1.What are the fundamental concepts of Physiology?
ANS Homeostasis Feedback
Redundancy
Integration
2.Define Homeostasis ANS Maintaining physiological variables within a relatively
narrow range, regardless of the external (outside temp.) stress or internal stress (low
blood sugar).
3.Two kinds of Feedback ANS Positive Feedback (1-5%)
Negative Feedback (95-99%)
4.The idea of Negative Feedback
ANS When a sensor (thermostat) detects a level (set point) of the output (cold air) of a
controller (A/C unit) and leads to LESS OUTPUT.
5.Example of Negative Feedback Scenario ANS Insulin secretion in response to high
blood glucose, when blood glucose levels drop, insulin secretion stops.
, ADVANCED PHYSIOLOGY EXAM 1 STUDY GUIDE
6.Positive Feedback ANS LEADS TO MORE OUTPUT
7.Example of Positive feedback scenario ANS Oxytocin released in response to
contractions of uterus and leads to MORE contractions of uterus
8.Define Redundancy ANS having more than one system in place to HELP attain the goal
of homeostasis.
9. Example of Redundancy: ANS Insulin/Glucagon primary mechanism Growth
Hormone- also INFLUENCES blood glucose.
10. Define Integration: ANS The working together of multiple physiological systems to
maintain homeostasis.
11. Example of Integration ANS GOAL: maintain adequate perfusion of oxygenated
blood to ALL tissue. Cardiovascular system MUST work with respiratory system.
, ADVANCED PHYSIOLOGY EXAM 1 STUDY GUIDE
12. ACH ACHE ACHE Inhibitor ANS ACH- acetylcholine
ACHE - Pacman -eats acetylcholine
ACHE Inhibitor - bug spray (kills
pacman)
13. Serotonin: Similar example to
ACH.
too little 5HT = depression
Serotonin Reuptake
SSRI's - Selective Serotonin Reuptake Inhibitors
14. Antagonist ANS binds, but no effect
15. Agonist ANS mimic effect of hormone or neurotransmitter