Maryville University: NURS615 Pharm Exam 1 UPDATED
ACTUAL Questions and CORRECT Answers
1. Clinical Judgement Conclusion/opinion at which a nurse arrives following a process of observation,
reflection, & analysis of observable or available information or data.
*must gather data to make diagnosis, must have diagnosis to select and start
treatment
2. WHO 6-Step Mod- 1. Define patient's problem (diagnose)
el of Rational Pre- 2. Specify the therapeutic objective (goal)
scribing 3. Choose treatment
4. Start treatment
5. Educate the patient
6. Monitor the effectiveness
3. Criteria for choos- I=indication
ing an effective C=contraindication
drug P=precautions
"I Can PresCribe A C=cost/compliance
Drug" Mnemonic E=eflcacy
A=adverse effects
D=dose/duration/direction
4. Role of FDA Ensures the safety, eflcacy, and security of human and veterinary drugs, bio-
logical products, and medical devices. As well as food, cosmetics, and products
that emit radiation.
5. What is the role Does NOT protect or ensure the safety of supplements and vitamins. They have
of the FDA in re- certain rules, but they aren't as stringent like they are for drugs.
gard to supple-
ments and vita-
mins?
6. What can St. John's SSRI, CNS drugs, MAOI, SSNRI, steroids, caffeine, and anticoagulants.
wort interact with?
, Maryville University: NURS615 Pharm Exam 1 UPDATED
ACTUAL Questions and CORRECT Answers
7. Off-label prescrib- medication is being used in a manner not specified in the FDAs approved
ing packaging label/insert.
*different route, dose, or indication
8. Pharmacothera- study of therapeutic uses and effects of drugs. Beneficial and adverse drug
peutics reactions.
9. Pharmacodynam- what the drug does to the body
ics
10. Agonist binds to a receptor & produces a response/stimulates (full activation)
11. Antagonist Binds & blocks activity (no activation)
12. Can a drug be an Yes. In this case, they do both actions to have less activation, versus full or no
agonist and antag- activation.
onist?
13. Pharmacokinetics what the body does to the drug (ADME)
14. What is ADME in absorption, distribution, metabolism, excretion
pharmacokinetics?
15. Absorption first step, occurs after medication administration
16. What does absorp- routes of administration, pH and membrane penetration
tion depend on?
17. What percentage 50%
of rectal drugs go
through first-pass
metabolism?
18. lipid solubility and ionization
, Maryville University: NURS615 Pharm Exam 1 UPDATED
ACTUAL Questions and CORRECT Answers
Membrane pen-
etration involves
what?
19. How does pH af- If the pH of the stomach is altered, in oral medication administration, the
fect absorption? medication can be absorbed too soon or not soon enough.
20. Why can't you This interferes with absorption, it will not absorb where intended.
crush enteric coat-
ed medications?
21. Ionization the charge of the molecule/drug.
Ionized = charged (polar)
non-ionized = uncharged (non-polar)
22. Lipophilic *Lipid loving, uncharged (non-polar/non-ionized), small in size.
*crosses membranes more easily than hydrophilic
23. How do lipophilic Passive diffusion. Most cell membranes are lipophilic, making it easier for
drugs cross mem- lipophilic drugs to cross.
branes?
24. Passive diffusion the movement of drugs from an area of higher concentration to lower concen-
tration (moves across a concentration gradient)
25. What is the volume Lipophilic drugs have a high volume of distribution and a long duration of
of distribution for action.
lipophilic drugs?
26. Hydrophilic *Water loving, charged (ionized/polar), large in size
*more diflcultly with crossing membranes
27. Active transport or filtration
ACTUAL Questions and CORRECT Answers
1. Clinical Judgement Conclusion/opinion at which a nurse arrives following a process of observation,
reflection, & analysis of observable or available information or data.
*must gather data to make diagnosis, must have diagnosis to select and start
treatment
2. WHO 6-Step Mod- 1. Define patient's problem (diagnose)
el of Rational Pre- 2. Specify the therapeutic objective (goal)
scribing 3. Choose treatment
4. Start treatment
5. Educate the patient
6. Monitor the effectiveness
3. Criteria for choos- I=indication
ing an effective C=contraindication
drug P=precautions
"I Can PresCribe A C=cost/compliance
Drug" Mnemonic E=eflcacy
A=adverse effects
D=dose/duration/direction
4. Role of FDA Ensures the safety, eflcacy, and security of human and veterinary drugs, bio-
logical products, and medical devices. As well as food, cosmetics, and products
that emit radiation.
5. What is the role Does NOT protect or ensure the safety of supplements and vitamins. They have
of the FDA in re- certain rules, but they aren't as stringent like they are for drugs.
gard to supple-
ments and vita-
mins?
6. What can St. John's SSRI, CNS drugs, MAOI, SSNRI, steroids, caffeine, and anticoagulants.
wort interact with?
, Maryville University: NURS615 Pharm Exam 1 UPDATED
ACTUAL Questions and CORRECT Answers
7. Off-label prescrib- medication is being used in a manner not specified in the FDAs approved
ing packaging label/insert.
*different route, dose, or indication
8. Pharmacothera- study of therapeutic uses and effects of drugs. Beneficial and adverse drug
peutics reactions.
9. Pharmacodynam- what the drug does to the body
ics
10. Agonist binds to a receptor & produces a response/stimulates (full activation)
11. Antagonist Binds & blocks activity (no activation)
12. Can a drug be an Yes. In this case, they do both actions to have less activation, versus full or no
agonist and antag- activation.
onist?
13. Pharmacokinetics what the body does to the drug (ADME)
14. What is ADME in absorption, distribution, metabolism, excretion
pharmacokinetics?
15. Absorption first step, occurs after medication administration
16. What does absorp- routes of administration, pH and membrane penetration
tion depend on?
17. What percentage 50%
of rectal drugs go
through first-pass
metabolism?
18. lipid solubility and ionization
, Maryville University: NURS615 Pharm Exam 1 UPDATED
ACTUAL Questions and CORRECT Answers
Membrane pen-
etration involves
what?
19. How does pH af- If the pH of the stomach is altered, in oral medication administration, the
fect absorption? medication can be absorbed too soon or not soon enough.
20. Why can't you This interferes with absorption, it will not absorb where intended.
crush enteric coat-
ed medications?
21. Ionization the charge of the molecule/drug.
Ionized = charged (polar)
non-ionized = uncharged (non-polar)
22. Lipophilic *Lipid loving, uncharged (non-polar/non-ionized), small in size.
*crosses membranes more easily than hydrophilic
23. How do lipophilic Passive diffusion. Most cell membranes are lipophilic, making it easier for
drugs cross mem- lipophilic drugs to cross.
branes?
24. Passive diffusion the movement of drugs from an area of higher concentration to lower concen-
tration (moves across a concentration gradient)
25. What is the volume Lipophilic drugs have a high volume of distribution and a long duration of
of distribution for action.
lipophilic drugs?
26. Hydrophilic *Water loving, charged (ionized/polar), large in size
*more diflcultly with crossing membranes
27. Active transport or filtration
