NR293/NR293 Pharmacology for Nursing
Final Exam| 200+Actual Questions and
Answers Latest Updated (Graded A+)-
Chamberlain
The nurse is discussing adverse effects of antitubercular drugs with a patient
who has active tuberculosis. Which potential adverse effect of antitubercular
drug therapy should the patient report to the prescriber?
a. Gastrointestinal upset
b. Headache and nervousness
c. Reddish-orange urine and stool
d. Numbness and tingling of extremities - Correct Answer: D
Patients on antitubercular therapy should report experiencing numbness and
tingling of extremities, which may indicate peripheral neuropathy. Some drugs
may color the urine, stool, and other body secretions reddish-orange, but this
is not an effect that needs to be reported. Patients need to be informed of this
expected effect.
A patient who has been taking isoniazid (INH) has a new prescription for
pyridoxine. She is wondering why she needs this medication. The nurse
explains that pyridoxine is often given concurrently with the isoniazid to
prevent which condition?
a. Hair loss
b. Renal failure
c. Peripheral neuropathy
d. Heart failure - Correct Answer: C
,Pyridoxine (vitamin B6) may be beneficial for isoniazid-induced peripheral
neuropathy. The other options are incorrect.
The nurse will assess the patient for which potential contraindication to
antitubercular therapy?
a. Glaucoma
b. Anemia
c. Heart failure
d. Hepatic impairment - Correct Answer: D
Results of liver function studies (e.g., bilirubin level, liver enzyme levels) need
to be assessed because isoniazid and rifampin may cause hepatic impairment;
severe liver dysfunction is a contraindication to these drugs. In addition, the
patient's history of alcohol use needs to be assessed.
When monitoring patients on antitubercular drug therapy, the nurse knows
that which drug may cause a decrease in visual acuity?
a. Rifampin (Rifadin)
b. Isoniazid (INH)
c. Ethambutol (Myambutol)
d. Streptomycin - Correct Answer: C
Ethambutol may cause a decrease in visual acuity or even blindness resulting
from retrobulbar neuritis. The other options are incorrect.
A patient has been taking antitubercular therapy for 3 months. The nurse will
assess for what findings that indicate a therapeutic response to the drug
therapy?
a. The chronic cough is gone.
b. There are two consecutive negative purified protein derivative (PPD) results
over 2 months.
c. There is increased tolerance to the medication therapy, and there are fewer
reports of adverse effects.
,d. There is a decrease in symptoms of tuberculosis along with improved chest
x-rays and sputum cultures. - Correct Answer: D
A therapeutic response to antitubercular therapy is manifested by a decrease in
the symptoms of tuberculosis, such as cough and fever, and by weight gain.
The results of laboratory studies (culture and sensitivity tests) and the chest
radiographic findings will be used to confirm the clinical findings of resolution
of the infection.
The nurse is counseling a woman who will be starting rifampin (Rifadin) as
part of antitubercular therapy. The patient is currently taking oral
contraceptives. Which statement is true regarding rifampin therapy for this
patient?
a. Women have a high risk for thrombophlebitis while on this drug.
b. A higher dose of rifampin will be necessary because of the contraceptive.
c. Oral contraceptives are less effective while the patient is taking rifampin.
d. The incidence of adverse effects is greater if the two drugs are taken
together. x - Correct Answer: C
Women taking oral contraceptives and rifampin need to be counseled about
other forms of birth control because of the impaired effectiveness of the oral
contraceptives during concurrent use of rifampin.
A patient newly diagnosed with tuberculosis (TB) has been taking
antitubercular drugs for 1 week calls the clinic and is very upset. He says, "My
urine is dark orange! What's wrong with me?" Which response by the nurse is
correct?
a. "You will need to stop the medication, and it will go away."
b. "It's possible that the TB is worse. Please come in to the clinic to be
checked."
c. "This is not what we usually see with these drugs. Please come in to the
clinic to be checked."
d. "This is an expected side effect of the medicine. Let's review what to
expect." - Correct Answer: D
, Rifampin, one of the first-line drugs for TB, causes a red-orange-brown
discoloration of urine, tears, sweat, and sputum. Patients need to be warned
about this side effect. The other options are incorrect.
The nurse is reviewing the medication administration record of a patient who
is taking isoniazid (INH). Which drug or drug class has a significant drug
interaction with isoniazid?
a. Pyridoxine (vitamin B6)
b. Penicillins
c. Phenytoin (Dilantin)
d. Benzodiazepines - Correct Answer: C
Taking INH with phenytoin will cause decreased metabolism of the
phenytoin, leading to increased drug effects. Pyridoxine is often given with
isoniazid to prevent peripheral neuropathy. The other options are incorrect.
PPD (purified protein derivative) - ==>•A diagnostic injection given
intradermally in doses of 5 tuberculin units (0.1 mL) to detect exposure to the
TB organism
•Positive result is indicated by induration (not erythema) at the site of injection
BCG (Bacille Calmette-Guérin) - ==>•A vaccine injection derived from an
inactivated strain of Mycobacterium bovis
•Can cause false-positive results on the tuberculin skin test
A patient who has started drug therapy for tuberculosis wants to know how
long he will be on the medications. Which response by the nurse is correct?
a. "Drug therapy will last until the symptoms have stopped."
b. "Drug therapy will continue until the tuberculosis develops resistance."
c. "You should expect to take these drugs for as long as 24 months."
d. "You will be on this drug therapy for the rest of your life." - Correct Answer:
C
Drug therapy commonly lasts for 24 months if consistent drug therapy has
been maintained.
Final Exam| 200+Actual Questions and
Answers Latest Updated (Graded A+)-
Chamberlain
The nurse is discussing adverse effects of antitubercular drugs with a patient
who has active tuberculosis. Which potential adverse effect of antitubercular
drug therapy should the patient report to the prescriber?
a. Gastrointestinal upset
b. Headache and nervousness
c. Reddish-orange urine and stool
d. Numbness and tingling of extremities - Correct Answer: D
Patients on antitubercular therapy should report experiencing numbness and
tingling of extremities, which may indicate peripheral neuropathy. Some drugs
may color the urine, stool, and other body secretions reddish-orange, but this
is not an effect that needs to be reported. Patients need to be informed of this
expected effect.
A patient who has been taking isoniazid (INH) has a new prescription for
pyridoxine. She is wondering why she needs this medication. The nurse
explains that pyridoxine is often given concurrently with the isoniazid to
prevent which condition?
a. Hair loss
b. Renal failure
c. Peripheral neuropathy
d. Heart failure - Correct Answer: C
,Pyridoxine (vitamin B6) may be beneficial for isoniazid-induced peripheral
neuropathy. The other options are incorrect.
The nurse will assess the patient for which potential contraindication to
antitubercular therapy?
a. Glaucoma
b. Anemia
c. Heart failure
d. Hepatic impairment - Correct Answer: D
Results of liver function studies (e.g., bilirubin level, liver enzyme levels) need
to be assessed because isoniazid and rifampin may cause hepatic impairment;
severe liver dysfunction is a contraindication to these drugs. In addition, the
patient's history of alcohol use needs to be assessed.
When monitoring patients on antitubercular drug therapy, the nurse knows
that which drug may cause a decrease in visual acuity?
a. Rifampin (Rifadin)
b. Isoniazid (INH)
c. Ethambutol (Myambutol)
d. Streptomycin - Correct Answer: C
Ethambutol may cause a decrease in visual acuity or even blindness resulting
from retrobulbar neuritis. The other options are incorrect.
A patient has been taking antitubercular therapy for 3 months. The nurse will
assess for what findings that indicate a therapeutic response to the drug
therapy?
a. The chronic cough is gone.
b. There are two consecutive negative purified protein derivative (PPD) results
over 2 months.
c. There is increased tolerance to the medication therapy, and there are fewer
reports of adverse effects.
,d. There is a decrease in symptoms of tuberculosis along with improved chest
x-rays and sputum cultures. - Correct Answer: D
A therapeutic response to antitubercular therapy is manifested by a decrease in
the symptoms of tuberculosis, such as cough and fever, and by weight gain.
The results of laboratory studies (culture and sensitivity tests) and the chest
radiographic findings will be used to confirm the clinical findings of resolution
of the infection.
The nurse is counseling a woman who will be starting rifampin (Rifadin) as
part of antitubercular therapy. The patient is currently taking oral
contraceptives. Which statement is true regarding rifampin therapy for this
patient?
a. Women have a high risk for thrombophlebitis while on this drug.
b. A higher dose of rifampin will be necessary because of the contraceptive.
c. Oral contraceptives are less effective while the patient is taking rifampin.
d. The incidence of adverse effects is greater if the two drugs are taken
together. x - Correct Answer: C
Women taking oral contraceptives and rifampin need to be counseled about
other forms of birth control because of the impaired effectiveness of the oral
contraceptives during concurrent use of rifampin.
A patient newly diagnosed with tuberculosis (TB) has been taking
antitubercular drugs for 1 week calls the clinic and is very upset. He says, "My
urine is dark orange! What's wrong with me?" Which response by the nurse is
correct?
a. "You will need to stop the medication, and it will go away."
b. "It's possible that the TB is worse. Please come in to the clinic to be
checked."
c. "This is not what we usually see with these drugs. Please come in to the
clinic to be checked."
d. "This is an expected side effect of the medicine. Let's review what to
expect." - Correct Answer: D
, Rifampin, one of the first-line drugs for TB, causes a red-orange-brown
discoloration of urine, tears, sweat, and sputum. Patients need to be warned
about this side effect. The other options are incorrect.
The nurse is reviewing the medication administration record of a patient who
is taking isoniazid (INH). Which drug or drug class has a significant drug
interaction with isoniazid?
a. Pyridoxine (vitamin B6)
b. Penicillins
c. Phenytoin (Dilantin)
d. Benzodiazepines - Correct Answer: C
Taking INH with phenytoin will cause decreased metabolism of the
phenytoin, leading to increased drug effects. Pyridoxine is often given with
isoniazid to prevent peripheral neuropathy. The other options are incorrect.
PPD (purified protein derivative) - ==>•A diagnostic injection given
intradermally in doses of 5 tuberculin units (0.1 mL) to detect exposure to the
TB organism
•Positive result is indicated by induration (not erythema) at the site of injection
BCG (Bacille Calmette-Guérin) - ==>•A vaccine injection derived from an
inactivated strain of Mycobacterium bovis
•Can cause false-positive results on the tuberculin skin test
A patient who has started drug therapy for tuberculosis wants to know how
long he will be on the medications. Which response by the nurse is correct?
a. "Drug therapy will last until the symptoms have stopped."
b. "Drug therapy will continue until the tuberculosis develops resistance."
c. "You should expect to take these drugs for as long as 24 months."
d. "You will be on this drug therapy for the rest of your life." - Correct Answer:
C
Drug therapy commonly lasts for 24 months if consistent drug therapy has
been maintained.
