Choice and Conceptual Actual Emended Exam
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1. A patient is diagnosed with color blindness. Which inheritance pattern explains this
condition?
A. Autosomal dominant
B. Autosomal recessive
C. X-linked recessive
D. Mitochondrial inheritance
2. Hemophilia follows which pattern of inheritance?
A. Autosomal dominant
B. X-linked recessive
C. Autosomal recessive
D. Y-linked
3. Which is an example of an autosomal dominant disorder?
A. Huntington’s disease
B. Tay-Sachs disease
C. Cystic fibrosis
D. Phenylketonuria
4. Which condition is classified as an autosomal recessive disorder?
A. Achondroplasia
B. Sickle cell anemia
C. Huntington’s disease
D. Neurofibromatosis
,5. Thiazide diuretics (e.g., chlorothiazide) reduce blood pressure by which mechanism?
A. Inhibiting sodium reabsorption in the distal tubule
B. Blocking aldosterone receptors
C. Dilating coronary arteries
D. Inhibiting calcium entry into vascular smooth muscle
6. Which is a first-line thiazide diuretic for hypertension?
A. Furosemide
B. Chlorothiazide (Diuril)
C. Spironolactone
D. Hydrochloride
7. Calcium channel blockers (CCBs) lower blood pressure by:
A. Increasing sodium reabsorption
B. Slowing calcium entry into cardiac and vascular smooth muscle
C. Stimulating beta-adrenergic receptors
D. Blocking angiotensin II
8. Which adverse effect is MOST concerning with ACE inhibitors?
A. Bradycardia
B. Hyperkalemia
C. Hypocalcemia
D. Hypoglycemia
9. Which drug class works by blocking the effects of norepinephrine at beta receptors, thereby
lowering heart rate?
A. Beta blockers
B. ACE inhibitors
C. Calcium channel blockers
D. Loop diuretics
10. A patient has an ejection fraction of 40%. This finding indicates:
A. Normal cardiac output
,B. Reduced ventricular contractility
C. Increased preload
D. Excessive afterload
11. The anterior pituitary gland produces which of the following hormones?
A. ADH and oxytocin
B. Epinephrine and norepinephrine
C. FSH, LH, ACTH, TSH, prolactin, growth hormone
D. Insulin and glucagon
12. The adrenal glands secrete:
A. Cortisol, epinephrine, norepinephrine
B. ADH and oxytocin
C. Growth hormone and prolactin
D. Thyroxine and calcitonin
13. Which drug is used to treat non-small cell lung cancer with an EGFR mutation?
A. Imatinib
B. Tagrisso (osimertinib)
C. Tamoxifen
D. Rituximab
14. Escitalopram (Lexapro) belongs to which drug class?
A. SNRI
B. MAOI
C. SSRI
D. TCA
15. Sickle cell crisis first-line management includes:
A. Blood transfusion
B. IV isotonic fluids
C. Broad-spectrum antibiotics
D. Anticoagulation therapy
, coronary artery disease (CAD) - ANSWER a condition affecting arteries of the heart that
reduces the flow of blood and the delivery of oxygen and nutrients to the myocardium; most
often caused by atherosclerosis
Glucocorticoids (cortisol) - ANSWER Adrenal cortex
stimulates gluconeogenesis
anti-inflammatory
immunosuppression
chemotherapeutic agents - ANSWER synthetic chemicals used to interfere with the
functioning of foreign cell populations; this term is frequently used to refer to the drug therapy
of neoplasms, but it also refers to drug therapy affecting any foreign cell
chemotherapeutic index - ANSWER maximum tolerable dose per kilogram of body weight,
divided by the minimum dose per kilogram of body weight, that will cure the disease
breast cancer treatment - ANSWER Trust HER!
{Trastuzumab is used to treat Breast Cancers with HER2/neu receptors.
This drug is a monoclonal antibody specific for HER2/neu receptor }
Topoisomerase inhibitors - ANSWER interfere with the action of topoisomerase enzymes
(topoisomerase I and II). During the process of chemo treatments, topoisomerase enzymes
control the manipulation of the structure of DNA necessary for replication.
Methotrexate (Rheumatrex) - ANSWER rheumatoid arthritis
Folic acid antagonist