Midterm Exam: NR565/ NR 565 Advanced
Pharmacology Care Exam | Questions With Verified
Answers
ASCVD Risk Score - ANSWER: Used in children aged 9-11 and 19-21, and adults
every 5 years after 20, with greater risk for those with diabetes and a risk score >7.5%
Ezetimibe Use - ANSWER: Can be used in pregnancy/breastfeeding, as
monotherapy or adjunct therapy with a statin or fibrate
Ezetimibe - ANSWER: Cholesterol Absorption Inhibitor that lowers cholesterol levels
by decreasing absorption from the small intestine, without affecting triglycerides
Lifestyle Changes for High Cholesterol - ANSWER: Non-drug measures to lower LDL,
including diet, exercise, weight control, and smoking cessation
Minimizing Side Effects - ANSWER: Non-statins like fibrates, ezetimibe, bile acid
sequestrants, or statins for generally well-tolerated side effects
Organic Nitrates Therapeutic Action - ANSWER: Direct relaxant effect on vascular
smooth muscles, dilation of coronary vessels, reduction of preload and afterload, and
promotion of vasodilation
Ranolazine Contraindications - ANSWER: Inhibited by CYP3A4 inhibitors, increasing
the risk of torsades de pointes, including grapefruit juice, HIV protease inhibitors,
macrolide antibiotics, azole antifungal drugs, and some CCB
Statin Prescription Age - ANSWER: Avoid in children under 10
CCB Role in Variant Angina - ANSWER: Promotes relaxation of coronary artery
spasm, increasing cardiac oxygen supply #$%^&*(*
&^%$%^&
HF Worsening Symptoms Medication - ANSWER: Aldosterone antagonist that
*(*&^%$%
promotes myocardial remodeling and fibrosis to help with symptoms
^&*(*&^%
CCB Stable Angina - ANSWER: Promotes relaxation of peripheral arterioles, $#$%^&*
decreasing afterload and reducing cardiac oxygen demand &^%$#$%
^&*(*&^%
Nitro Patches Side Effect Response - ANSWER: Prescribe a BB to help with $#$%^&*
increased heart rate
)(*&^%$#
CYP450 Inhibitors and Reducers - ANSWER: When not used correctly, they lead to %^&*()*&
increased side effects, adverse reactions, and toxicity ^%$%^&*
)(*&^%$%
^&*(*&^%
$%^&*(*&
^%$
, Midterm Exam: NR565/ NR 565 Advanced
Pharmacology Care Exam | Questions With Verified
Answers
Gouty Arthritis Treatment Decision - ANSWER: In patients with infrequent flareups
(less than three per year), NSAIDs are the first line agent for relieving pain
Gouty Arthritis NSAID Ineffectiveness - ANSWER: Prescribe a glucocorticoid
(prednisone) or make dietary changes
Colchicine Long Term Treatment - ANSWER: Considered for long term treatment if a
person has three or more gouty attacks per year
Colchicine Contraindications - ANSWER: Should not be taken with statins or CYP3A4
inhibitors
Colchicine Adverse Effects - ANSWER: Nausea, vomiting, diarrhea,
myelosuppression, myopathy, and rhabdomyolysis
Allopurinol Long Term Effect - ANSWER: Can lead to severe cutaneous adverse
reaction (SCAR) with symptoms like rash, fever, eosinophilia, and liver and kidney
function issues
Febuxostat Co-Administration - ANSWER: Should be co-administered with NSAIDs
or colchicine
Untreated Gout Complications - ANSWER: Erosion and irreversible joint damage,
renal damage, and tophi formation
Alendronate Patient Education - ANSWER: Minimize risk of esophagitis by
swallowing the pill whole with a full glass of water, then sitting up for at least 30 min, #$%^&*(*
and taking the med 30 min prior to other intake &^%$%^&
*(*&^%$%
Ibandronate Dietary Supplement Interference - ANSWER: Interferes with calcium,
magnesium, and iron absorption ^&*(*&^%
$#$%^&*
Osteoporosis 1st Line Treatment - ANSWER: Alendronate is the first line treatment &^%$#$%
^&*(*&^%
Allopurinol Safety in Renal Dysfunction - ANSWER: Safe to use in patients with renal $#$%^&*
dysfunction or who over produce uric acid
)(*&^%$#
DMARDs Baseline Diagnostics - ANSWER: Includes CBC with WBC differential, s/s %^&*()*&
of infection, malignancies, pregnancy rule out, ALT, AST, serum creatinine, ^%$%^&*
comprehensive history and physical exam, and assessment of immunocompetence and )(*&^%$%
liver and renal status ^&*(*&^%
$%^&*(*&
^%$
Pharmacology Care Exam | Questions With Verified
Answers
ASCVD Risk Score - ANSWER: Used in children aged 9-11 and 19-21, and adults
every 5 years after 20, with greater risk for those with diabetes and a risk score >7.5%
Ezetimibe Use - ANSWER: Can be used in pregnancy/breastfeeding, as
monotherapy or adjunct therapy with a statin or fibrate
Ezetimibe - ANSWER: Cholesterol Absorption Inhibitor that lowers cholesterol levels
by decreasing absorption from the small intestine, without affecting triglycerides
Lifestyle Changes for High Cholesterol - ANSWER: Non-drug measures to lower LDL,
including diet, exercise, weight control, and smoking cessation
Minimizing Side Effects - ANSWER: Non-statins like fibrates, ezetimibe, bile acid
sequestrants, or statins for generally well-tolerated side effects
Organic Nitrates Therapeutic Action - ANSWER: Direct relaxant effect on vascular
smooth muscles, dilation of coronary vessels, reduction of preload and afterload, and
promotion of vasodilation
Ranolazine Contraindications - ANSWER: Inhibited by CYP3A4 inhibitors, increasing
the risk of torsades de pointes, including grapefruit juice, HIV protease inhibitors,
macrolide antibiotics, azole antifungal drugs, and some CCB
Statin Prescription Age - ANSWER: Avoid in children under 10
CCB Role in Variant Angina - ANSWER: Promotes relaxation of coronary artery
spasm, increasing cardiac oxygen supply #$%^&*(*
&^%$%^&
HF Worsening Symptoms Medication - ANSWER: Aldosterone antagonist that
*(*&^%$%
promotes myocardial remodeling and fibrosis to help with symptoms
^&*(*&^%
CCB Stable Angina - ANSWER: Promotes relaxation of peripheral arterioles, $#$%^&*
decreasing afterload and reducing cardiac oxygen demand &^%$#$%
^&*(*&^%
Nitro Patches Side Effect Response - ANSWER: Prescribe a BB to help with $#$%^&*
increased heart rate
)(*&^%$#
CYP450 Inhibitors and Reducers - ANSWER: When not used correctly, they lead to %^&*()*&
increased side effects, adverse reactions, and toxicity ^%$%^&*
)(*&^%$%
^&*(*&^%
$%^&*(*&
^%$
, Midterm Exam: NR565/ NR 565 Advanced
Pharmacology Care Exam | Questions With Verified
Answers
Gouty Arthritis Treatment Decision - ANSWER: In patients with infrequent flareups
(less than three per year), NSAIDs are the first line agent for relieving pain
Gouty Arthritis NSAID Ineffectiveness - ANSWER: Prescribe a glucocorticoid
(prednisone) or make dietary changes
Colchicine Long Term Treatment - ANSWER: Considered for long term treatment if a
person has three or more gouty attacks per year
Colchicine Contraindications - ANSWER: Should not be taken with statins or CYP3A4
inhibitors
Colchicine Adverse Effects - ANSWER: Nausea, vomiting, diarrhea,
myelosuppression, myopathy, and rhabdomyolysis
Allopurinol Long Term Effect - ANSWER: Can lead to severe cutaneous adverse
reaction (SCAR) with symptoms like rash, fever, eosinophilia, and liver and kidney
function issues
Febuxostat Co-Administration - ANSWER: Should be co-administered with NSAIDs
or colchicine
Untreated Gout Complications - ANSWER: Erosion and irreversible joint damage,
renal damage, and tophi formation
Alendronate Patient Education - ANSWER: Minimize risk of esophagitis by
swallowing the pill whole with a full glass of water, then sitting up for at least 30 min, #$%^&*(*
and taking the med 30 min prior to other intake &^%$%^&
*(*&^%$%
Ibandronate Dietary Supplement Interference - ANSWER: Interferes with calcium,
magnesium, and iron absorption ^&*(*&^%
$#$%^&*
Osteoporosis 1st Line Treatment - ANSWER: Alendronate is the first line treatment &^%$#$%
^&*(*&^%
Allopurinol Safety in Renal Dysfunction - ANSWER: Safe to use in patients with renal $#$%^&*
dysfunction or who over produce uric acid
)(*&^%$#
DMARDs Baseline Diagnostics - ANSWER: Includes CBC with WBC differential, s/s %^&*()*&
of infection, malignancies, pregnancy rule out, ALT, AST, serum creatinine, ^%$%^&*
comprehensive history and physical exam, and assessment of immunocompetence and )(*&^%$%
liver and renal status ^&*(*&^%
$%^&*(*&
^%$
