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NURS 231 Pathophysiology Module 1 Exam and Explanation FALL 2025 (Portage learning)

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1. A bodybuilder's muscles will display hyperplasia. Answer: False Explanation:  Bodybuilders experience hypertrophy (increase in muscle fiber size), not hyperplasia (increase in cell number). **Arnold received a huge trophy for getting huge hypertrophy muscles**  Hyperplasia occurs in tissues with high cell turnover (e.g., uterine lining during pregnancy, wound healing). Memory Tip: “Hyper = more cells, Hypertrophy = bigger cells.” 2. Barrett esophagus is an example of dysplasia. Answer: False Explanation:  Barrett esophagus is metaplasia — replacement of squamous epithelium with columnar epithelium due to chronic acid reflux.  Dysplasia = abnormal, disordered cell growth, often precancerous (e.g., cervical dysplasia). Barrett esophagus is a precancerous condition where chronic GERD damages the normal stratified squamous epithelium of the lower esophagus. The body adapts by replacing it with columnar epithelium containing goblet cells (like the intestine, mucus-secreting cells), a process

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Institution
NURS 231
Course
NURS 231

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1. A bodybuilder's muscles will display hyperplasia.

Answer: False

Explanation:

• Bodybuilders experience hypertrophy (increase in muscle fiber
size), not hyperplasia (increase in cell number). **Arnold received
a huge trophy for getting huge hypertrophy muscles**

• Hyperplasia occurs in tissues with high cell turnover (e.g., uterine
lining during pregnancy, wound healing).
💡 Memory Tip: “Hyper = more cells, Hypertrophy = bigger cells.”


2. Barrett esophagus is an example of dysplasia.

Answer: False

Explanation:

• Barrett esophagus is metaplasia — replacement of squamous
epithelium with columnar epithelium due to chronic acid reflux.

• Dysplasia = abnormal, disordered cell growth, often precancerous
(e.g., cervical dysplasia).



Barrett esophagus is a precancerous condition where chronic GERD
damages the normal stratified squamous epithelium of the lower
esophagus. The body adapts by replacing it with columnar epithelium
containing goblet cells (like the intestine, mucus-secreting cells), a process
called intestinal metaplasia. This new lining resists acid better but
increases cancer risk.

💡 Memory tip: “Barrett builds barriers” — the esophagus builds a new
lining (columnar) to “protect” from acid, but it comes at a cancer risk.



3. Hypertrophy is an increase in the size of an organ or tissue caused
by an increase in the number of cells.

Answer: False

Explanation:

, • Hypertrophy = increase in cell size, not cell number.

• Increase in cell number = hyperplasia.



4. Hypertrophy can occur under normal and pathological conditions.

Answer: True

Examples:

• Normal: Exercise → skeletal muscle enlargement.

• Pathological: Hypertension → left ventricular hypertrophy.



5. Match the following:

Definition Correct
Term

Deals with the cause of death in a population Mortality

Number of new cases in a population at risk Incidence
during a specified time

Number of people with the disease in a population Prevalenc
at a given time e

Effect of illness on one’s life Morbidity



💡 Memory Tip: I = new cases (Incidence), P = present cases
(Prevalence).


6. Which is NOT true of the cytoskeleton?

Answer: “It includes peroxisomes and proteasomes” is NOT true.

Explanation:

• The cytoskeleton is made of microtubules, microfilaments,
intermediate filaments.

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Institution
NURS 231
Course
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