Summary Jaundice – Pathophysiology & Classification (MBBS Notes)

JAUNDICE
-

yellow pigmentation
to
of
↑*
skin ,
solera due

bilirubi

Hepatic bilecauses -




>
-

emulsification of fats
cholestrol bilirubin
excretion excess
of
,
>
-




↓ xenobiotics etc .


with this
interfere
and icterus
causejaundice
later lead to cholestasis
and




causes of jaundice -
↓ ↓
Obstruction in increased hepatocyte O




&




ble bilirubir dysfaction
flow
of O



store production hepatitis
gall
due to

extravascular

red cell
hemolysis

, BILIRUBIN AND BILE FORMATION




-heme Themelease
Bermon
Senescent
red cells source


a

·
with albumin
conjugates
Y↳ Bilirubin + one/two




⑧
- glucuronidesUDP
bilirubir
by
glucuronye-
8




gucuronides
-


transferase

repatocyte