NEW NR 508 MIDTERM WEEK 4 PRACTICE
EXAM Q&A TESTED AND APPROVED NEWLY
MODIFIED!!!
The route of excretion of a volatile drug will likely be the:
1. Kidneys
2. Lungs
3. Bile and feces
4. Skin -- ANSWER--2 lungs
Depo Provera is prescribed intramuscularly to create a storage reservoir of the drug. Storage
reservoirs:
1. Assure that the drug will reach its intended target tissue
2. Are the reason for giving loading doses
3. Increase the length of time a drug is available and active
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,4. Are most common in collagen tissues -- ANSWER--3. Increase the length of time a
drug is available and active
The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's:
1. Propensity to go to the target receptor
2. Biological half-life
3. Pharmacodynamics
4. Safety and side effects -- ANSWER--2. Biological half-life
Azithromycin dosing requires that the first day's dosage be twice those of the other 4 days of
the prescription. This is considered a loading dose. A loading dose:
1. Rapidly achieves drug levels in the therapeutic range
2. Requires four or five half lives to attain
3. Is influenced by renal function
4. Is directly related to the drug circulating to the target tissues -- ANSWER--1. Rapidly
achieves drug levels in the therapeutic range
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,The point in time on the drug concentration curve that indicates the first sign of a
therapeutic effect is the:
1. Minimum adverse effect level
2. Peak of action
3. Onset of action
4. Therapeutic range -- ANSWER--3. Onset of action
A laboratory result indicates that the peak level for a drug is above the minimum toxic
concentration. This means that the:
1. Concentration will produce therapeutic effects
2. Concentration will produce an adverse response
3. Time between doses must be shortened
4. Duration of action of the drug is too long -- ANSWER--2. Concentration will produce
an adverse response
Drugs that are receptor agonists may demonstrate what property?
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, 1. Irreversible binding to the drug receptor site
2. Up-regulation with chronic use
3. Desensitization or down-regulation with continuous use
4. Inverse relationship between drug concentration and drug action -- ANSWER--3.
Desensitization or down-regulation with continuous use
Drugs that are receptor antagonists, such as beta blockers, may cause:
1. Down regulation of the drug receptor
2. And exaggerated response if abruptly discontinued
3. Partial blockade of the effects of agonist drugs
4. An exaggerated response to competitive drug agonsits -- ANSWER--2. An
exaggerated response if abruptly discontinued
Factors that affect gastric drug absorption include
1. Liver enzyme activity
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EXAM Q&A TESTED AND APPROVED NEWLY
MODIFIED!!!
The route of excretion of a volatile drug will likely be the:
1. Kidneys
2. Lungs
3. Bile and feces
4. Skin -- ANSWER--2 lungs
Depo Provera is prescribed intramuscularly to create a storage reservoir of the drug. Storage
reservoirs:
1. Assure that the drug will reach its intended target tissue
2. Are the reason for giving loading doses
3. Increase the length of time a drug is available and active
Page 1 of 247
,4. Are most common in collagen tissues -- ANSWER--3. Increase the length of time a
drug is available and active
The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's:
1. Propensity to go to the target receptor
2. Biological half-life
3. Pharmacodynamics
4. Safety and side effects -- ANSWER--2. Biological half-life
Azithromycin dosing requires that the first day's dosage be twice those of the other 4 days of
the prescription. This is considered a loading dose. A loading dose:
1. Rapidly achieves drug levels in the therapeutic range
2. Requires four or five half lives to attain
3. Is influenced by renal function
4. Is directly related to the drug circulating to the target tissues -- ANSWER--1. Rapidly
achieves drug levels in the therapeutic range
Page 2 of 247
,The point in time on the drug concentration curve that indicates the first sign of a
therapeutic effect is the:
1. Minimum adverse effect level
2. Peak of action
3. Onset of action
4. Therapeutic range -- ANSWER--3. Onset of action
A laboratory result indicates that the peak level for a drug is above the minimum toxic
concentration. This means that the:
1. Concentration will produce therapeutic effects
2. Concentration will produce an adverse response
3. Time between doses must be shortened
4. Duration of action of the drug is too long -- ANSWER--2. Concentration will produce
an adverse response
Drugs that are receptor agonists may demonstrate what property?
Page 3 of 247
, 1. Irreversible binding to the drug receptor site
2. Up-regulation with chronic use
3. Desensitization or down-regulation with continuous use
4. Inverse relationship between drug concentration and drug action -- ANSWER--3.
Desensitization or down-regulation with continuous use
Drugs that are receptor antagonists, such as beta blockers, may cause:
1. Down regulation of the drug receptor
2. And exaggerated response if abruptly discontinued
3. Partial blockade of the effects of agonist drugs
4. An exaggerated response to competitive drug agonsits -- ANSWER--2. An
exaggerated response if abruptly discontinued
Factors that affect gastric drug absorption include
1. Liver enzyme activity
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