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A patient presents with a complaint of dark stools and epigastric pain described as
gnawing and burning. Which of the medications is the most likely cause? - CORRECT
ANSWER: Bethanechol
Abrupt withdrawal of beta blockers can be life threatening. Patients at highest risk for
serious consequences of rapid withdrawal are those with: - CORRECT ANSWER:
Angina
Coronary artery disease
Activation of central alpha2 receptors results in inhibition of cardioacceleration and
______________ centers in the brain. - CORRECT ANSWER: Vasoconstriction
Adherence is improved when a drug can be given once daily. Which of the following
drugs can be given once daily? - CORRECT ANSWER: Donepezil
Adherence to beta blocker therapy may be affected by their: - CORRECT ANSWER:
Effects on the male genitalia, which may produce impotence
Alpha-beta blockers are especially effective to treat hypertension for which ethnic
group? - CORRECT ANSWER: African American
Anticholinesterase inhibitors are used to treat: - CORRECT ANSWER: Myasthenia
gravis
,Beta blockers are prescribed for diabetics with caution because of their ability to
produce hypoglycemia and block the common symptoms of it. Which of the following
symptoms of hypoglycemia is not blocked by these drugs and so can be used to warn
diabetics of possible decreased blood glucose? - CORRECT ANSWER: Diaphoresis
Beta blockers are the drugs of choice for exertional angina because they: - CORRECT
ANSWER: Decrease myocardial oxygen demand by decreasing heart rate and vascular
resistance
Beta blockers have favorable effects on survival and disease progression in heart
failure. Treatment should be initiated when the: - CORRECT ANSWER: Left ventricular
dysfunction is diagnosed
Bethanechol: - CORRECT ANSWER: Increases detrusor muscle tone to empty the
bladder
Carvedilol is heavily metabolized by CYP2D6 and 2C9, resulting in drug interactions
with which of the following drug classes? - CORRECT ANSWER: Histamine 2 blockers
Quinolones
Serotonin re-uptake
inhibitors
Charlie is a 65-year-old male who has been diagnosed with hypertension and benign
prostatic hyperplasia. Doxazosin has been chosen to treat his hypertension because it: -
CORRECT ANSWER: Relaxes smooth muscle in the bladder neck
Cholinergic blockers are used to: - CORRECT ANSWER: Counteract the extrapyramidal
symptoms (EPS) effects of phenothiazines
Control tremors and relax smooth muscle in Parkinson's disease
Inhibit the muscarinic action of ACh on bladder muscle
, Clinical dosing of Bethanechol: - CORRECT ANSWER: Starts at 5 mg to 10 mg PO and
is repeated every hour until a satisfactory clinical response is achieved
Clonidine has several off-label uses, including:
1. Alcohol and nicotine withdrawal
2.Post-herpetic neuralgia
3. Both 1 and 2
4. Neither 1 nor 2 - CORRECT ANSWER: 3. Both 1 and 2
Combined alpha-beta antagonists are used to reduce the progression of heart failure
because they: - CORRECT ANSWER: Vasodilate the peripheral vasculature
Jim is being treated for hypertension. Because he has a history of heart attack, the drug
chosen is atenolol. Beta blockers treat hypertension by: - CORRECT ANSWER:
Reducing vascular smooth muscle tone
John has clonidine, a centrally acting adrenergic blocker, prescribed for his
hypertension. He should: - CORRECT ANSWER: Not miss a dose or stop taking the
drug because of potential rebound hypertension
Nicotine gum products are: - CORRECT ANSWER: Bound to exchange resins so the
nicotine is only released during chewing
Nicotine has a variety of effects on nicotinic receptors throughout the body. Which of the
following is NOT an effect of nicotine? - CORRECT ANSWER: Vasodilation and
decreased heart rate
Nicotine replacement therapy (NRT): - CORRECT ANSWER: Delays healing of
esophagitis and peptic ulcers