chemo drug that Affects replicating cells but not resting cells; Decreased cell
damage, side and toxic effects
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Cell cycle specific chemo
, Alterations in proliferation - escape from normal cellular control mechanism that
result in cellular dysplasia (change in size, shape or arrangement of cells) and
anaplasia (regression of cells to a more primitive type)
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Pathophysiology of cancer
cancer causing agents; can be genotoxic (cause irreversible genetic change in cells);
can act as promoters
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Carcinogens
cancer complication; Increased secretion of ADH by some cancers such as lung, GI
and adrenal cancers; fluid overload and severe hyponatremia; Wt gain, nausea,
vomiting, weakness, personality changes, seizures & coma = cerebral edema.
Treatment--fluid restriction and 3% NaCl infusion if severe
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SIADH
risks include genetic factors, age > 50 yrs, Hx IBS, diet high in fat/calories. Manifests as
signs of decreased organ function (labs), obstruction or compression of adjacent
damage, side and toxic effects
Give this one a try later!
Cell cycle specific chemo
, Alterations in proliferation - escape from normal cellular control mechanism that
result in cellular dysplasia (change in size, shape or arrangement of cells) and
anaplasia (regression of cells to a more primitive type)
Give this one a try later!
Pathophysiology of cancer
cancer causing agents; can be genotoxic (cause irreversible genetic change in cells);
can act as promoters
Give this one a try later!
Carcinogens
cancer complication; Increased secretion of ADH by some cancers such as lung, GI
and adrenal cancers; fluid overload and severe hyponatremia; Wt gain, nausea,
vomiting, weakness, personality changes, seizures & coma = cerebral edema.
Treatment--fluid restriction and 3% NaCl infusion if severe
Give this one a try later!
SIADH
risks include genetic factors, age > 50 yrs, Hx IBS, diet high in fat/calories. Manifests as
signs of decreased organ function (labs), obstruction or compression of adjacent
