Test Bank for Clinical Calculations 10th Edition by Kee

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Chapter 07: Methods of Calculation for Individualized Drug Dosing
A A A A A A A A

Kee: Clinical Calculations: With Applications to General and Specialty Areas, 10th
A A A A A A A A A A

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BodyASurfaceAAreaAbyASquareARoot

1. Order:AcyclophosphamideA500Amg/m2AinA500AmLAofAnormalAsalineAsolutionA(NSS)AoverA9
0Aminutes
PatientAheightAandAweight:A5AftA10Ain,A142Alb
DrugAavailable:AcyclophosphamideA100AmgAdiluteAwithA5AmLAofAsterileAwater;AyieldsA20Amg/m
L
a. WhatAisAtheApatient’sAbodyAsurfaceAareaA(BSA)A(m2)?
b. WhatAisAtheAtotalAdose?
c. HowAmanyAmillilitersAshouldAyouAprepare?

ANS:

a.
b. 500Amg/m2AA1.78Am2A=A890Amg
c. FE:A890Amg/100AmgAA5AmLA=A44.5AmL

OR




2. Order:AcisplatinA50Amg/m2AinA500AmLAofANSSAintravenouslyAoverA90Aminut
esAPatientAheightAandAweight:A5AftA6Ain,A160Alb
DrugAavailable:AcisplatinA100Amg/100AmL
a. WhatAisAtheApatient’sABSAA(m2)?
b. WhatAisAtheAtotalAdose?
c. HowAmanyAmillilitersAshouldAyouAprepare?

ANS:

a.
b. 50AmgAA1.84Am2A=A92Amg
c. FE:A92Amg/100AmgAA100AmLA=A92AmL

OR




3. ForAtheAfollowingAquestions,AuseAtheAsquareArootAmethodAand/orAnomogram.ANoteAdiscrepanci
esAbetweenAmethods.



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GiveAdacarbazineA250Amg/m2/dayAA5Adays.A
PatientAheight:A5AftA10Ain
PatientAweight:A173AlbAWh
atAisAtheAdailyAdoseAwith
a. squareArootAmethod?
b. nomogram?

ANS:

a.
250Amg/m2/dayAA1.97Am2A=A493Amg/day
b. HeightA70Ain,AweightA173Alb,AintersectsA2.02Am
A250Amg/m /dayAA2.02Am A=A505AA500Amg/da
2 2 2

y

4. ForAtheAfollowingAquestions,AuseAtheAsquareArootAmethodAand/orAnomogram.ANoteAdiscrepanci
esAbetweenAmethods.




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GiveA5-
fluorouracilA450Amg/m2/wk.APatientA
height:A5AftA6Ain
PatientAweight:A210Alb
WhatAisAtheAweeklyAdoseAwith
a. squareArootAmethod?
b. nomogram?

ANS:

a.
450Amg/m2/wkAA2.10Am2A=A945Amg/wk
b. HeightA66Ain,AweightA210Alb,AintersectsA2.04Am
A450Amg/m /wkAA2.04Am A=A918AA920Amg/wk
2 2 2


5. ForAtheAfollowingAquestions,AuseAtheAsquareArootAmethodAand/orAnomogram.ANoteAdiscrepanci
esAbetweenAmethods.




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