Page 1 of 25
Pharmacology HESI Practice Exam 2 2025Review Questions PRACTICE GRADED A+
QUESTIONS WITH CORRECT ANSWERS GRADED A+ 2025-2026 VERIFIED
Which instructions should the nurse give to a femail client who just recieved a
prescription for oral metronidazole (flagyl) for treatment of trichomonas
vaginalis (select all that apply)
A. increase fluid intake, especially cranberry juice
B. Do not abruptly discontinue the medication; taper use
C. Check blood pressure daily to detect hypertension
D. Avoid drinking alcohol while taking this medication
E. Use condoms until treatment is completed
F. Ensure that all sexual partners are treated at the same time
A, D, E, F
A client is taking hydromorphone (Dilaudid) PO q4h at home. Following
surgery, Dilaudid IV q4h PRN and butorphanol tartrate (Stadol) IV q4h PRN are
prescribed for pain. The client received a dose of the Dilaudid IV four hours
ago, and is again requesting pain medication. What intervention should the
nurse implement?
A) Alternate the two medications q4h PRN for pain.
B) Alternate the two medications q2h PRN for pain.
C) Administer only the Dilaudid q4h PRN for pain.
D) Administer only the Stadol q4h PRN for pain.
C. Administer only the Dilaudid q4h PRN for pain.
Dilaudid is an opioid agonist. Stadol is an opioid agonist-antagonist. Use of an
agonist-antagonist for the client who has been receiving opioid agonists may result in
abrupt withdrawal symptoms, and should be avoided (C). (A, B, and D) do not reflect
good nursing practice.
Which nursing diagnosis is important to include in the plan of care for a client
recieving the angiotensin II receptor antagonist irbesartan (avapro)?
A. Fluid volume deficit
B.Risk for infection
C. Risk for injury
D. Impaired sleep patterns
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C. Risk for injury
Avapro is an antihypertensive agent, which acts by blocking vasoconstrictor effects
at various receptor sites. This can cause hypotension and dizziness, placing the
client at high risk for injury
A client is being treated for osteoporosis with alendronate (fosamax), and the
nurse has completed discharge teaching regarding medication administration.
Which morning schedule would indicated to the nurse that the client teaching
has been effective?
A. take medication, go for a30 minutes morning walk, then eat breakfast
B. take med, rest in bed for 30 min., eat breakfast, go for morning walk
C. take medication with breakfast, then take a 30 minute morning walk
D. go for a 30minute morning walk, eat breakfast, then take the med
A. take medication, go for a30 minutes morning walk, then eat breakfast
A client is admitted to the hospital for diagnostic testing for possible
myasthenia gravis. The nurse prepares for intravenous administration of
edrophonium chloride (Tensilon). What is the expected outcome for this client
following administration of this pharmacologic agent?
A) Progressive difficulty with swallowing.
B) Decreased respiratory effort.
C) Improvement in generalized fatigue.
D) Decreased muscle weakness.
D) Decreased muscle weakness.
Administration of edrophonium chloride (Tensilon), a cholinergic agent, will
temporarily reduce muscle weakness (D), the most common complaint of newly-
diagnosed clients with myasthenia gravis. This medication is used to diagnose
myasthenia gravis due to its short duration of action. This drug would temporarily
reverse (A and B), not increase these symptoms. (C) is not a typical complaint of
clients with myasthenia gravis, but weakness of specific muscles, especially after
prolonged use, is a common symptom.
When assessing an adolescent who recently overdosed on acetaminophen
(tylonel), it is most important for the nurse to assess for pain in which area of
the body
a. flank
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b. abdomen
c. chest
d. head
B. acetaminophen toxicisty an result in liver damage; therefore, it is especially
important for the nurse to assess for pain in the right upper quadrant of the abdomen
(which might indicated liver damage)
which symptoms are serious adverse effects of beta-adrenergic blockers such
as propranolol (inderal)?
A. Headache, hypertension, and blurred vision.
B. Wheezing, hypotension, and AV block.
C. Vomiting, dilated pupils, and papilledema.
D. Tinnitus, muscle weakness, and tachypnea.
B. Wheezing, hypotension, and AV block.
(B) represents the most serious adverse effects of beta-blocking agents. AV block is
generally associated with bradycardia and results in potentially life-threatening
decreases in cardiac output. Additionally, wheezing secondary to bronchospasm and
hypotension represent life-threatening respiratory and cardiac disorders. (A, C, and
D) are not associated with beta-blockers.
The healthcare provider prescribes naloxone (Narcan) for a client in the
emergency room. Which assessment data would indicate that the naloxone
has been effective? The client's...
A. Statement that the chest pain is better
B) respiratory rate is 16 breaths/minute.
C) seizure activity has stopped temporarily.
D) pupils are constricted bilaterally.
B.
Naloxone (Narcan) is a narcotic antagonist that reverses the respiratory depression
effects of opiate overdose, so assessment of a normal respiratory rate (B) would
indicate that the respiratory depression has been halted. (A, C, and D) are not
related to naloxone (Narcan) administration.
A client has myxedema, which results from a deficiency of thyroid hormone
synthesis in adults. The nurse knows that which medication should be
contraindicated for this client?
A. liothyronine (cytomel) to replace iodine
Pharmacology HESI Practice Exam 2 2025Review Questions PRACTICE GRADED A+
QUESTIONS WITH CORRECT ANSWERS GRADED A+ 2025-2026 VERIFIED
Which instructions should the nurse give to a femail client who just recieved a
prescription for oral metronidazole (flagyl) for treatment of trichomonas
vaginalis (select all that apply)
A. increase fluid intake, especially cranberry juice
B. Do not abruptly discontinue the medication; taper use
C. Check blood pressure daily to detect hypertension
D. Avoid drinking alcohol while taking this medication
E. Use condoms until treatment is completed
F. Ensure that all sexual partners are treated at the same time
A, D, E, F
A client is taking hydromorphone (Dilaudid) PO q4h at home. Following
surgery, Dilaudid IV q4h PRN and butorphanol tartrate (Stadol) IV q4h PRN are
prescribed for pain. The client received a dose of the Dilaudid IV four hours
ago, and is again requesting pain medication. What intervention should the
nurse implement?
A) Alternate the two medications q4h PRN for pain.
B) Alternate the two medications q2h PRN for pain.
C) Administer only the Dilaudid q4h PRN for pain.
D) Administer only the Stadol q4h PRN for pain.
C. Administer only the Dilaudid q4h PRN for pain.
Dilaudid is an opioid agonist. Stadol is an opioid agonist-antagonist. Use of an
agonist-antagonist for the client who has been receiving opioid agonists may result in
abrupt withdrawal symptoms, and should be avoided (C). (A, B, and D) do not reflect
good nursing practice.
Which nursing diagnosis is important to include in the plan of care for a client
recieving the angiotensin II receptor antagonist irbesartan (avapro)?
A. Fluid volume deficit
B.Risk for infection
C. Risk for injury
D. Impaired sleep patterns
, Page 2 of 25
C. Risk for injury
Avapro is an antihypertensive agent, which acts by blocking vasoconstrictor effects
at various receptor sites. This can cause hypotension and dizziness, placing the
client at high risk for injury
A client is being treated for osteoporosis with alendronate (fosamax), and the
nurse has completed discharge teaching regarding medication administration.
Which morning schedule would indicated to the nurse that the client teaching
has been effective?
A. take medication, go for a30 minutes morning walk, then eat breakfast
B. take med, rest in bed for 30 min., eat breakfast, go for morning walk
C. take medication with breakfast, then take a 30 minute morning walk
D. go for a 30minute morning walk, eat breakfast, then take the med
A. take medication, go for a30 minutes morning walk, then eat breakfast
A client is admitted to the hospital for diagnostic testing for possible
myasthenia gravis. The nurse prepares for intravenous administration of
edrophonium chloride (Tensilon). What is the expected outcome for this client
following administration of this pharmacologic agent?
A) Progressive difficulty with swallowing.
B) Decreased respiratory effort.
C) Improvement in generalized fatigue.
D) Decreased muscle weakness.
D) Decreased muscle weakness.
Administration of edrophonium chloride (Tensilon), a cholinergic agent, will
temporarily reduce muscle weakness (D), the most common complaint of newly-
diagnosed clients with myasthenia gravis. This medication is used to diagnose
myasthenia gravis due to its short duration of action. This drug would temporarily
reverse (A and B), not increase these symptoms. (C) is not a typical complaint of
clients with myasthenia gravis, but weakness of specific muscles, especially after
prolonged use, is a common symptom.
When assessing an adolescent who recently overdosed on acetaminophen
(tylonel), it is most important for the nurse to assess for pain in which area of
the body
a. flank
, Page 3 of 25
b. abdomen
c. chest
d. head
B. acetaminophen toxicisty an result in liver damage; therefore, it is especially
important for the nurse to assess for pain in the right upper quadrant of the abdomen
(which might indicated liver damage)
which symptoms are serious adverse effects of beta-adrenergic blockers such
as propranolol (inderal)?
A. Headache, hypertension, and blurred vision.
B. Wheezing, hypotension, and AV block.
C. Vomiting, dilated pupils, and papilledema.
D. Tinnitus, muscle weakness, and tachypnea.
B. Wheezing, hypotension, and AV block.
(B) represents the most serious adverse effects of beta-blocking agents. AV block is
generally associated with bradycardia and results in potentially life-threatening
decreases in cardiac output. Additionally, wheezing secondary to bronchospasm and
hypotension represent life-threatening respiratory and cardiac disorders. (A, C, and
D) are not associated with beta-blockers.
The healthcare provider prescribes naloxone (Narcan) for a client in the
emergency room. Which assessment data would indicate that the naloxone
has been effective? The client's...
A. Statement that the chest pain is better
B) respiratory rate is 16 breaths/minute.
C) seizure activity has stopped temporarily.
D) pupils are constricted bilaterally.
B.
Naloxone (Narcan) is a narcotic antagonist that reverses the respiratory depression
effects of opiate overdose, so assessment of a normal respiratory rate (B) would
indicate that the respiratory depression has been halted. (A, C, and D) are not
related to naloxone (Narcan) administration.
A client has myxedema, which results from a deficiency of thyroid hormone
synthesis in adults. The nurse knows that which medication should be
contraindicated for this client?
A. liothyronine (cytomel) to replace iodine
