AANP EXAM 2025 (ACTUAL EXAM)
QUESTIONS AND VERIFIED
ANSWERS
A 65-year-old woman presents for a follow-up examination after a new
patient visit. She has not seen a healthcare provider for several years. She
is a smoker and her hypertension is now adequately controlled with
medication. Her mother died at age 40 from a heart attack. The fasting lipid
profile shows cholesterol = 240 mg/dL, HDL = 30, and LDL = 200. In
addition to starting Therapeutic Lifestyle Changes, the nurse practitioner
should start the patient on:
1.bile acid sequestrant.
2. a statin drug.
3. a cholesterol absorption inhibitor.
4. low-dose aspirin....ANSWER...A statin drug
The most commonly prescribed medication for mild systemic lupus
erythematosus (SLE) is:
1. azathioprine (AZA).
2. belimumab (Benlysta).
3. ibuprofen (Advil).
4. cyclophosphamide (Cytoxan)....ANSWER...ibuprofen (advil)
The most common sign of cervical cancer is:
1. postcoital bleeding.
2. strong odor from vaginal discharge.
3. itching in the vaginal area.
4. molluscum contagiosum....ANSWER...postcoital bleeding
The nurse practitioner prescribes amitriptyline (Elavil) for a patient with
neuropathic pain secondary to diabetes mellitus. On follow-up, the patient
complains of urine retention and dry mouth. The practitioner would:
1. discontinue amitriptyline and begin ibuprofen (Motrin).
2. refer to physical therapy.
3. start methocarbamol (Robaxin).
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,4. discontinue amitriptyline and begin gabapentin
(Neurontin)....ANSWER...discontinue amitriptyline and begin gabapentin
(neurontin)
A 17-year-old male with rheumatoid arthritis is being treated with an NSAID
and omeprazole (Prilosec). The patient complains of headache, abdominal
pain, and gas. These symptoms are most likely:
1. associated with the omeprazole.
2. related to the underlying condition.
3. the result of the NSAID.
4. caused by viral gastroenteritis....ANSWER...associated with the
omeprazole
The medication of choice for the initial treatment of juvenile rheumatoid
arthritis is:
1. acetaminophen.
2. prednisone.
3. aspirin.
4. ibuprofen....ANSWER...ibuprofen
A 12-year-old with sickle cell anemia has recently experienced a sickle cell
crisis and presents for a follow-up examination after a recent
hospitalization. It is most important to continue monitoring growth,
development, and:
1. white blood cell levels.
2. fecal occult blood test.
3. hemoglobin levels.
4. urine dipsticks....ANSWER...hemoglobin levels
A 90-year-old female is brought to the clinic by her neighbor. She states
that everything is fine, but the nurse practitioner notes that she has poor
hygiene and bruises on her trunk. The neighbor is concerned that the
patient often has no money to buy food, despite income from social security
and a coal miner's pension. The nurse practitioner suspects abuse. Which
of the following is the nurse practitioner obligated to do next?
1. Report the case to the proper authorities.
2. Tell the neighbor to check on the woman daily and report back.
3. Document the data and report the information to risk management.
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, 4. Call the patient's family and inquire about the
concerns....ANSWER...report the case to proper authorities
In most cases, the first manifestation of Alzheimer's disease is:
1. impaired judgment.
2. decrease in short-term memory.
3. disorientation in time and place.
4. decrease in long-term memory....ANSWER...decrease in short-term
memory
The optimal treatment for latent tuberculosis is:
1. rifampin (Rifadin) for 5 months.
2. isoniazid (Nydrazid) for 9 months.
3. pyrazinamide for 6 months.
4. ethambutol for 6 months....ANSWER...osioniazid (nydrazid) for 9 months
Unilateral spontaneous serous or serosanguineous discharge from a single
duct of a breast is most often caused by:
1. intraductal papilloma.
2. mucinous breast lesions.
3. Paget's disease.
4. ductal carcinoma in situ....ANSWER...intraductal papilloma
A young child with asthma presents for follow-up evaluation. After
numerous changes in medications and doses, the parents report that the
child continues to have difficulty with coughing, especially during the night.
Which of the following conditions would be the most likely cause of the
continued asthma symptoms?
1. Vocal cord dysfunction
2. Cystic fibrosis
3. Gastroesophageal reflux
4. Allergic rhinitis...ANSWER...gastroesophageal reflux
A pregnant woman with known HIV infection can reduce the risk of
perinatal transmission through zidovudine (Retrovir) therapy. Based on
current research, optimal therapy is to start daily dosing:
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QUESTIONS AND VERIFIED
ANSWERS
A 65-year-old woman presents for a follow-up examination after a new
patient visit. She has not seen a healthcare provider for several years. She
is a smoker and her hypertension is now adequately controlled with
medication. Her mother died at age 40 from a heart attack. The fasting lipid
profile shows cholesterol = 240 mg/dL, HDL = 30, and LDL = 200. In
addition to starting Therapeutic Lifestyle Changes, the nurse practitioner
should start the patient on:
1.bile acid sequestrant.
2. a statin drug.
3. a cholesterol absorption inhibitor.
4. low-dose aspirin....ANSWER...A statin drug
The most commonly prescribed medication for mild systemic lupus
erythematosus (SLE) is:
1. azathioprine (AZA).
2. belimumab (Benlysta).
3. ibuprofen (Advil).
4. cyclophosphamide (Cytoxan)....ANSWER...ibuprofen (advil)
The most common sign of cervical cancer is:
1. postcoital bleeding.
2. strong odor from vaginal discharge.
3. itching in the vaginal area.
4. molluscum contagiosum....ANSWER...postcoital bleeding
The nurse practitioner prescribes amitriptyline (Elavil) for a patient with
neuropathic pain secondary to diabetes mellitus. On follow-up, the patient
complains of urine retention and dry mouth. The practitioner would:
1. discontinue amitriptyline and begin ibuprofen (Motrin).
2. refer to physical therapy.
3. start methocarbamol (Robaxin).
1|Page
,4. discontinue amitriptyline and begin gabapentin
(Neurontin)....ANSWER...discontinue amitriptyline and begin gabapentin
(neurontin)
A 17-year-old male with rheumatoid arthritis is being treated with an NSAID
and omeprazole (Prilosec). The patient complains of headache, abdominal
pain, and gas. These symptoms are most likely:
1. associated with the omeprazole.
2. related to the underlying condition.
3. the result of the NSAID.
4. caused by viral gastroenteritis....ANSWER...associated with the
omeprazole
The medication of choice for the initial treatment of juvenile rheumatoid
arthritis is:
1. acetaminophen.
2. prednisone.
3. aspirin.
4. ibuprofen....ANSWER...ibuprofen
A 12-year-old with sickle cell anemia has recently experienced a sickle cell
crisis and presents for a follow-up examination after a recent
hospitalization. It is most important to continue monitoring growth,
development, and:
1. white blood cell levels.
2. fecal occult blood test.
3. hemoglobin levels.
4. urine dipsticks....ANSWER...hemoglobin levels
A 90-year-old female is brought to the clinic by her neighbor. She states
that everything is fine, but the nurse practitioner notes that she has poor
hygiene and bruises on her trunk. The neighbor is concerned that the
patient often has no money to buy food, despite income from social security
and a coal miner's pension. The nurse practitioner suspects abuse. Which
of the following is the nurse practitioner obligated to do next?
1. Report the case to the proper authorities.
2. Tell the neighbor to check on the woman daily and report back.
3. Document the data and report the information to risk management.
2|Page
, 4. Call the patient's family and inquire about the
concerns....ANSWER...report the case to proper authorities
In most cases, the first manifestation of Alzheimer's disease is:
1. impaired judgment.
2. decrease in short-term memory.
3. disorientation in time and place.
4. decrease in long-term memory....ANSWER...decrease in short-term
memory
The optimal treatment for latent tuberculosis is:
1. rifampin (Rifadin) for 5 months.
2. isoniazid (Nydrazid) for 9 months.
3. pyrazinamide for 6 months.
4. ethambutol for 6 months....ANSWER...osioniazid (nydrazid) for 9 months
Unilateral spontaneous serous or serosanguineous discharge from a single
duct of a breast is most often caused by:
1. intraductal papilloma.
2. mucinous breast lesions.
3. Paget's disease.
4. ductal carcinoma in situ....ANSWER...intraductal papilloma
A young child with asthma presents for follow-up evaluation. After
numerous changes in medications and doses, the parents report that the
child continues to have difficulty with coughing, especially during the night.
Which of the following conditions would be the most likely cause of the
continued asthma symptoms?
1. Vocal cord dysfunction
2. Cystic fibrosis
3. Gastroesophageal reflux
4. Allergic rhinitis...ANSWER...gastroesophageal reflux
A pregnant woman with known HIV infection can reduce the risk of
perinatal transmission through zidovudine (Retrovir) therapy. Based on
current research, optimal therapy is to start daily dosing:
3|Page
