NAPLEX SPECIAL POPULATIONS- TRANSPLANT PRACTICE EXAM Q&A TESTED AND APPROVED!!

Page|1




NAPLEX SPECIAL POPULATIONS-

TRANSPLANT PRACTICE EXAM Q&A TESTED
AND APPROVED!!




true or false induction immunosuppression is not required if transplant is from
an identical twin -- ANSWER--true




calcineurin inhibitor (CNI) examples -- ANSWER--cyclosporine tacrolimus



maintenance immunosuppression treatment -- ANSWER--1st line = tacrolimus
alt = beltacept



maintenance immunosuppression treatment




adjuvant medications -- ANSWER--antiproliferative agents (mycophenolate,
azathioprine)




1st line = mycophenolate alt
= mTOR inhibitor

, Page|2




maintenance immunosuppression treatment




steroids -- ANSWER--typically prednisone




if low immunological risk steroids can be discontinued




acute cellular rejection treatment -- ANSWER--high dose steroids optimize
maintenance



antibody mediated rejection treatment -- ANSWER--removing graft




plasmapheresis, IVIG, steroids + rituximab




blood group A

- can give blood to

- can receive blood from -- ANSWER--can give blood to:

-A

, Page|3




- AB




can receive blood from:

-A

-O




induction immunosuppression agents -- ANSWER--- basiliximab (IL-2 receptor
antagonist); only for prevention

- antithymocyte globulin

- alemetuzumab

- high dose IV steroids




blood group AB

- can give blood to

- can receive blood from -- ANSWER--can give blood to: AB




can receive blood from: everyone (universal receiver)

, Page|4




- AB

-A

-B

-O




blood group B

- can give blood to

- can receive blood from -- ANSWER--can give blood to:

-B

- AB




can receive blood from:

-B

-O



blood group O

- can give blood to