1. True/False: Blood tests for tumor markers are the single best
screening tool for cancer.
2. Tissue biopsy is of critical importance in what role?
3. Show Answers:
a. List two signs or symptoms a patient may present with
that might indicate a cancer diagnosis:
b. What are two side effects commonly experienced by cancer
patients?
4. Explain the TNM system: (10 points)
5. Short answers:
a. When would surgery be appropriate in the treatment of cancer?
b. Most chemotherapeutic drugs cause pancytopenia due to bone
marrow suppression. What are the 3 possible adverse outcomes
of this?
6. True/False: Cell proliferation is the process in which proliferating
cells become more specialized cell types.
7. True/False: Cell differentiation is the process of increasing cell
numbers by mitotic cell division.
8. What are two important properties that stem cells possess?
9. Which of the following are most likely to have arisen from an adult
stem cell?
a. Muscle
b. Bone
c. Epithelial
d. Neural
10. What is angiogenesis? Why do tumors need it?
11. What are normal genes called that become cancer causing if
mutated?
12. What is a tumor suppressor gene? Give one example.
, 13. Determine if the tumor is benign or malignant based on the
nomenclature:
a. Papilloma
b. Lipoma
c. Leiomyosarcoma
d. Hemangioma
e. Adenocarcinoma
f. Neuroblastoma
g. Adenoma
h. Melanoma
i. Lymphoma
j. Glioma
14. A 62-year-old man with a 30-pack year smoking history is diagnosed
with small cell lung cancer with metastasis to the bone. (1) Explain
the process of how cancer spreads metastatically. (2) What
symptoms might he have presented with? (3) Which screening test
would he have benefited from?
15. Benign tumors have which of the following characteristics?
Select all that apply.
a. Undifferentiated cells
b. Grows by expansion
c. Gains access to blood and lymph channels
d. Growth may stop or regress
16. What are the genetic events that can lead to cancer? Select all that
apply.
a. Gene amplification
b. Pleomorphism
c. Point mutation
d. Seeding
screening tool for cancer.
2. Tissue biopsy is of critical importance in what role?
3. Show Answers:
a. List two signs or symptoms a patient may present with
that might indicate a cancer diagnosis:
b. What are two side effects commonly experienced by cancer
patients?
4. Explain the TNM system: (10 points)
5. Short answers:
a. When would surgery be appropriate in the treatment of cancer?
b. Most chemotherapeutic drugs cause pancytopenia due to bone
marrow suppression. What are the 3 possible adverse outcomes
of this?
6. True/False: Cell proliferation is the process in which proliferating
cells become more specialized cell types.
7. True/False: Cell differentiation is the process of increasing cell
numbers by mitotic cell division.
8. What are two important properties that stem cells possess?
9. Which of the following are most likely to have arisen from an adult
stem cell?
a. Muscle
b. Bone
c. Epithelial
d. Neural
10. What is angiogenesis? Why do tumors need it?
11. What are normal genes called that become cancer causing if
mutated?
12. What is a tumor suppressor gene? Give one example.
, 13. Determine if the tumor is benign or malignant based on the
nomenclature:
a. Papilloma
b. Lipoma
c. Leiomyosarcoma
d. Hemangioma
e. Adenocarcinoma
f. Neuroblastoma
g. Adenoma
h. Melanoma
i. Lymphoma
j. Glioma
14. A 62-year-old man with a 30-pack year smoking history is diagnosed
with small cell lung cancer with metastasis to the bone. (1) Explain
the process of how cancer spreads metastatically. (2) What
symptoms might he have presented with? (3) Which screening test
would he have benefited from?
15. Benign tumors have which of the following characteristics?
Select all that apply.
a. Undifferentiated cells
b. Grows by expansion
c. Gains access to blood and lymph channels
d. Growth may stop or regress
16. What are the genetic events that can lead to cancer? Select all that
apply.
a. Gene amplification
b. Pleomorphism
c. Point mutation
d. Seeding
