correct answers
alpha 1 receptors are found in ----causing----- - correct answer ✔✔ smooth muscle
/vasoconstriction
While alpha 1 receptors cause vasoconstriction it can also cause ------ where? - correct answer
✔✔ relaxation/GI smooth muscle
Beta 1 receptors are found - correct answer ✔✔ The heart
When beta 1 receptors are stimulated, 3 things happen.... - correct answer ✔✔ 1). Increase in
force of contraction
2. increase in heart rate
3). increase in conduction
Beta 3 receptors decreases - correct answer ✔✔ urinary frequency of bladder contractions
which increases filling phase of bladder
Beta 2 receptors - correct answer ✔✔ bronchodilation in lungs
Some beta 2 receptor drugs - correct answer ✔✔ -terol drugs like albuterol, ephedrine,
terbutaline
Nasal Decongestants - correct answer ✔✔ alpha 1 receptors
,Nasal Decongestant drugs - correct answer ✔✔ ephedrine, tetrahydrozoline, naphazoline
Ophthalmics stimulate ---- causing----- - correct answer ✔✔ alpha receptors /arteriole
vasoncontriction
Adrenergics in eyes can treat - correct answer ✔✔ open angle glaucoma
adrenergics in the eyes can reduce - correct answer ✔✔ intraocular pressur e
Adrenergics in the eyes can dilate the eyes by stimulating ---- and ---- receptors - correct answer
✔✔ alpha/beta 2
adverse for alpha receptor drugs - correct answer ✔✔ headache, insomnia, euphoria,
hypertension, reflexive bradycardia
adverse for beta receptor drugs - correct answer ✔✔ headache, dizziness, dysrhythmias and
fluctuations in BP
toxic effects of adrenergic drugs (2 most life threatening) and ---- - correct answer ✔✔
CNS/Cardiovascular systems /seizures
adrenergic drugs have very short ---- - correct answer ✔✔ half lives
Since adrenergic drugs have short half lives, if overdosed what can be done to fix the situation?
- correct answer ✔✔ Stopping the drug
Dobutamine - correct answer ✔✔ beta 1 agonist
-inotropic agent, inc. contractility and CO, does NOT inc HR.
,-used in acute management of heart failure
Dopamine - correct answer ✔✔ beta 1 and alpha 1
dopamine at low doses - correct answer ✔✔ dilate blood vessels in the brain and kidneys
dopamine at higher doses - correct answer ✔✔ heart contractility and CO
dopamine at highest doses - correct answer ✔✔ alpha 1 / vasoconstriction
dopamine is contraindicated in patients who have - correct answer ✔✔ pheochromocytoma
Epinephrine acts on both the ---- and ----- - correct answer ✔✔ alpha and beta receptors
epinephrine is a ------ adrenergic agonist - correct answer ✔✔ nonselective
epinephrine at low doses stimulates -----receptors and increases ---- of -----and ----- - correct
answer ✔✔ beta 1/force of contraction/heart rate
epinephrine is also a ------treating anaphylactic shock - correct answer ✔✔ bronchodilator
epinephrine has broncodilatory effects on the ---- receptors - correct answer ✔✔ beta 2
epinephrine at high doses acts as a -----elevating-----and acts on ----- receptors - correct answer
✔✔ vasoconstrictor/blood pressure /alpha
, Fenoldapam is a peripheral ---- agonist lowering---- - correct answer ✔✔ dopamine 1 (D1)
/blood pressure
Fenoldopam also increases ------ - correct answer ✔✔ renal flow
Midodrine acts on ---- receptors - correct answer ✔✔ alpha 1
Midodrine treats ----- - correct answer ✔✔ orthostatic hypotension
Midodrine is a peripheral ------ - correct answer ✔✔ vasoconstrictor
Mirabegron is a ----- agonist - correct answer ✔✔ Beta 3
Mirabegron - correct answer ✔✔ Urinary Bladder Modifier
Norepinephrine leads to and acts on ----- receptors - correct answer ✔✔ vasonconstriction
/alpha
Norepinephrine effects both ---- and ---- receptors but does not effect the ----- - correct answer
✔✔ alpha/beta 1 /lungs
Norepinephrine is metabolized to - correct answer ✔✔ dopamine
Norepinephrine treats ---- and ----- - correct answer ✔✔ hypotension and shock
new drug ---- is converted to norepinphrine - correct answer ✔✔ Droxidopa