Pharmacotherapeutics for Advanced Practice Nurse Prescribers Exam 1,2&3
COMBINATION examination 2025 -2026 QUESTIONS WITH CORRECT
ANSWERS VERIFIED 100% GRADED A+
Pharmacotherapeutics for Advanced Practice Nursing
Pharmacotherapeutics for Advanced Practice Nurse Prescribers
EXAM 1
Monitoring for a pregnant woman who has had a urinary tract infection is:
1. Symptom resolution in 48 hours
2. Follow-up urine culture at completion of therapy
3. "Test of cure" urinary analysis at completion of therapy
4. Follow-up urine culture every 2 weeks until delivery
4
Along with an antibiotic prescription, lifestyle education for a nonpregnant
adult female who has had a urinary tract infection includes:
1. Increasing her intake of vitamin C-containing orange juice
2. Voiding 10 to 15 minutes after intercourse
3. Avoiding ingesting urinary irritants, such as asparagus
4. All of the above
2
Lisa is a healthy nonpregnant adult woman who recently had a urinary tract
infection (UTI). She is asking about drinking cranberry juice to prevent a
recurrence of the UTI. The correct answer to give her would be:
1. Sixteen ounces per day of cranberry juice cocktail will prevent UTIs.
2. 100% cranberry juice or cranberry juice extract may decrease UTIs in some
patients.
3. There is no evidence that cranberry juice helps prevent UTIs.
4. Cranberry juice only works to prevent UTIs in children.
,2
When Sam used clotrimazole (Lotrimin AF) for athlete's foot he developed a
red, itchy rash consistent with a hypersensitivity reaction. He now has
athlete's foot again. What would be a good choice of antifungal for Sam?
1. Miconazole (Micatin) powder
2. Ketoconazole (Nizoral) cream
3. Terbinafine (Lamisil) cream
4. Griseofulvin (Grifulvin V) suspension
3
When prescribing topical penciclovir (Denavir) for the treatment of herpes
labialis (cold sores) patient education would include:
1. Spread penciclovir liberally all over lips and area surrounding lips.
2. Penciclovir therapy is started at the first sign of a cold sore outbreak.
3. Skin irritation is normal with penciclovir and it should resolve.
4. The penciclovir should be used a minimum of 2 weeks to prevent
recurrence.
2
Topical diphenhydramine (Benadryl) is available OTC to treat itching. Patients
or parents should be instructed regarding the use of topical diphenhydramine
that:
1. For maximum effectiveness in treating itching, combine topical with oral
diphenhydramine.
2. Topical diphenhydramine is the treatment of choice in treating poison ivy or
poison oak.
3. Topical diphenhydramine should not be used in children younger than age 2
years.
4. When applying topical diphenhydramine, apply the cream liberally to all
areas that itch.
3
Absolute contraindications to estrogen therapy include:
1. History of any type of cancer
2. Clotting disorders
3. History of tension headaches
4. Orthostatic hypotension
,2
Women who have migraines with an aura should not be prescribed estrogen
because of:
1. The interaction between triptans and estrogen, limiting migraine therapy
choices
2. An increased incidence of migraines with the use of estrogen
3. An increased risk of stroke occurring with estrogen use
4. Patients with migraines may be prescribed estrogen without any concerns
3
A 19-year-old female is a nasal Staph aureus carrier and is placed on 5 days of
rifampin for treatment. Her only other medication is combined oral
contraceptives. What education should she receive regarding her
medications?
1. Separate the oral ingestion of the rifampin and oral contraceptive by at least
an hour.
2. Both medications are best tolerated if taken on an empty stomach.
3. She should use a back-up method of birth control such as condoms for the
rest of the current pill pack.
4. If she gets nauseated with the medications she should call the office for an
antiemetic prescription.
3
A 56-year-old woman is complaining of vaginal dryness and dyspareunia. To
treat her symptoms with the lowest adverse effects she should be prescribed:
1. Low-dose oral estrogen
2. A low-dose estrogen/progesterone combination
3. A vaginal estradiol ring
4. Vaginal progesterone cream
3
The goals of treatment when prescribing for sexually transmitted infections
include:
1. Treatment of infection
2. Prevention of disease spread
3. Prevention of long-term sequelae from the infection
4. All of the above
, 4
The drug of choice for treatment of primary or secondary syphilis is:
1. Ceftriaxone IM
2. Benzathine penicillin G IM
3. Oral azithromycin
4. Oral ciprofloxacin
2
The drug of choice for treatment of early latent or tertiary syphilis is:
1. Ceftriaxone IM
2. Benzathine penicillin G IM
3. Oral azithromycin
4. Oral ciprofloxacin
2
Patricia has been prescribed doxycycline for a chlamydia infection. She is
healthy and her only medication is an oral combined contraceptive. Patricia's
education would include:
1. Use a back-up method of birth control (condom) until her next menses.
2. Doxycycline may cause tendonitis and she should report any joint pain.
3. Her partner will need treatment if her infection doesn't clear with the
doxycycline.
4. Doxycycline is used for one-dose treatment of STIs; take the whole
prescription at once.
1
When prescribing metronidazole (Flagyl) to treat bacterial vaginosis, patient
education would include:
1. Metronidazole is safe in the first trimester of pregnancy.
2. Consuming alcohol in any form may cause a severe reaction.
3. Sexual partners need concurrent therapy.
4. Headaches are a sign of a serious adverse reaction and need immediate
evaluation.
2
The treatment goals when treating urinary tract infection (UTI) include:
1. Eradication of infecting organism
COMBINATION examination 2025 -2026 QUESTIONS WITH CORRECT
ANSWERS VERIFIED 100% GRADED A+
Pharmacotherapeutics for Advanced Practice Nursing
Pharmacotherapeutics for Advanced Practice Nurse Prescribers
EXAM 1
Monitoring for a pregnant woman who has had a urinary tract infection is:
1. Symptom resolution in 48 hours
2. Follow-up urine culture at completion of therapy
3. "Test of cure" urinary analysis at completion of therapy
4. Follow-up urine culture every 2 weeks until delivery
4
Along with an antibiotic prescription, lifestyle education for a nonpregnant
adult female who has had a urinary tract infection includes:
1. Increasing her intake of vitamin C-containing orange juice
2. Voiding 10 to 15 minutes after intercourse
3. Avoiding ingesting urinary irritants, such as asparagus
4. All of the above
2
Lisa is a healthy nonpregnant adult woman who recently had a urinary tract
infection (UTI). She is asking about drinking cranberry juice to prevent a
recurrence of the UTI. The correct answer to give her would be:
1. Sixteen ounces per day of cranberry juice cocktail will prevent UTIs.
2. 100% cranberry juice or cranberry juice extract may decrease UTIs in some
patients.
3. There is no evidence that cranberry juice helps prevent UTIs.
4. Cranberry juice only works to prevent UTIs in children.
,2
When Sam used clotrimazole (Lotrimin AF) for athlete's foot he developed a
red, itchy rash consistent with a hypersensitivity reaction. He now has
athlete's foot again. What would be a good choice of antifungal for Sam?
1. Miconazole (Micatin) powder
2. Ketoconazole (Nizoral) cream
3. Terbinafine (Lamisil) cream
4. Griseofulvin (Grifulvin V) suspension
3
When prescribing topical penciclovir (Denavir) for the treatment of herpes
labialis (cold sores) patient education would include:
1. Spread penciclovir liberally all over lips and area surrounding lips.
2. Penciclovir therapy is started at the first sign of a cold sore outbreak.
3. Skin irritation is normal with penciclovir and it should resolve.
4. The penciclovir should be used a minimum of 2 weeks to prevent
recurrence.
2
Topical diphenhydramine (Benadryl) is available OTC to treat itching. Patients
or parents should be instructed regarding the use of topical diphenhydramine
that:
1. For maximum effectiveness in treating itching, combine topical with oral
diphenhydramine.
2. Topical diphenhydramine is the treatment of choice in treating poison ivy or
poison oak.
3. Topical diphenhydramine should not be used in children younger than age 2
years.
4. When applying topical diphenhydramine, apply the cream liberally to all
areas that itch.
3
Absolute contraindications to estrogen therapy include:
1. History of any type of cancer
2. Clotting disorders
3. History of tension headaches
4. Orthostatic hypotension
,2
Women who have migraines with an aura should not be prescribed estrogen
because of:
1. The interaction between triptans and estrogen, limiting migraine therapy
choices
2. An increased incidence of migraines with the use of estrogen
3. An increased risk of stroke occurring with estrogen use
4. Patients with migraines may be prescribed estrogen without any concerns
3
A 19-year-old female is a nasal Staph aureus carrier and is placed on 5 days of
rifampin for treatment. Her only other medication is combined oral
contraceptives. What education should she receive regarding her
medications?
1. Separate the oral ingestion of the rifampin and oral contraceptive by at least
an hour.
2. Both medications are best tolerated if taken on an empty stomach.
3. She should use a back-up method of birth control such as condoms for the
rest of the current pill pack.
4. If she gets nauseated with the medications she should call the office for an
antiemetic prescription.
3
A 56-year-old woman is complaining of vaginal dryness and dyspareunia. To
treat her symptoms with the lowest adverse effects she should be prescribed:
1. Low-dose oral estrogen
2. A low-dose estrogen/progesterone combination
3. A vaginal estradiol ring
4. Vaginal progesterone cream
3
The goals of treatment when prescribing for sexually transmitted infections
include:
1. Treatment of infection
2. Prevention of disease spread
3. Prevention of long-term sequelae from the infection
4. All of the above
, 4
The drug of choice for treatment of primary or secondary syphilis is:
1. Ceftriaxone IM
2. Benzathine penicillin G IM
3. Oral azithromycin
4. Oral ciprofloxacin
2
The drug of choice for treatment of early latent or tertiary syphilis is:
1. Ceftriaxone IM
2. Benzathine penicillin G IM
3. Oral azithromycin
4. Oral ciprofloxacin
2
Patricia has been prescribed doxycycline for a chlamydia infection. She is
healthy and her only medication is an oral combined contraceptive. Patricia's
education would include:
1. Use a back-up method of birth control (condom) until her next menses.
2. Doxycycline may cause tendonitis and she should report any joint pain.
3. Her partner will need treatment if her infection doesn't clear with the
doxycycline.
4. Doxycycline is used for one-dose treatment of STIs; take the whole
prescription at once.
1
When prescribing metronidazole (Flagyl) to treat bacterial vaginosis, patient
education would include:
1. Metronidazole is safe in the first trimester of pregnancy.
2. Consuming alcohol in any form may cause a severe reaction.
3. Sexual partners need concurrent therapy.
4. Headaches are a sign of a serious adverse reaction and need immediate
evaluation.
2
The treatment goals when treating urinary tract infection (UTI) include:
1. Eradication of infecting organism
