Conceptual Actual Emended Exam Questions
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1. What is the process by which RNA directs the synthesis of polypeptides? -
ANSWER Translation -
Translation refers to this process. Transcription is another process in which RNA is
synthesized. Mutation means genetic material has been modified through
inheritance. Creation is a term that does not apply in this context.
2. Which of the following is not a cellular function? - ANSWER Combustion -
All living cells must absorb and metabolize sources of energy, excrete waste and
by-products of those processes, and reproduce to continue offspring. Pyrotechnic
processes (i.e. combustion) are generally metaphorical.
3. What are mitochondria responsible for? - ANSWER Energy production -
Mitochondria are the energy production organelles of the cell responsible for the
major metabolic processes of creating units of energy (e.g., ATP).
4. What is the recurrence rate for autosomal dominant disease? - ANSWER
50% -
For a couple in which one or both partners are affected by the disease, the chance
of each child being heterozygous affected is 50%.
,5. Which of the following statements is true about autosomal recessive disease?
- ANSWER It affects both men and women equally -
A criterion for recognizing the inheritance of an autosomal recessive disease is
that men and women will be affected by it in equal measure.
6. What is the proportion of the population affected by a disease at the specific
point in time? - ANSWER Prevalence rate -
Incidence rate refers to how many new cases there are of a disease within a
period of time divided by the number of the population's individuals. The
prevalence rate is affected by the incidence rate and how long the affected
patients survive. Risk factor is anything that could lead to disease. Relative risk is
the measure of a risk factor effect.
7. Which of the following should be completed when a disease is multifactorial
but has a larger genetic component? - ANSWER Get a thorough family
history -
Environment and lifestyle choices may influence a disease, but diseases such as
breast cancer are hereditary, so the family history should be reviewed.
8. Which action is the purpose of the inflammatory process? - ANSWER To
destroy foreign, invasive microorganisms -
The general purpose of inflammation is to initiate the destruction of foreign or
invasive organisms. As a secondary effect, it increases the healing and immune
response processes of the body.
,9. What causes edema that occurs during the inflammatory process? - ANSWER
Increased vascular permeability -
Increased pressure in the vasculature secondary to the vasodilatory effects of
inflammation will result in the leakage of fluid into third spaces (i.e., edema).
10. In what structure do B lymphocytes mature and become B cells? - ANSWER
Bone marrow -
The bone marrow is where immature immune cells, such as B and T lymphocytes,
reside to mature into B cells. After this maturation process, these cells migrate to
other organ sites such as the thyroid, spleen, and thymus to enter their final
stages of differentiation and development.
11. Which type of immunity occurs when antibodies are transferred from donor
to recipient? - ANSWER Passive acquired immunity -
Active immune processes are the self-originating processes of the immune system
that occur from (acquired) or without (innate) prior exogenous simulation or
exposure to foreign antigens. Passive immunity is stabilized. Existing immune
responses that are present with or without simulation can arise or be created
from oneself (innate) or acquired from an outside source (e.g. donor antibodies).
12. What does T-cell activity cause in older adults? - ANSWER Increased
susceptibility for infection -
As the human body ages, the immune system's effectiveness to coordinate
responses to pathogens and other foreign antigens wanes and the risk for disease
increases.
, 13. What is a dermatitis caused by prolonged exposure to chemicals such as acids
or soaps also known as? - ANSWER Irritant contact dermatitis -
Prolonged, superficial skin exposure to foreign irritants (e.g., acids or soaps) is a
manifestation of an innate, local inflammatory response. The conditions of
allergic, stasis, and atopic dermatitis involve more systemic processes of the
immune system and vasculature.
14. Which of the following is a self-limiting disease associated with Herpes type
viruses and a herald patch? - ANSWER Pityriasis rosea -
Lichen planus, acne vulgaris, and erythema multiforme are conditions generally
associated with or caused by autoimmune dysregulation, bacteria, and varieties of
foreign antigen (medications, virus, etc.). Pityriasis rosea in particular is associated
with and triggered by Herpes viruses, manifesting itself as a herald patch.
15. What is a furuncle? - ANSWER An infection of the hair follicle that extends
to the surrounding tissue -
Abscess, dermis, and fungal infections are generally more widespread or larger
processes that require broad or systemic treatment. A furuncle, though
uncomfortable to painful, is a generally localized infection that is self-resolving or
that requires local, minor treatment.
What type of lesion may be malignant in the form of squamous cell carcinoma
(SCC)? - ANSWER Actinic keratosis -
Actinic keratosis, which is caused by exposure to UV radiation, is a precursor lesion
of SCC