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CBSE NBME REAL EXAM PRACTICE QUESTIONS
AND 100% CORRECT ANSWERS GRADED A+
TESTED AND APPROVED!!!
What happens as blood-gas coefficient increases (more potent) ---- ANSWER----MAC
decreases
AE of inhaled anesthetics (halothane) ---- ANSWER----hepatotoxic (p450) increase
aminotransferase
*increase PT * leukocytosis
*eosinophilia*
What is the impact of halogenated inhaled anesthetics ---- ANSWER----increase cerebral
blood flow
tx Malignant Hyperthermia ---- ANSWER----Dantrolene
- decrease Ca release in sarcolemma
Malignant hyperthermia is caused by ---- ANSWER----person with *atypical
pseudocholinsterase *
DRUGS:
halothane, succinylcholine, decamethonium
, 2
Alteplase ---- ANSWER----tPA activates
plasmin to lyse clots
AE of tPA/Alteplase ---- ANSWER----intracranial hemorrhage
giving packed RBC can cause ---- ANSWER----paresthesia in extremities
has *citrate* which chelates Ca
= decreased Ca
If person has *heparin induced thrombocytopenia* what should you use ---- ANSWER---
Argatroban
- direct thrombin inhibitor
Cilostazol ---- ANSWER----inhibit platelet function (PKA) direct
vasodilation
(tx: claudication)
Cilostazol tx ---- ANSWER----claudication
homocysteine
-->
Methionine requires: ----
ANSWER----*B12* Me-THF
from *folate* cycle How to
prevent intracranial hemorrhage
,in newborn ---- ANSWER----vit
K
BPH tx ---- ANSWER----*finasteride* (5a red inhibitor)
*leuprolide* (GnRH)
*"-azosin"* (a1 block)
Finasteride ---- ANSWER----5a-reductase inhibitor tx
BPH and baldness
pulsatile Leuprolide ---- ANSWER----GnRH = rise LH/T
continuous Leuprolide ---- ANSWER----GnRH = decrease T/DHT
inhibit *androgen receptor binding* ---- ANSWER----flutamide
cyproterone spironolactone
Leuprolide +
Antagonsist to androgen receptor ---- ANSWER----initial transient rise in LH/T from
leuprolide, so administer with
*flutamide, cyproterone, spironolactone *
tx prostate cancer
"-azosin" ---- ANSWER----a1 block
, 4
tx BPH and HTN
BPH can cause what on bladder ---- ANSWER----bladder outlet obstruction
--> parenchymal atrophy
--> CKD !!!
tx PCOS with ---- ANSWER----OCP
- suppress LH
- decrease androgen production
PCOS pt who wants to get pregnant ---- ANSWER----*Clomiphene*
- selective ER modulator
= prevent negative feedback
OSA causes ---- ANSWER----pulmonary HTN and RHF increases
EPO which worsens HTN
EPO can do what on Cardiovascular ----
ANSWER----worsen HTN
Pulmonary Arterial HTN ---- ANSWER----*BMPR2*
High *endothelin*, Low NO
SMC hypertophy, fibrosis, narrow lumen
*P2 louder* than A2
CBSE NBME REAL EXAM PRACTICE QUESTIONS
AND 100% CORRECT ANSWERS GRADED A+
TESTED AND APPROVED!!!
What happens as blood-gas coefficient increases (more potent) ---- ANSWER----MAC
decreases
AE of inhaled anesthetics (halothane) ---- ANSWER----hepatotoxic (p450) increase
aminotransferase
*increase PT * leukocytosis
*eosinophilia*
What is the impact of halogenated inhaled anesthetics ---- ANSWER----increase cerebral
blood flow
tx Malignant Hyperthermia ---- ANSWER----Dantrolene
- decrease Ca release in sarcolemma
Malignant hyperthermia is caused by ---- ANSWER----person with *atypical
pseudocholinsterase *
DRUGS:
halothane, succinylcholine, decamethonium
, 2
Alteplase ---- ANSWER----tPA activates
plasmin to lyse clots
AE of tPA/Alteplase ---- ANSWER----intracranial hemorrhage
giving packed RBC can cause ---- ANSWER----paresthesia in extremities
has *citrate* which chelates Ca
= decreased Ca
If person has *heparin induced thrombocytopenia* what should you use ---- ANSWER---
Argatroban
- direct thrombin inhibitor
Cilostazol ---- ANSWER----inhibit platelet function (PKA) direct
vasodilation
(tx: claudication)
Cilostazol tx ---- ANSWER----claudication
homocysteine
-->
Methionine requires: ----
ANSWER----*B12* Me-THF
from *folate* cycle How to
prevent intracranial hemorrhage
,in newborn ---- ANSWER----vit
K
BPH tx ---- ANSWER----*finasteride* (5a red inhibitor)
*leuprolide* (GnRH)
*"-azosin"* (a1 block)
Finasteride ---- ANSWER----5a-reductase inhibitor tx
BPH and baldness
pulsatile Leuprolide ---- ANSWER----GnRH = rise LH/T
continuous Leuprolide ---- ANSWER----GnRH = decrease T/DHT
inhibit *androgen receptor binding* ---- ANSWER----flutamide
cyproterone spironolactone
Leuprolide +
Antagonsist to androgen receptor ---- ANSWER----initial transient rise in LH/T from
leuprolide, so administer with
*flutamide, cyproterone, spironolactone *
tx prostate cancer
"-azosin" ---- ANSWER----a1 block
, 4
tx BPH and HTN
BPH can cause what on bladder ---- ANSWER----bladder outlet obstruction
--> parenchymal atrophy
--> CKD !!!
tx PCOS with ---- ANSWER----OCP
- suppress LH
- decrease androgen production
PCOS pt who wants to get pregnant ---- ANSWER----*Clomiphene*
- selective ER modulator
= prevent negative feedback
OSA causes ---- ANSWER----pulmonary HTN and RHF increases
EPO which worsens HTN
EPO can do what on Cardiovascular ----
ANSWER----worsen HTN
Pulmonary Arterial HTN ---- ANSWER----*BMPR2*
High *endothelin*, Low NO
SMC hypertophy, fibrosis, narrow lumen
*P2 louder* than A2
