NAPLEX Infectious Disease EXAM 2025/2026 Actual Complete Real Exam
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which aminopenicillin covers ampicillin - it is the drug of choice for listeria infections
listeria?
all B-lactams can decrease imipenem/cilastatin
seizure threshold, but which
B-lactam combo drug,
specifically, is thought to
cause seizures?
does augmentin cover no, amox/clav does not cover pseudomonas
pseudomonas?
which b-lactamase inhibitor Timentin (ticarcillin/clavulanic acid)
PCN combo can cause
thrombocytopenia and also
has 4x more Na_ than
other b-lactamase
inhibitors (concern for fluid
restricted pts)
of the three commercially Unasyn (ampicillin/sulbactam)
available IV PCN/B-
lactamase inhibitors,
which does not cover
pseudomonas?
what PCN/B-lact-inhib is unasyn (amp/sul)
good for surgery and bites?
Which PCN/B-lact-inhib has Zosyn (pip/tazo)
broad spectrum and may
be best for pseudomonas?
carbapenems are ertapenem (Invanz)
antipseudomonal except for
___?
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, 9/17/25, 9:53 AM NAPLEX Infectious Disease
T/F most Carbapanems F, none cover MRSA or VRE. (most, except ertapenem, cover
cover pseudomonas and pseudomonas)
MRSA, but none cover VRE.
Are carabapenems yes
effective against
anaerobes?
why is cilastatin added to to decrease nephrotoxicity of imipenem
iminpenem?
name the monobactam drug Aztreonam (Cayston, Azactam)
narrow spectrum gram - coverage.
describe, in general, (Citrobacter spp, Enterobacter spp, E. coli, H.
Aztreonam's coverage influenzae, Klebsiella oxytoca, K. pneumoniae, Proteus
mirabilis, Pseudomonas, Serratia marcescens)
does Azactam cover yes
pseudomonas?
what major organism do enterococcus
cephalosporins NOT cover?
in general, higher more
generations of
cephalosporins tend to have
- more or less? - beta
lactamase resistance?
in general, higher better gram - but worse gram +
generations of
cephalosporins tend to
have (better or worse?)
gram - coverage, and
(better or worse?) gram +
coverage?
What gram - bacteria do 1st P Ec K (proteus, E coli, Klebsiella)
generation cephs cover?
what gram - bacteria do H E N P Ec K (H flu, Enterobacter, Neisseria, proteus, E coli,
2nd generation cephs Klebsiella)
cover? which drugs cover
anaerobes - ceFOXitin, ceFOTetan
anaerobes?
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