Scholar Notes
Clear · Concise · Exam-Ready
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Biochemistry Notes
Topic: Glycolysis
✓ Also called Embden–Meyerhof Pathway (E.M.
Pathway)
✓ Detailed explanation with definitions &
reactions
✓ Covers anaerobic & aerobic glycolysis
✓ Location of glycolysis and overall reaction
included
✓ Suitable for BS Chemistry, Biochemistry, and Pre-
Medical students
, Glycolysis
▪ Also called Embden - Meyerhof pathway (E.M. Pathway)
▪ Glycolysis is the major pathway for utilization of glucose in
the body
Glycolysis is defined as: " A regulated series of reactions for
converting glucose to pyruvate producing "ATP "
▪ Anaerobic Glycolysis - occurs in absence of oxygen - lead to
lactate
▪ Aerobic Glycolysis - Glycolysis in presence of oxygen - lead
to pyruvate (end product)
Location:
Glycolysis occurs in the cytoplasm of the cell (cytosol)
Overall reaction:
Glucose + 2ADP + 2Pi + 2NAD+
↓
2 pyruvate + 2ATP + 2NADH + 2 H+ +H2O
Regulation of Glycolysis:
The three enzymes (Glucokinase/Hexokinase, phosphofructokinase and
pyruvate kinase) catalysing the irreversible reaction regulate glycolysis.
Hexokinase/Glucokinase:
Glucose is converted into Glucose 6- phosphate by hexokinase.
Clear · Concise · Exam-Ready
---
Biochemistry Notes
Topic: Glycolysis
✓ Also called Embden–Meyerhof Pathway (E.M.
Pathway)
✓ Detailed explanation with definitions &
reactions
✓ Covers anaerobic & aerobic glycolysis
✓ Location of glycolysis and overall reaction
included
✓ Suitable for BS Chemistry, Biochemistry, and Pre-
Medical students
, Glycolysis
▪ Also called Embden - Meyerhof pathway (E.M. Pathway)
▪ Glycolysis is the major pathway for utilization of glucose in
the body
Glycolysis is defined as: " A regulated series of reactions for
converting glucose to pyruvate producing "ATP "
▪ Anaerobic Glycolysis - occurs in absence of oxygen - lead to
lactate
▪ Aerobic Glycolysis - Glycolysis in presence of oxygen - lead
to pyruvate (end product)
Location:
Glycolysis occurs in the cytoplasm of the cell (cytosol)
Overall reaction:
Glucose + 2ADP + 2Pi + 2NAD+
↓
2 pyruvate + 2ATP + 2NADH + 2 H+ +H2O
Regulation of Glycolysis:
The three enzymes (Glucokinase/Hexokinase, phosphofructokinase and
pyruvate kinase) catalysing the irreversible reaction regulate glycolysis.
Hexokinase/Glucokinase:
Glucose is converted into Glucose 6- phosphate by hexokinase.
