, OUTLINE
I. Pathophysiology of Anemias
II. Pathophysiology of polycytemias
, Anemias
• Anemia : a reduction of the total circulating
red cell mass below normal limits.
• diagnosed based on a reduction in the
hematocrit (the ratio of packed red cells to
total blood volume) and the hemoglobin
concentration of the blood to levels that are
below the normal range.
, Classification
• Morphologic classification
• Microcytic hypochromic anemias
• Macrocytic normochromic anemias
.Etiopathogenic classification
• Normocytic normochromic anemias
1) ↓ed red cell production(↓ed
erythropoiesis)
2) ↑ed red cell destruction(↑ed
hemolysis)