Chemistry in Medicine Cisplatin → see organic
Salicylic Acid
cells that are no longer needed , undergo programmed cen death * White crystalline solid
Digestion
* in adult tissues cell death division * group on benzene ring phenol OH group
Remedies
cell OH →
'
-
-
-
. .
-
=
,
* cancer : cells don't die + divide in unregulated way / abnormal growth Acidic
A Indigestion caused by excess stomach acid / Hat tissue tumour 'i acidic enough to react w/ NaOH but
of new = not NAHH, or
* Treated by consuming indigestion remedies that contain bases
* when cisplatin enters nucleus ,
binds + forms complex w/ guanine Narco ,
When the bases reach stomach , can neutralise some HCl
↳ in
ligand Ñ
* amount of
ii
stomach stomach acid to normal levels it form bond w/ another guanine either ONA
, can a on same DNA strand or OH
+ NaOH →
1-21-110
across helix → results in
'
kink
'
in DNA strands .
: DNA replication OH ON a
fact ,
+ IHCI → lack + thot CO2 $ fact, is insoluble and Mythili is
impossible Ican 1- uncoil
'
1- Sep . .
: dies ) disodium salicylate
sparingly back titration 211 's
soluble
* Before binding lost t bonds form w/ Non guanine
: .
are
Ñ
,
Mglotll ,
+ IHCI →
Mgch + 11h0 A base is reacted wl excess HCl I 103
Neff Nat 1-1-1
-
0
OH 1- g
* remaining HCl titrated against NaOH RISKS :
Nd " "
OH
°"
WI phenolphthalein * toxic side effects e.g. kidney damage ,
weakened immune monosodium salicylate
←
system + hair loss '
↳ '
soluble aspirin more quickly absorbed by digesti
gµ in pH
→
↳ in general anticancer drugs damage normal cells as well
system faster pain relief
.
.
.
* .
: try to chemically alter drugs so oniu active near
* Outer layer of skin is covered by oily layer llontains fatty acids secreted by glands
Preventing
cells
immiscible in waver .
cancerous
Blood
"
4> Acid mantle :
pH of around 5.5 * la important in blood C
* Sweat contains lactic acid + a. a's which can affect pH of skin Aspirin * if edta added to blood , for
Acid " " -
mantle is :
* used to relieve mild to moderate pain + reduce inflammation (a ma ,
+ edta can
* effective barrier to bacteria viruses due to acidic
⑨
+ nature
4> side effects : stomach Ulcers ,
alt .
pain relief available
A waterproof la " still present in blood but
* active ingredient acetyl salicylic acid lethanoate
: ester 01
* lubricates the skin reaction favoured by entropy
salicylic acid
* Blood is alkaline .
'
.
if acid adapted bacteria is successful in penetrating acid mantle
,
be less & blood banks depend on s
well adapted to alkaline blood
Preparation :
.
Factor's affecting pH
* reflux 1- hydroxy benzoic acid
ethanoic anhydride in presence of
ltalicylicacidlt
few drops of
Identifying
A soap is Na Ork salt 01 tailor molecule TLC :
long chain fatty acid → allows non polar
1-1,1704 Water added cooled bath
-
+ in ice
* Verity identity d
if 01
.
to remove oil , whilst polar head allows H bonds w/
É
water
* too frequent cleaning of Shin , esp wl alkaline soap ,
will remove fatty acids from mantle
% É 11° OH
+
*
°" ° Ho en
+ ,
↳ can leave skin dry + open to infection from bacteria + viruses Hsc 0 CH , o A dissolve lab made
OH lthd " " " id
↳ structure or acid mantle can be restored using mildly acid cleaners w/ fatty acids A place TLC plate i
yµ ,
gamey , , acid, ethan, ,, annydr;D , 1- lover with a l
d
Salicylic Acid
cells that are no longer needed , undergo programmed cen death * White crystalline solid
Digestion
* in adult tissues cell death division * group on benzene ring phenol OH group
Remedies
cell OH →
'
-
-
-
. .
-
=
,
* cancer : cells don't die + divide in unregulated way / abnormal growth Acidic
A Indigestion caused by excess stomach acid / Hat tissue tumour 'i acidic enough to react w/ NaOH but
of new = not NAHH, or
* Treated by consuming indigestion remedies that contain bases
* when cisplatin enters nucleus ,
binds + forms complex w/ guanine Narco ,
When the bases reach stomach , can neutralise some HCl
↳ in
ligand Ñ
* amount of
ii
stomach stomach acid to normal levels it form bond w/ another guanine either ONA
, can a on same DNA strand or OH
+ NaOH →
1-21-110
across helix → results in
'
kink
'
in DNA strands .
: DNA replication OH ON a
fact ,
+ IHCI → lack + thot CO2 $ fact, is insoluble and Mythili is
impossible Ican 1- uncoil
'
1- Sep . .
: dies ) disodium salicylate
sparingly back titration 211 's
soluble
* Before binding lost t bonds form w/ Non guanine
: .
are
Ñ
,
Mglotll ,
+ IHCI →
Mgch + 11h0 A base is reacted wl excess HCl I 103
Neff Nat 1-1-1
-
0
OH 1- g
* remaining HCl titrated against NaOH RISKS :
Nd " "
OH
°"
WI phenolphthalein * toxic side effects e.g. kidney damage ,
weakened immune monosodium salicylate
←
system + hair loss '
↳ '
soluble aspirin more quickly absorbed by digesti
gµ in pH
→
↳ in general anticancer drugs damage normal cells as well
system faster pain relief
.
.
.
* .
: try to chemically alter drugs so oniu active near
* Outer layer of skin is covered by oily layer llontains fatty acids secreted by glands
Preventing
cells
immiscible in waver .
cancerous
Blood
"
4> Acid mantle :
pH of around 5.5 * la important in blood C
* Sweat contains lactic acid + a. a's which can affect pH of skin Aspirin * if edta added to blood , for
Acid " " -
mantle is :
* used to relieve mild to moderate pain + reduce inflammation (a ma ,
+ edta can
* effective barrier to bacteria viruses due to acidic
⑨
+ nature
4> side effects : stomach Ulcers ,
alt .
pain relief available
A waterproof la " still present in blood but
* active ingredient acetyl salicylic acid lethanoate
: ester 01
* lubricates the skin reaction favoured by entropy
salicylic acid
* Blood is alkaline .
'
.
if acid adapted bacteria is successful in penetrating acid mantle
,
be less & blood banks depend on s
well adapted to alkaline blood
Preparation :
.
Factor's affecting pH
* reflux 1- hydroxy benzoic acid
ethanoic anhydride in presence of
ltalicylicacidlt
few drops of
Identifying
A soap is Na Ork salt 01 tailor molecule TLC :
long chain fatty acid → allows non polar
1-1,1704 Water added cooled bath
-
+ in ice
* Verity identity d
if 01
.
to remove oil , whilst polar head allows H bonds w/
É
water
* too frequent cleaning of Shin , esp wl alkaline soap ,
will remove fatty acids from mantle
% É 11° OH
+
*
°" ° Ho en
+ ,
↳ can leave skin dry + open to infection from bacteria + viruses Hsc 0 CH , o A dissolve lab made
OH lthd " " " id
↳ structure or acid mantle can be restored using mildly acid cleaners w/ fatty acids A place TLC plate i
yµ ,
gamey , , acid, ethan, ,, annydr;D , 1- lover with a l
d
