NU 641 Exam 3 with precise detailed solutions ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
Terms in this set (77) ||//\\|| ||//\\|| ||//\\|| ||//\\||
Original
drugs used for parkinson's ||//\\|| ||//\\|| ||//\\||
dopaminergic
anticholinergic
levodopa - how is it used and why combined with carbidopa ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
how used: as dopamine replacement in parkinsons undergoes conversion to DA in brain and
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
activates DA receptors. ||//\\|| ||//\\||
why: blocks destruction of levodopa in periphery to decrease amount of decarboxylation so
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
more drug can enter CNS and increase dopamine synthesis (ties up vitamin b 6)
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
patient education levodopa ||//\\|| ||//\\||
avoid high protein meals delays drug ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
can have on/off period - tell MD
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
N/V common take with fruits/veggies
||//\\|| ||//\\|| ||//\\|| ||//\\||
monitor cardiac s/s and renal/liver function ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
psychosis see MD ||//\\|| ||//\\||
what can't you combined levodopa with?
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
antipsychotics decrease effectiveness ||//\\|| ||//\\||
MAO increase toxicity ||//\\|| ||//\\||
pramipexole - what is it used for? ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
- parkinsons as dopamine agonist in early stages of PD to improve motor function and
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
combined with levodopa in advance stages to reduce fluctuations of motor control ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
, - restless leg syndrome
||//\\|| ||//\\|| ||//\\||
SE pramipexole
||//\\||
nausea, dizziness, somulence, insomnia, constipation, hallucinations, SLEEP ATTACKS &
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
IMPULSE CONTROL DISORDERS (screen for this) ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
has less sleep attacks than other agents
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
what drug increases pramipexole levels? ||//\\|| ||//\\|| ||//\\|| ||//\\||
cimetidine
what drug is used to treat n/v in apomorphine||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
trimethobenzamide (Tigan) 3 days before taking. Cannot combine with other antimetics risk ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
for postural hypotension and decrease effectiveness of drug.
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
what is apomorphine used for? ||//\\|| ||//\\|| ||//\\|| ||//\\||
acute hypomobility during off episodes in advance PD given by injection
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
apomorphine SE ||//\\||
Severe N/V ||//\\||
Hypotension
hyper sexuality ||//\\||
cholinesterase agents for ALZ ||//\\|| ||//\\|| ||//\\||
donzepil
galantamine
rivastigmine
which alz med is irreversible inhibition? ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
rivastigmine
how do cholinesterase agents work ||//\\|| ||//\\|| ||//\\|| ||//\\||
prevent breakdown of ACH and increase availability of ach at synapses. important for ALZ to
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
improve symptoms because nerve cells are lost during this disease. ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
cholinesterase SE ||//\\||
GI: n/v/dyspepsia/diarrhea
||//\\||
dizziness/headache
Terms in this set (77) ||//\\|| ||//\\|| ||//\\|| ||//\\||
Original
drugs used for parkinson's ||//\\|| ||//\\|| ||//\\||
dopaminergic
anticholinergic
levodopa - how is it used and why combined with carbidopa ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
how used: as dopamine replacement in parkinsons undergoes conversion to DA in brain and
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
activates DA receptors. ||//\\|| ||//\\||
why: blocks destruction of levodopa in periphery to decrease amount of decarboxylation so
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
more drug can enter CNS and increase dopamine synthesis (ties up vitamin b 6)
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
patient education levodopa ||//\\|| ||//\\||
avoid high protein meals delays drug ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
can have on/off period - tell MD
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
N/V common take with fruits/veggies
||//\\|| ||//\\|| ||//\\|| ||//\\||
monitor cardiac s/s and renal/liver function ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
psychosis see MD ||//\\|| ||//\\||
what can't you combined levodopa with?
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
antipsychotics decrease effectiveness ||//\\|| ||//\\||
MAO increase toxicity ||//\\|| ||//\\||
pramipexole - what is it used for? ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
- parkinsons as dopamine agonist in early stages of PD to improve motor function and
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
combined with levodopa in advance stages to reduce fluctuations of motor control ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
, - restless leg syndrome
||//\\|| ||//\\|| ||//\\||
SE pramipexole
||//\\||
nausea, dizziness, somulence, insomnia, constipation, hallucinations, SLEEP ATTACKS &
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
IMPULSE CONTROL DISORDERS (screen for this) ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
has less sleep attacks than other agents
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
what drug increases pramipexole levels? ||//\\|| ||//\\|| ||//\\|| ||//\\||
cimetidine
what drug is used to treat n/v in apomorphine||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
trimethobenzamide (Tigan) 3 days before taking. Cannot combine with other antimetics risk ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
for postural hypotension and decrease effectiveness of drug.
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
what is apomorphine used for? ||//\\|| ||//\\|| ||//\\|| ||//\\||
acute hypomobility during off episodes in advance PD given by injection
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
apomorphine SE ||//\\||
Severe N/V ||//\\||
Hypotension
hyper sexuality ||//\\||
cholinesterase agents for ALZ ||//\\|| ||//\\|| ||//\\||
donzepil
galantamine
rivastigmine
which alz med is irreversible inhibition? ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
rivastigmine
how do cholinesterase agents work ||//\\|| ||//\\|| ||//\\|| ||//\\||
prevent breakdown of ACH and increase availability of ach at synapses. important for ALZ to
||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
improve symptoms because nerve cells are lost during this disease. ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\|| ||//\\||
cholinesterase SE ||//\\||
GI: n/v/dyspepsia/diarrhea
||//\\||
dizziness/headache
