RN RELIAS PHARMACOLOGY ACTUAL
EXAM QUESTIONS WITH VERIFIED
SOLUTIONS LATEST UPDATE TESTED
AND APPROVED!!!
What are antacids? -- ANSWER--Antacids are a group of inorganic chemicals
that neutralize stomach acid.
Antacids are available OTC, and many patients use them to self-treat a variety
of GI symptoms.
The choice of an antacid depends on adverse effects and absorption factors.
Antacids Therapeutic actions -- ANSWER--The desired actions of antacids
include the following:
Neutralize stomach acid by direct chemical reaction.
Symptomatic relief of an upset stomach associated with hyperacidity, as well as
the hyperacidity associated with peptic ulcer, gastritis, peptic esophagitis,
gastric hyperacidity, and hiatal hernia.
Antacids Contraindications and Cautions -- ANSWER--The following are
contraindications and cautions when using antacids:
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Allergy. The antacids are contraindicated in the presence of any known allergy
to antacid products or any component of the drug to prevent hypersensitivity
reactions.
Co-morbidities. Caution should be used in the following instances: any
condition that can be exacerbated by electrolyte or acid-based imbalance to
prevent exacerbations and serious adverse effects; any electrolyte imbalance ,
which could be exacerbated by the electrolytechanging effects of these drugs;
GI obstruction which could cause systemic absorption of the drugs and increase
adverse effects; renal dysfunction, which could lead to electrolyte disturbance if
any absorbed antacid is neutralized properly.
Pregnancy and lactation. Antacids are contraindicated for pregnant and lactating
women because of the potential for adverse effects on the fetus or neonate.
Proton Pump Inhibitors -- ANSWER--The gastric acid pump or proton pump
inhibitors suppress gastric acid secretion by specifically inhibiting the
hydrogen-potassium adenosine triphosphate enzyme system on the secretory
surface of the gastric parietal cells.
Proton Pump Inhibitors: Generic and Brand Names -- ANSWER--Here is a table
of the most commonly encountered proton pump inhibitor:
Classification Generic name Brand name Proton pump
inhibitorsdexlansoprazoleKapidexesomeprazoleNexiumlansoprazolePrevacidom
eprazolePrilo secpantoprazole Protonixrabeprazole Aciphex
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What are Proton Pump Inhibitors? -- ANSWER--Proton pump inhibitors
suppress the secretion of hydrochloric acid into the lumen of the stomach.
Antacids -- ANSWER--Antacids are used to chemically react with and
neutralize the acid in the stomach. They can provide rapid relief from increased
acid levels. They are known to cause GI alterations such as diarrhea or
constipation and can alter the absorption of many drugs.
Antacids: Generic and Brand Names -- ANSWER--Here is a list of the most
commonly encountered antacids and their brand names.
Classification Generic name Brand name Antacidsaluminum salts
AlternaGELcalcium saltsOystercal, TumsmagaldrateLosopan,
Riopanmagnesium saltsMilk of Magnesia, otherssodium bicarbonateBell-ans
Histamine-2 (H2) receptor antagonists -- ANSWER--Histamine-2 (H2) receptor
antagonists block the release of acid in response to gastrin or parasympathetic
release.
Histamine-2 Antagonist: Generic and Brand Names -- ANSWER--Here is a
table of the most commonly used H2 antagonists.
ClassificationGeneric nameBrand nameHistamine-2
antagonistscimetidineTagametranitidineZantacfamotidinePepcidnizatidineAxid
H2 blockers Therapeutic actions -- ANSWER--The desired actions of H2
antagonists include the following: