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Lehninger Principles of Biochemistry Seventh Edition – Complete Test Bank with Answer Key

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This comprehensive test bank accompanies Lehninger Principles of Biochemistry, Seventh Edition by Nelson and Cox. It includes hundreds of multiple-choice questions covering all major topics in biochemistry, from foundational concepts like cell structure, water chemistry, and amino acids, to advanced topics such as enzyme kinetics, nucleic acids, carbohydrate and lipid metabolism, membrane structure, and molecular biology techniques. Each question is designed to test understanding and application of key principles, making this an ideal resource for students preparing for exams, instructors creating assessments, or anyone seeking to review core biochemistry content. The questions are organized by chapter and difficulty, reflecting the structure and rigor of the leading textbook in the field.

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Institution
Lehninger
Course
Lehninger

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,1. In a bacterial cell, the DNA is in the:
z z z z z z z z



A) cell envelope. z



B) cell membrane. z



C) nucleoid.
D) nucleus.
E) ribosomes.


2. A major change occurring in the evolution of eukaryotes from prokaryotes was the
z z z z z z z z z z z z



development of: z



A) DNA.
B) photosynthetic capability. z



C) plasma membranes. z



D) ribosomes.
E) the nucleus. z




3. In eukaryotes, the nucleus is enclosed by a double membrane called the:
z z z z z z z z z z z



A) cell membrane. z



B) nuclear envelope. z



C) nucleolus.
D) nucleoplasm.
E) nucleosome.


4. The dimensions of living cells are limited, on the lower end by the minimum number of
z z z z z z z z z z z z z z z



biomolecules necessary for function, and on the upper end by the rate of diffusion of
z z z z z z z z z z z z z z z



solutes such as oxygen. Except for highly elongated cells, they usually have lengths and
z z z z z z z z z z z z z z



diameters in the range of:
z z z z z



A) 0.1 m to 10 m. z z z z



B) 0.3 m to 30 m. z z z z



C) 0.3 m to 100 m. z z z z



D) 1 m to 100 m.
z z z z



E) 1 m to 300 m.
z z z z




5. Which group of single-celled microorganisms has many members found growing in
z z z z z z z z z z



extreme environments? z



A) bacteria
B) archaea
C) eukaryotes
D) heterotrophs
E) None of the answers is correct. z z z z z




Page 1

, 6. The bacterium E. coli requires simple organic molecules for growth and energyóit is
z z z z z z z z z z z z



therefore a: z



A) chemoautotroph.
B) chemoheterotroph.
C) lithotroph.
D) photoautotroph.
E) photoheterotroph.


7. Which is a list of organelles?
z z z z z



A) mitochondria, chromatin, endoplasmic reticulum z z z



B) peroxisomes, lysosomes, plasma membrane z z z



C) proteasomes, peroxisomes, lysosomes z z



D) mitochondria, endoplasmic reticulum, peroxisomes z z z



E) All of the answers are correct.
z z z z z




8. Which list has the cellular components arranged in order of INCREASING size?
z z z z z z z z z z z



A) amino acid < protein < mitochondrion < ribosome
z z z z z z z



B) amino acid < protein < ribosome < mitochondrion
z z z z z z z



C) amino acid < ribosome < protein < mitochondrion
z z z z z z z



D) protein < amino acid < mitochondrion < ribosome
z z z z z z z



E) protein < ribosome < mitochondrion < amino acid
z z z z z z z




9. The three-dimensional structure of macromolecules is formed and maintained primarily
z z z z z z z z z



through noncovalent interactions. Which one of the following is NOT considered a
z z z z z z z z z z z z



noncovalent interaction? z



A) carbon-carbon bonds z



B) hydrogen bonds z



C) hydrophobic interactions z



D) ionic interactions z



E) van der Waals interactions
z z z




10. Which element is NOT among the four most abundant in living organisms?
z z z z z z z z z z z



A) carbon
B) hydrogen
C) nitrogen
D) oxygen
E) phosphorus




Page 2

, 11. The four covalent bonds in methane (CH4) are arranged around carbon to give which
z z z z z z z z z z z z z



geometry?
z



A) linear
B) tetrahedral
C) trigonal bipyramidal z



D) trigonal planar z



E) trigonal pyramidal z




12. What functional groups are present on this molecule?
z z z z z z z




A) ether and aldehyde
z z



B) hydroxyl and aldehyde z z



C) hydroxyl and carboxylic acid
z z z



D) hydroxyl and ester z z



E) hydroxyl and ketone z z




13. The macromolecules that serve in the storage and transmission of genetic information
z z z z z z z z z z z



are:
A) carbohydrates.
B) lipids.
C) membranes.
D) nucleic acids. z



E) proteins.


14. Stereoisomers that are nonsuperimposable mirror images of each other are known as:
z z z z z z z z z z z



A) anomers.
B) cis-trans isomers. z



C) diastereoisomers.
D) enantiomers.
E) geometric isomers. z




Page 3

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