BOC Immunology exam questions with answers

BOC Immunology exam questions with
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answers

What are antinuclear antibody tests used for?
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a. To determine sensitivities for microbiology
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b. To diagnose anemias
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c. To diagnose lupus erythematosus
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d. To determine PCR analysis - CORRECT ANSWERS ✔✔c
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SLE patients often have:
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a. High titers of antimitochondrial antibody
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b. Decrease immunoglobulin levels
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c. Hight tiers of anti-smooth muscle antibodies
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d. High tiers of DNA antibody - CORRECT ANSWERS ✔✔d
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Rheumatoid factor reacts with: |\ |\ |\




a. Latex particles coated with an inert substance
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b. Kinetoplasts of Crithidia luciliae
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c. Gamma globulin-coated particle
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d. Rh positive erythrocytes - CORRECT ANSWERS ✔✔c
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Positive rheumatoid factor is generally associated with:
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a. Anemia
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,b. Hyperglobulinemia
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c. Azotemia
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d. Decreased ESR - CORRECT ANSWERS ✔✔b
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Rheumatoid factors are defined as: |\ |\ |\ |\




a. Antigens found in patients with RA
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b. Autoantibodies with specificity for the Fc portion of the
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immunoglobulin (IgG) molecule |\ |\




c. Antibodies that bind to circulating IgM antibodies
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d. Are identical to the rheumatoid arthritis precipitin - CORRECT
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ANSWERS ✔✔b |\




High titers of antimicrosomal antibodies are most often found in :
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a. Rheumatoid arthritis
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b. SLE|\




c. Hepatitis
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d. Thyroid disease - CORRECT ANSWERS ✔✔d
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If an acute serum titer was 1:4 and the convalescent titer was
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1:32, what is the best interpretation?
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a. The test should be repeated
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b. The results are inconclusive since the titer went up instead of
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down
c. The patient had a previous infection
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d. The patient has an active infection - CORRECT ANSWERS ✔✔d
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, What is the labeled antibody in the indirect immunofluorescence
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method of antibody detection?
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a. Complement
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b. Anti-human immunoglobulin
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c. Rheumatoid factor
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d. Human anti-goat immunoglobulin - CORRECT ANSWERS ✔✔d
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A substrate is first exposed to a patient's serum, then after
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washing, anti-human immunoglobulin labeled with a
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fluorochrome is added. What is this procedure called? |\ |\ |\ |\ |\ |\ |\




a. Fluorescence inhibition
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b. Direct fluorescence
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c. Indirect fluorescence
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d. Fluorescent quenching - CORRECT ANSWERS ✔✔c
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What is Avidity?|\ |\




a. Degree of hemolysis
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b. Titer of an antigen
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c. Dilution of an antibody
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d. Strength of a reacting antibody - CORRECT ANSWERS ✔✔d
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What is the visible serological reaction between soluble antigen
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and its specific antibody called?
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a. Opsonization
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