. w/an intolerance to beta
agonist or w/ bronchospasms due to beta blocker meds? - (ANSWER)Ipratropium
Bromide
What is the primary tx for pt. w/moderate to severe asthma exacerbations who
do not respond promptly and completely to SABA? - (ANSWER)Systemic
Corticosteroids
Which bacterial infections predispose exacerbations of asthma - (ANSWER)M.
Pneumoniae and C. Pneumoniae
Is routine use of antimicrobials recommended for acute exacerbations of asthma -
(ANSWER)No, only use when likelihood of acute bacterial respiratory tract
infection
Name short acting beta agonist - (ANSWER)albuterol, levalbuterol, bitolerol,
pirbuterol, terbutaline
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What does a SABA do? - (ANSWER)acts directly by relaxing bronchial smooth
muscles.
What do long-term pharmacologic agents accomplish for asthma pt. -
(ANSWER)act primarily to attenuate airway inflammation.
Why take long-term pharmacologic agents for asthma daily? - (ANSWER)to
achieve and maintain control of persistent asthma independent of symptoms.
What does the NAEPP recommend as the cornerstone of daily treatment of
persistent asthma? - (ANSWER)daily anti-inflammatory therapy with inhaled
corticosteroids
Role of corticosteroids with asthma - (ANSWER)Reduce inflammation (acute and
chronic) = improved airflow, decreased airway hyper-responsiveness and fewer
asthma exacerbations, and potentiate the action of beta-adrenergic agonist.
1st. line treatment agent for all pt w/persistent asthma (long term controller) -
(ANSWER)Inhaled Corticosteroids
How often to most patient use inhaled corticosteroids? - (ANSWER)Twice daily to
provide adequate control.
How long can it take to see maximum response of inhaled corticosterioids? -
(ANSWER)Months
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What can a patient do to reduce side effects of inhaled corticosteroids? -
(ANSWER)Rinse mouth after each use
A patient has an exacerbation of asthma, what is the most effective treatment to
achieve prompt control? - (ANSWER)Systemic (oral) corticosteroids
Dose of oral corticosteroids for children during exacerbation of asthma -
(ANSWER)1-2 mg/kg/day.
Can be either a single dose or divided BID.
MAX 60 mg/day
Dose of oral corticosteroids for adults during exacerbation of asthma -
(ANSWER)40-60 mg/day
either as a single dose of divided BID
Duration of treatment of oral corticosteroids for asthma exacerbation -
(ANSWER)3-10 days or until symptoms resolve
(no evidence that tapering dose of PO steroids prevents relapse)
When treating exacerbation of asthma, what is the preferred treatment plan? -
(ANSWER)Alternate days rather than daily treatment.
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What additional medications are required to be given concurrent with systemic
corticosteroids to prevent corticosteroid induced bone mineral loss? -
(ANSWER)Vitamin D and Calcium
Should systemic corticosteroids be rapidly discontinued? - (ANSWER)No, to
prevent adrenal insufficiency
Name some mediator inhibitors to treat asthma - (ANSWER)Cromolyn sodium
and nedocromil
What is the mechanism of action of mediator inhibitors? - (ANSWER)prevent
asthma symptoms, improve airway function in pt w/mild persistent of exercise
induce asthma
When are mediator inhibitors effective? - (ANSWER)Before allergen exposure or
exercise
Do not relieve asthmatic symptoms once present.
Name the Long acting beta 2 agonist (LABA) for asthma - (ANSWER)Salmeterol
and Formoteol
How are LABA's delivered? - (ANSWER)dry powder
What are LABA's used for - (ANSWER)Long term prevention of asthma symptoms