Immunity -
Innate/ familial / genetic
Acquired
Human health and disease
Ability of body to fight against disease causing organism (pathogen) z
Antibody -glycoproteins
-H L "
Heavy chain- 450 AA
Light chain -220 AA
2. Allergy
-Hypersensitivity immune response (exag
-
22
-IgE Allergen Vasodilation
o
J Histamine
Innate immunity: by birth
-
Cytokine Epitope Bronchiocon
↓
Paratope
- Mast cell
V barrier
Physical - Physiological -interferon
Trea
barrier Cellular Variable
Types
p
barrier part
F -Ant
barrier — lysozyme: tears
[AB)
-Hay fever: pollen( URTI)
-Ste
-
-skin: stratum -stomach: HCL
2 C
Constant
-Asthma: LRTI
-PMN:
corneum -Anaphylactic shock : penicillin intake
- mucus
polymorphonuclear -oil from sebaceous Anti viral protein
region
F
Mast cell — histamine— vasodilation— BPd— death
<
-Adr
lymphocyte glands AVP
membrane: [
9 -monocyte -cerumen: ear wax
digestive ,
-macrophages: Classes of antibody( immunoglobulin)
respiratorys,
phagocytosis
-Sweat from sweat 3. Graft rejection
urino-genital gland -Recipient immune system act against gr
-natural killer
system
cells(NK cells) IgD IgM -CMI( T-Cell) mediated
IgA - membrane bound IgE
-2 paratope
IgG -largest antibody Treatment: immunosuppressant( cyclospor
-Allergic -pentamer
Acquired immunity: acquired during lifetime, -2nd most abundant -Most abundant reaction 10 paratope
(15 - 20%) (75%)
present only vertebrates -secretory antibody -Monomer,
-Primary response
Health
Fi
1. Specificity -Copro antibody 2 paratope According to WHO :
-cross placenta
2. Diversity. -Colostrum (Milk)
-2°response
Complete physical, ,mental and social well be
-Dimer
3. Discrimination from self and non-self. -4 paratope Good humor hypothesis (greek scientists, Hippocra
Functions of antibodies
4. Memory. Health - balance of certain ‘humor’
Agglutination opsonisation neutralisation compliment mediated lysis
Lymphoid organ William Harvey
disapproved Phlegmn Yellow bile
Primary and secondary immune response (By sp
/cough (Liver)
7 Primary Anamnestic
- during 1st attack of -Subsequent/second
Organs where B and T cell response. Health affected by:
antigen attack of antigen
Eg. bone marrow, Thymus
Secondary -m
Antigen Su
Originate
specific
-Weak
-Take longer time
-heightened
-Take shorter time
1. Genetic disorder
2. Lifestyle
B and T cell, differentiate and proliferate here
- -
-IgM -IgG 3. Infections
Eg.Tonsils
Lymph nodes: trap antigen from local tissue
Disease
Spleen : trap blood borne antigen Active immunity Passive immunity Congenital
Peyer’s patches : intestine - when body’s own cells -preformed antibodies are -present since birth -Gained
MALT (mucosa associated lymph tissue) start forming antibody given to individual Down syndrome
-Long lasting L
Types of acquired immunity -Not long lasting Non-communicable Comm
Types Types Non-Infectious
Humoral Immunity Cell mediated immunity Natural Artificial — this is that spr
Natural Artificial — Disease which do not
infected to health
Innate/ familial / genetic
Acquired
Human health and disease
Ability of body to fight against disease causing organism (pathogen) z
Antibody -glycoproteins
-H L "
Heavy chain- 450 AA
Light chain -220 AA
2. Allergy
-Hypersensitivity immune response (exag
-
22
-IgE Allergen Vasodilation
o
J Histamine
Innate immunity: by birth
-
Cytokine Epitope Bronchiocon
↓
Paratope
- Mast cell
V barrier
Physical - Physiological -interferon
Trea
barrier Cellular Variable
Types
p
barrier part
F -Ant
barrier — lysozyme: tears
[AB)
-Hay fever: pollen( URTI)
-Ste
-
-skin: stratum -stomach: HCL
2 C
Constant
-Asthma: LRTI
-PMN:
corneum -Anaphylactic shock : penicillin intake
- mucus
polymorphonuclear -oil from sebaceous Anti viral protein
region
F
Mast cell — histamine— vasodilation— BPd— death
<
-Adr
lymphocyte glands AVP
membrane: [
9 -monocyte -cerumen: ear wax
digestive ,
-macrophages: Classes of antibody( immunoglobulin)
respiratorys,
phagocytosis
-Sweat from sweat 3. Graft rejection
urino-genital gland -Recipient immune system act against gr
-natural killer
system
cells(NK cells) IgD IgM -CMI( T-Cell) mediated
IgA - membrane bound IgE
-2 paratope
IgG -largest antibody Treatment: immunosuppressant( cyclospor
-Allergic -pentamer
Acquired immunity: acquired during lifetime, -2nd most abundant -Most abundant reaction 10 paratope
(15 - 20%) (75%)
present only vertebrates -secretory antibody -Monomer,
-Primary response
Health
Fi
1. Specificity -Copro antibody 2 paratope According to WHO :
-cross placenta
2. Diversity. -Colostrum (Milk)
-2°response
Complete physical, ,mental and social well be
-Dimer
3. Discrimination from self and non-self. -4 paratope Good humor hypothesis (greek scientists, Hippocra
Functions of antibodies
4. Memory. Health - balance of certain ‘humor’
Agglutination opsonisation neutralisation compliment mediated lysis
Lymphoid organ William Harvey
disapproved Phlegmn Yellow bile
Primary and secondary immune response (By sp
/cough (Liver)
7 Primary Anamnestic
- during 1st attack of -Subsequent/second
Organs where B and T cell response. Health affected by:
antigen attack of antigen
Eg. bone marrow, Thymus
Secondary -m
Antigen Su
Originate
specific
-Weak
-Take longer time
-heightened
-Take shorter time
1. Genetic disorder
2. Lifestyle
B and T cell, differentiate and proliferate here
- -
-IgM -IgG 3. Infections
Eg.Tonsils
Lymph nodes: trap antigen from local tissue
Disease
Spleen : trap blood borne antigen Active immunity Passive immunity Congenital
Peyer’s patches : intestine - when body’s own cells -preformed antibodies are -present since birth -Gained
MALT (mucosa associated lymph tissue) start forming antibody given to individual Down syndrome
-Long lasting L
Types of acquired immunity -Not long lasting Non-communicable Comm
Types Types Non-Infectious
Humoral Immunity Cell mediated immunity Natural Artificial — this is that spr
Natural Artificial — Disease which do not
infected to health
