UNCONJUGATED HYPERBILIRUBINEMIA
① ↑↑ Bilirubin production
(Pre-hepatic/ Acholuric/ Hemolytic
↓
jaundice
Bilirubin absent in urive
[
excessive breakdown
in of
witra and Seres cent RBCs
extravasculal 2
hemolysis ↑
Haemoglobin production
2
#
Bilirus in production
f -
when exceeds the capacity of
bilirubin
liver to
conjugate
↓
hyperbilirubinemia develops
In
-
infants
Breakdown
of RBCs
high
↑
>
-
:
in
>
-
enzymes for bilirubir conjugation
, L wier :
deficient
↳ also cause un
conjugated hyperbilirubinemia
called icterus neonatorum
↓
brain
danger of damage
if bilirubin
unconjugated
LABORATORY DATA
> 20
mg/dL
① serum transaminases : normal
② alkaline phosphatase : normal
③ serum protein : normal
① faces : dark brown coloured
Bile excreted in faces
pigments
are
⑤ wive Bile
pigments absent
:
Bilirubin absent
wrobilingen present
① ↑↑ Bilirubin production
(Pre-hepatic/ Acholuric/ Hemolytic
↓
jaundice
Bilirubin absent in urive
[
excessive breakdown
in of
witra and Seres cent RBCs
extravasculal 2
hemolysis ↑
Haemoglobin production
2
#
Bilirus in production
f -
when exceeds the capacity of
bilirubin
liver to
conjugate
↓
hyperbilirubinemia develops
In
-
infants
Breakdown
of RBCs
high
↑
>
-
:
in
>
-
enzymes for bilirubir conjugation
, L wier :
deficient
↳ also cause un
conjugated hyperbilirubinemia
called icterus neonatorum
↓
brain
danger of damage
if bilirubin
unconjugated
LABORATORY DATA
> 20
mg/dL
① serum transaminases : normal
② alkaline phosphatase : normal
③ serum protein : normal
① faces : dark brown coloured
Bile excreted in faces
pigments
are
⑤ wive Bile
pigments absent
:
Bilirubin absent
wrobilingen present
