Complete 150 Questions And Correct Answers
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Kallmann's syndrome - labs
Decreased FSH, LH, estrogen, testosterone
Kallmann's syndrome - imaging
MRI head - absence of olfactory bulbs & olfactory sulci
Kallmann's syndrome - treatment
Exogenous testosterone, OCPs
Fertility restored w/ exogenous GnRH pump with pulsatile release
Medications most likely to cause serum-sickness like reaction
Amoxicillin
Penicillin
Cefaclor
TMP-SMX
Serum sickness like reaction - presentation (5)
Urticarial rash
Fever
Polyarthralgias / polyarthritis
Malaise
6-12 days after exposure
Absence seizure - EEG
3Hz spike and wave
,Absence seizure - treatment
Ethosuximide
Dermatophytosis - presentation
Erythematous, scaling, plaque-like lesion with central clearing
- look for sick contacts
"Ringworm"
"Tinea corporis"
Tracheoesophageal fistula - presentation
Excessive secretions
Respiratory distress
Inability to feed
Feeding catheter curled in esophagus on x-ray
X-linked agammaglobulinemia - labs
Decreased IgG
Decreased mature CD-19 (B) cells
X-linked agammaglobulinemia - pathophysiology
Absence of Bruton's tyrosine kinase --> inability of B cells to mature
Contraindications to DTaP vaccine
Serious allergic / anaphylactic reaction
Encephalopathy w/i 7 days
Pyloric stenosis - associated electrolyte imbalance
Hypochloremia
Maternal diabetes - electrolyte abnormalities in newborns
Hypoglycemia (d/t hyperinsulinemia)
Hypocalcemia (a/w low PTH)
Hypomagnesemia
Coin lodged in the esophagus will be facing
AP (forward, en face)
Coin lodged in the trachea will be facing
,Laterally
Pertussis - management
14 days macrolide antibiotic (e.g., erythromycin) for patient and family
Pertussis - presentation
1-2 week catarrhal phase presenting like URI, followed by paroxysmal phase with whooping
cough and posttussive emesis
Beckwith-Wiedemann - presentation (8)
Overgrowth
Macroglossia
Anterior abdominal wall defect
Hepatomegaly
Pitting of external ears
Neonatal hypoglycemia
Mental retardation
Embryonal tumors
Bartter syndrome - pathophysiology
Defective chloride channels
Defective Na reabsorption in thick ascending limb of loop of Henle --> hypovolemia -->
activation of renin-angiotensin-aldosterone system
Bartter syndrome - presentation
Polyhydramnios
Prematurity
Neonatal:
Massive polyuria
FTT
Some have sensorineural deafness
Classical;
Polyuria, polydipsia
FTT
, Carpopedal spasm
Developmental delay
Bartter syndrome - labs
Severe hypokalemia
Hypochloremia
Metabolic alkalosis
Bun:Cr > 20 (hypovolemia)
Gitelman syndrome - pathophysiology
High urinary excretion of magnesium
Low urinary excretion of calcium
Gitelman syndrome - labs
Hypochloremia
Hypokalemia
Metabolic alkalosis
Gullner syndrome - pathophysiology
Familial hypokalemic alkalosis d/t proximal tube defect --> hypouricemia
Liddle syndrome - pathophysiology
Dysregulation of ENaC channel in proximal tubule --> increased sodium absorption and
increased potassium secretion
Liddle syndrome - labs
Hypokalemia
Metabolic alkalosis
Decreased serum renin & aldosterone
Hypertension
Drugs that cause hemolysis in G6PD deficiency (7)
Sulfonamides
Nitrofurantoin
Primaquine
Dimercaprol
Aspirin