Pathophysiology,
6th Edition Huether &
Y Y Y Y
McCance Test Bank.
Y Y
, UnderstandingYPathophysiologyY6thYEditionYHuetherYTestYBan
k
Chapter 01: Cellular Biology
Y Y Y
Huether & McCance: Understanding Pathophysiology, 6th Edition
Y Y Y Y Y Y
MULTIPLEYCHOICE
1. AYstudentYisYobservingYaYcellYunderYtheYmicroscope.YItYisYobservedYtoYhaveYsupercoiledYDN
AYwithYhistones.YWhichYofYtheYfollowingYwouldYalsoYbeYobservedYbyYtheYstudent?
a. AYsingleYcircularYchromosome
b. AYnucleus
c. Free-floatingYnuclearYmaterial
d. NoYorganelles
ANS:Y B
TheYcellYdescribedYisYaYeukaryoticYcell,YsoYitYhasYhistonesYandYaYsupercoiledYDNAYwithinYitsYn
ucleus;Ythus,YtheYnucleusYshouldYbeYobserved.YAYsingleYcircularYchromosomeYcalledYaYprokar
yoteYcontainsYfree-floatingYnuclearYmaterialYbutYhasYnoYorganelles.
REF:Y p.Y2
2. AYnurseYisYinstructingYtheYstaffYaboutYcellularYfunctions.YWhichYcellularYfunctionYisYtheYnurs
eYdescribingYwhenYanYisolatedYcellYabsorbsYoxygenYandYusesYitYtoYtransformYnutrientsYtoYener
gy?
a. MetabolicYabsorption
b. Communication
c. Secretion
d. Respiration
ANS:Y D
TheYcell’sYabilityYtoYabsorbYoxygenYisYreferredYtoYasYrespirationYwhileYitsYcommunicationYabilityY
involvesYmaintenanceYofYaYsteadyYdynamicYstate,YmetabolicYabsorptionYprovidesYnutrition,YandY
secretionYallowsYforYtheYsynthesizingYofYnewYsubstances.
REF:Y p.Y2
3. AYeukaryoticYcellYisYundergoingYDNAYreplication.YInYwhichYregionYofYtheYcellYwouldYmostY
ofYtheYgeneticYinformationYbeYcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusYCytoplasm
ANS:Y C
TheYregionYofYtheYcellYthatYcontainsYgeneticYmaterial,YincludingYaYlargeYamountYofYribonuclei
cYacid,YmostYofYtheYDNA,YandYDNA-
bindingYproteins,YisYtheYnucleolus,YwhichYisYlocatedYwithinYtheYcell’sYnucleus.YMitochondriaYi
sYassociatedYwithYcellularYrespiration,YwhileYribosomesYareYinvolvedYwithYproteinYmanufactu
ring.YCytoplasmYisYaYfluidYfillingYthatYisYaYcomponentYofYtheYcell.
REF:Y p.Y2
NURSINGTB.COM
, UnderstandingYPathophysiologyY6thYEditionYHuetherYTestYBan
k
4. WhichYofYtheYfollowingYcanYremoveYproteinsYattachedYtoYtheYcell’sYbilayerYbyYdissolvingYt
heYlayerYitself?
a. PeripheralYmembraneYproteins
b. IntegralYmembraneYproteins
c. Glycoproteins
d. CellYadhesionYmolecules
ANS:Y B
ProteinsYdirectlyYattachedYtoYtheYmembraneYbilayerYcanYbeYremovedYbyYtheYactionYofYintegralY
membraneYproteinsYthatYdissolveYtheYbilayer.YPeripheralYmembraneYproteinsYresideYatYtheYsur
faceYwhileYcellYadhesionYmoleculesYareYonYtheYoutsideYofYtheYmembrane.YGlycoproteinYmarks
YcellsYandYdoesYnotYfloat.
REF:Y p.Y7
5. WhichYofYtheYfollowingYcanYbindYtoYplasmaYmembraneYreceptors?
a. Oxygen
b. Ribosomes
c. AmphipathicYlipids
d. Ligands
ANS:Y D
LigandsYareYtheYonlyYspecificYmoleculesYthatYcanYbindYwithYreceptorsYonYtheYcellYmembrane.
REF:Y p.Y9
6. AYnurseYisYreviewingYaYreportYfromYaYpatientYwithYmetastaticYcancer.YWhatYalternationYinYthe
a. DecreasedYfibronectin
b. IncreasedYcollagen
c. DecreasedYelastin
d. IncreasedYglycoproteins
ANS:Y A
OnlyYaYreducedYamountYofYfibronectinYisYfoundYinYsomeYtypesYofYcancerousYcells,YallowingYth
emYtoYtravelYorYmetastasize.
REF:Y p.Y10
7. WhichYformYofYcellYcommunicationYisYusedYtoYrelateYtoYotherYcellsYinYdirectYphysicalYcontact?
a. CellYjunction
b. GapYjunction
c. Desmosome
d. TightYjunction
ANS:Y A
CellYjunctionsYholdYcellsYtogetherYandYpermitYmoleculesYtoYpassYfromYcellYtoYcell.
GapYjunctionsYallowYforYcellularYcommunicationYbetweenYcells.YNeitherYdesmosomesYnorYtightYj
unctionsYareYassociatedYwithYcellularYcommunication.
REF:Y p.Y11
NURSINGTB.COM
, UnderstandingYPathophysiologyY6thYEditionYHuetherYTestYBan
k
8. PancreaticYbetaYcellsYsecreteYinsulin,YwhichYinhibitsYsecretionYofYglucagonYfromYneighborin
gYalphaYcells.YThisYactionYisYanYexampleYofYwhichYofYtheYfollowingYsignalingYtypes?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:Y A
ParacrineYsignalingYinvolvesYtheYreleaseYofYlocalYchemicalYmediatorsYthatYareYquicklyYtakenYup,Y
destroyed,YorYimmobilized,YasYinYtheYcaseYofYinsulinYandYtheYinhibitionYofYtheYsecretionYofYgluca
gon.YNoneYofYtheYotherYoptionsYinvolveYsignalingYthatYisYassociatedYwithYaYlocalYchemicalYmedia
torYlikeYinsulin.
REF:Y p.Y12
9. InYcellularYmetabolism,YeachYenzymeYhasYaYhighYaffinityYforYa:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS:Y B
EachYenzymeYhasYaYhighYaffinityYforYaYsubstrate,YaYspecificYsubstanceYconvertedYtoYaYproductY
ofYtheYreaction.YCellularYmetabolismYisYnotYdependentYonYanYattractionYbetweenYanYenzymeYa
ndYanyYofYtheYremainingYoptions.
REF:YYYp.Y1
6 NURSINGTB.COM
10. AnYathleteYrunsYaYmarathon,YafterYwhichYhisYmusclesYfeelYfatiguedYandYunableYtoYcontract.YTh
eYathleteYasksYtheYnurseYwhyYthisYhappened.YTheYnurse’sYresponseYisYbasedYonYtheYknowledgeY
thatYtheYproblemYisYresultYofYaYdeficiencyYof:
a. GTP
b. AMP
c. ATP
d. GMP
ANS:Y C
WhenYATPYisYdeficient,YimpairedYmuscleYcontractionYresults.YNoneYofYtheYotherYoptionsYareYinv
olvedYinYmuscleYcontraction.
REF:Y p.Y16
11. WhichYphaseYofYcatabolismYproducesYtheYmostYATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. CitricYacidYcycle
ANS:Y D
WhileYsomeYATPYisYproducedYduringYtheYoxidationYandYglycolysisYphases,YmostYofYtheYATP
YisY
generatedYduringYtheYcitricYacidYcycle.YDigestionYdoesYnotYproduceYanyYATP.
NURSINGTB.COM