NSCI 175 EXAM 2 QUESTIONS & ANSWERS
Acetylcholine (ACh) is the main transmitter used at which mammalian junctions? -
Answer -neuromuscular junctions
The cholinergic drug atropine _______ receptors.
A. activates nicotinic
B. blocks muscarinic
C. activates muscarinic
D. blocks nicotinic - Answer -B. blocks muscarinic
The NMDA receptor is a type of receptor for the neurotransmitter - Answer -glutamate
In the mammalian brain, the major inhibitory neurotransmitter is - Answer -GABA.
What is microionophoresis?
A. Method of applying small amounts of neurotransmitter candidates to the surface of
neurons
B. Method of miniaturizing the brain for more efficient study
C. Movement of ions over extremely small distances
D. Method of removing small amounts of neurotransmitter from the synaptic terminal -
Answer -A. Method of applying small amounts of neurotransmitter candidates to the
surface of neurons
What does an agonist do? - Answer -mimics the effects of a neurotransmitter
Which of the following statements are true about re-uptake transporters? Select all that
apply.
A. They shuttle transmitter from extracellular fluid to the presynaptic terminal
B. They pack transmitter into synaptic vesicles
C. They are large proteins that span cell membranes
D. They are the molecular site at which many psychoactive drugs work
E. They only transport glutamate - Answer -A. They shuttle transmitter from
extracellular fluid to the presynaptic terminal
C. They are large proteins that span cell membranes
D. They are the molecular site at which many psychoactive drugs work
Which of the following are true about G-protein-coupled receptors? Select all that apply.
, A. They are much slower to work than ionotropic receptors
B. They are activated by antagonists.
C. They are found only in the brain.
D. They contain a neurotransmitter binding site on the extracellular side.
E. An intracellular part of the receptor activates G-proteins.
F. There are only a handful of G-protein-coupled receptors. - Answer -A. They are
much slower to work than ionotropic receptors
D. They contain a neurotransmitter binding site on the extracellular side.
E. An intracellular part of the receptor activates G-proteins.
Which of the following is not a catecholamine neurotransmitter?
A. Serotonin
B. Dopamine
C. Norepinephrine
D. Epinephrine - Answer -A. Serotonin
The dopamine-rich area of the brain that participates in motor control is the ____. -
Answer -Substantia nigra
Dopamine receptors are
A. G-protein coupled receptors that only inhibit adenylyl cyclase
B. Ionotropic receptors that are excitatory
C. G-protein coupled receptors that only activate adenylyl cyclase
D. G-protein coupled receptors that can either activate or inhibit adenylyl cyclase -
Answer -D. G-protein coupled receptors that can either activate or inhibit adenylyl
cyclase
The area of the brain that makes norepinephrine is the - Answer -locus coeruleus
Which neurotransmitter is synthesized and released by the raphe nuclei? - Answer -
serotonin
SSRIs act on which protein? - Answer -serotonin transporter
Peptide neurotransmitters differ from small molecule neurotransmitters in which of the
following ways: (select all that apply)
A. peptide NTs are made in the soma small molecule NTs are made in the terminal
B. peptide NTs don't have transporters and most small molecule NTs do
Acetylcholine (ACh) is the main transmitter used at which mammalian junctions? -
Answer -neuromuscular junctions
The cholinergic drug atropine _______ receptors.
A. activates nicotinic
B. blocks muscarinic
C. activates muscarinic
D. blocks nicotinic - Answer -B. blocks muscarinic
The NMDA receptor is a type of receptor for the neurotransmitter - Answer -glutamate
In the mammalian brain, the major inhibitory neurotransmitter is - Answer -GABA.
What is microionophoresis?
A. Method of applying small amounts of neurotransmitter candidates to the surface of
neurons
B. Method of miniaturizing the brain for more efficient study
C. Movement of ions over extremely small distances
D. Method of removing small amounts of neurotransmitter from the synaptic terminal -
Answer -A. Method of applying small amounts of neurotransmitter candidates to the
surface of neurons
What does an agonist do? - Answer -mimics the effects of a neurotransmitter
Which of the following statements are true about re-uptake transporters? Select all that
apply.
A. They shuttle transmitter from extracellular fluid to the presynaptic terminal
B. They pack transmitter into synaptic vesicles
C. They are large proteins that span cell membranes
D. They are the molecular site at which many psychoactive drugs work
E. They only transport glutamate - Answer -A. They shuttle transmitter from
extracellular fluid to the presynaptic terminal
C. They are large proteins that span cell membranes
D. They are the molecular site at which many psychoactive drugs work
Which of the following are true about G-protein-coupled receptors? Select all that apply.
, A. They are much slower to work than ionotropic receptors
B. They are activated by antagonists.
C. They are found only in the brain.
D. They contain a neurotransmitter binding site on the extracellular side.
E. An intracellular part of the receptor activates G-proteins.
F. There are only a handful of G-protein-coupled receptors. - Answer -A. They are
much slower to work than ionotropic receptors
D. They contain a neurotransmitter binding site on the extracellular side.
E. An intracellular part of the receptor activates G-proteins.
Which of the following is not a catecholamine neurotransmitter?
A. Serotonin
B. Dopamine
C. Norepinephrine
D. Epinephrine - Answer -A. Serotonin
The dopamine-rich area of the brain that participates in motor control is the ____. -
Answer -Substantia nigra
Dopamine receptors are
A. G-protein coupled receptors that only inhibit adenylyl cyclase
B. Ionotropic receptors that are excitatory
C. G-protein coupled receptors that only activate adenylyl cyclase
D. G-protein coupled receptors that can either activate or inhibit adenylyl cyclase -
Answer -D. G-protein coupled receptors that can either activate or inhibit adenylyl
cyclase
The area of the brain that makes norepinephrine is the - Answer -locus coeruleus
Which neurotransmitter is synthesized and released by the raphe nuclei? - Answer -
serotonin
SSRIs act on which protein? - Answer -serotonin transporter
Peptide neurotransmitters differ from small molecule neurotransmitters in which of the
following ways: (select all that apply)
A. peptide NTs are made in the soma small molecule NTs are made in the terminal
B. peptide NTs don't have transporters and most small molecule NTs do
