Maryville University Pharmacology NURS-615 Exam 2
Questions and Answers with 100% Complete Solutions
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How does carbamazepine work? - ANSWER Works by
decreasing nerve impulses that cause seizures and pain
How often should carbamazepine lab values be monitored?
What labs? - ANSWER CBC q 3-4 months
What anti-seizure med auto induces metabolism? - ANSWER
Carbamazepine
What medication decreases the production of RBCs, WBCs, and
platelets? - ANSWER Carbamazepine
What is carbamazepine half-life? - ANSWER Single dose: 30
hours
Multiple dose: 15 hours
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What is a great risk of seizure potential while taking anti-seizure
medications? - ANSWER Stopping the medication abruptly.
What type of medication is topiramate (Topamax)? - ANSWER
Anti-seizure med
What does topiramate cause? - ANSWER Electrolyte imbalance -
- hyperchloremic metabolic acidosis
What are adverse effects of topiramate? - ANSWER Weight loss,
high temperature, and inability to sweat
What medication affects Lamictal? - ANSWER OCPs decrease
the effects of this drug, so the dose must be doubled
Can valproate (Depakote) be used during pregnancy? - ANSWER
It is a known teratogen. If needed, must be used after 1st
trimester.
What must be ruled out in patients before starting an anti-
depressant? - ANSWER hypothyroidism
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Anti-depressant that is to be used with caution in cardiac
patients due to behaving like class 1 anti-arrythmics? - ANSWER
TCAs
TCA side effects are mainly of what type? - ANSWER Anti-
cholinergic
What is a first-line antidepressant in children? - ANSWER
fluoxetine (Prozac)
How do you discontinue an SSRI? - ANSWER Taper by reducing
the dose by 50% for 3-4 days
When are MAOIs effective? - ANSWER In atypical depression or
Parkinson's
Why are MAOIs reserved for last line of treatment? - ANSWER
Lethal drug interactions and food interactions
How long before starting a new antidepressant after MAOIs? -
ANSWER At least 2 weeks to clear it from system