Cellular Biochemistry Final Exam.
The breakdown of glucose to pyruvate by a cell is an example of what type of reaction?
A)Catabolic
B)Aerobic
C)Anabolic
D)Synthetic
E)Apoptotic - (answer)Catabolic
You are a physician treating a person for a condition called galactosemia, in which the patient cannot
metabolize galactose and galactose-1-P accumulates, but has no effect on metabolism of glycogen,
starch or on glycolysis. What other dietary sugar might you recommend the patient not consume to
avoid high galactose levels associated with galactosemia?
A)fructose
B)maltose
C)lactose
D)glucose - (answer)Lactose
The constituents of the electron transport chain have similar capabilities, with the exception of
ubiquinone (coenzyme Q). What is the difference about ubiquinone?
A)Ubiquinone is a lipid soluble and so can move through the inner mitochondrial membrane.
B)Ubiquinone is a protein that is a constituent of all cells, prokaryotic or eukaryotic; hence its name
originating from "ubiquitous".
C)Ubiquinone is a protein that serves as a regulator of the rate of redox reactions in the electron
transport chain.
D)Ubiquinone is a protein that begins the electron transport chain, so it accepts the highest-energy
electrons. - (answer)Ubiquinone is a lipid soluble and so can move through the inner mitochondrial
membrane.
,Cellular Biochemistry Final Exam.
The gross output of ATP from glycolysis is ____________, whereas the net output of ATP is
____________.
A) 2; 1
B) 2; 4
C) 4; 2
D) 4; 1
E) 6; 4 - (answer)4; 2
Aldolase breaks down fructose-1,6-bisphosphate into two trioses that are:
A) each doubly phosphorylated.
B) different and each singly phosphorylated.
C) identical and each doubly phosphorylated.
D) identical.
E) different and each doubly phosphorylated. - (answer)different and each singly phosphorylated.
Which of the following can be used as a metabolic control mechanism?
A) Regulation of enzyme degradation.
B) Enzyme compartmentation
C) Action of hormones
D) Covalent modification of an enzyme
E) All of the above - (answer)All of the above
In eukaryotes, pyruvate is converted to acetyl CoA
A) in the cellular cytosol.
,Cellular Biochemistry Final Exam.
B) during passage through the inner mitochondrial membrane
C) in the mitochondrial matrix
D) during passage through the mitochondrial outer membrane.
E) in the intermembrane space. - (answer)in the mitochondrial matrix.
A temporary oxygen deficit during strenuous exercise causes a muscle to
A) synthesize glycogen.
B) synthesize muscle proteins in response to steroid hormone stimulation.
C) ferment pyruvate to lactate.
D) switch to aerobic glycolysis.
E) synthesize more NAD+. - (answer)ferment pyruvate to lactate.
When dinitrophenol is added to mitochondria, the inner membrane becomes permeable to protons.
Would you expect ATP synthesis to change?
A) There will be no change.
B) ATP will decrease.
C) ATP will increase. - (answer)ATP will decrease.
Three of the ten glycolysis enzyme reactions are not simply reversed in gluconeogenesis and require
different enzymes because
A) These three glycolytic steps are the most highly exergonic and thermodynamically difficult to reverse.
B) NAD+ needs to be generated from NADH at each of these three steps.
C) All three steps require hydrolysis of ATP for gluconeogenesis.
D) These three glycolytic enzymes are not present in the cells performing gluconeogenesis.
, Cellular Biochemistry Final Exam.
E) These three glycolytic enzymes cannot catalyze the reaction in the reverse direction under any
circumstances. - (answer)These three glycolytic steps are the most highly exergonic and
thermodynamically difficult to reverse.
Each of the following numbered respiratory complexes is correctly paired with its name except
A) complex IV: cytochrome c reductase complex
B) complex I: NADH-coenzyme Q oxidoreductase complex
C) complex II: succinate-coenzyme Q oxidoreductase complex
D) complex III: coenzyme Q-cytochrome c oxidoreductase complex
E) None of the above are correctly paired. - (answer)complex IV: cytochrome c reductase complex
In prokaryotes that carry out aerobic respiration, the _____________ serves the same purpose as the
inner mitochondrial membrane and the ___________ serves the same puprpose as the mitochondrial
matrix.
A) cytoplasm; cell wall
B) ribosomes; plasma membrane
C) cytoplasm; nucleoid
D) cytoplasm; plasma membrane
E) plasma membrane; cytoplasm - (answer)plasma membrane; cytoplasm
When electrons flow through the electron transport system from NADH to oxygen, what is the sequence
of molecules through which they move?
A) complex I, coenzyme Q, complex III, complex IV, O2
B) complex II, coenzyme Q, complex III, complex IV, O2
C) complex I, cytochrome c, complex III, coenzyme Q, complex IV, O2
D) complex I, coenzyme Q, complex IV, cytochrome c, O2
The breakdown of glucose to pyruvate by a cell is an example of what type of reaction?
A)Catabolic
B)Aerobic
C)Anabolic
D)Synthetic
E)Apoptotic - (answer)Catabolic
You are a physician treating a person for a condition called galactosemia, in which the patient cannot
metabolize galactose and galactose-1-P accumulates, but has no effect on metabolism of glycogen,
starch or on glycolysis. What other dietary sugar might you recommend the patient not consume to
avoid high galactose levels associated with galactosemia?
A)fructose
B)maltose
C)lactose
D)glucose - (answer)Lactose
The constituents of the electron transport chain have similar capabilities, with the exception of
ubiquinone (coenzyme Q). What is the difference about ubiquinone?
A)Ubiquinone is a lipid soluble and so can move through the inner mitochondrial membrane.
B)Ubiquinone is a protein that is a constituent of all cells, prokaryotic or eukaryotic; hence its name
originating from "ubiquitous".
C)Ubiquinone is a protein that serves as a regulator of the rate of redox reactions in the electron
transport chain.
D)Ubiquinone is a protein that begins the electron transport chain, so it accepts the highest-energy
electrons. - (answer)Ubiquinone is a lipid soluble and so can move through the inner mitochondrial
membrane.
,Cellular Biochemistry Final Exam.
The gross output of ATP from glycolysis is ____________, whereas the net output of ATP is
____________.
A) 2; 1
B) 2; 4
C) 4; 2
D) 4; 1
E) 6; 4 - (answer)4; 2
Aldolase breaks down fructose-1,6-bisphosphate into two trioses that are:
A) each doubly phosphorylated.
B) different and each singly phosphorylated.
C) identical and each doubly phosphorylated.
D) identical.
E) different and each doubly phosphorylated. - (answer)different and each singly phosphorylated.
Which of the following can be used as a metabolic control mechanism?
A) Regulation of enzyme degradation.
B) Enzyme compartmentation
C) Action of hormones
D) Covalent modification of an enzyme
E) All of the above - (answer)All of the above
In eukaryotes, pyruvate is converted to acetyl CoA
A) in the cellular cytosol.
,Cellular Biochemistry Final Exam.
B) during passage through the inner mitochondrial membrane
C) in the mitochondrial matrix
D) during passage through the mitochondrial outer membrane.
E) in the intermembrane space. - (answer)in the mitochondrial matrix.
A temporary oxygen deficit during strenuous exercise causes a muscle to
A) synthesize glycogen.
B) synthesize muscle proteins in response to steroid hormone stimulation.
C) ferment pyruvate to lactate.
D) switch to aerobic glycolysis.
E) synthesize more NAD+. - (answer)ferment pyruvate to lactate.
When dinitrophenol is added to mitochondria, the inner membrane becomes permeable to protons.
Would you expect ATP synthesis to change?
A) There will be no change.
B) ATP will decrease.
C) ATP will increase. - (answer)ATP will decrease.
Three of the ten glycolysis enzyme reactions are not simply reversed in gluconeogenesis and require
different enzymes because
A) These three glycolytic steps are the most highly exergonic and thermodynamically difficult to reverse.
B) NAD+ needs to be generated from NADH at each of these three steps.
C) All three steps require hydrolysis of ATP for gluconeogenesis.
D) These three glycolytic enzymes are not present in the cells performing gluconeogenesis.
, Cellular Biochemistry Final Exam.
E) These three glycolytic enzymes cannot catalyze the reaction in the reverse direction under any
circumstances. - (answer)These three glycolytic steps are the most highly exergonic and
thermodynamically difficult to reverse.
Each of the following numbered respiratory complexes is correctly paired with its name except
A) complex IV: cytochrome c reductase complex
B) complex I: NADH-coenzyme Q oxidoreductase complex
C) complex II: succinate-coenzyme Q oxidoreductase complex
D) complex III: coenzyme Q-cytochrome c oxidoreductase complex
E) None of the above are correctly paired. - (answer)complex IV: cytochrome c reductase complex
In prokaryotes that carry out aerobic respiration, the _____________ serves the same purpose as the
inner mitochondrial membrane and the ___________ serves the same puprpose as the mitochondrial
matrix.
A) cytoplasm; cell wall
B) ribosomes; plasma membrane
C) cytoplasm; nucleoid
D) cytoplasm; plasma membrane
E) plasma membrane; cytoplasm - (answer)plasma membrane; cytoplasm
When electrons flow through the electron transport system from NADH to oxygen, what is the sequence
of molecules through which they move?
A) complex I, coenzyme Q, complex III, complex IV, O2
B) complex II, coenzyme Q, complex III, complex IV, O2
C) complex I, cytochrome c, complex III, coenzyme Q, complex IV, O2
D) complex I, coenzyme Q, complex IV, cytochrome c, O2
